Teachers are expected to tailor their instruction to accommodate differences between students, in order to give all learners the opportunity to develop to their full potential. This is also called differentiated instruction (DI), and it requires teachers to continually monitor students’ progress towards the lesson goal and adjust their instruction accordingly. This is a complex skill for many teachers that they do not always implement. The goal of this dissertation was to research how educators can be supported in providing differentiation. In Study 1 we observed secondary school teachers with strong DI skills in their classrooms and interviewed them afterwards to analyse their decision-making processes. The findings of this study informed the design and implementation of a professional development program in Study 2, which was based on a whole-task approach where the participant teachers work on authentic tasks that require the integration of skills and knowledge, increasing the likelihood of transfer to practice. The impact of this professional development program on teachers’ DI practices was examined in Study 3, both from the teacher and student perspective. Results from both perspectives showed that all teachers made more intentional adaptations. To explore whether the findings of the first three studies were transferable to another context, we shifted the focus to students with hearing and/or communicative impairments (HCI). Instead of a single teacher, often a team of professionals has joint responsibility for HCI students’ education. In Study 4, we researched what providing DI and interprofessional collaboration in the HCI context looks like, by conducting a systematic literature review and an exploration of practice through focus group sessions. We found that there are four phases (preparing a lesson series, preparing a lesson, enacting a lesson, and evaluating the lesson) and five principles (work in a goal-oriented way, monitor continually, challenge all students, adapt the instruction, and stimulate self-regulation) that could be identified in DI across various educational contexts. The four phases and five principles can be used as a framework to support educators in improving their DI skills and thus making good, informed decisions that allow all their students to realise their learning potential.
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Protein acylation via metabolic acyl-CoA intermediates provides a link between cellular metabolism and protein functionality. A process in which acetyl-CoA and acetylation are fine-tuned is during myogenic differentiation. However, the roles of other protein acylations remain unknown. Protein propionylation could be functionally relevant because propionyl-CoA can be derived from the catabolism of amino acids and fatty acids and was shown to decrease during muscle differentiation. We aimed to explore the potential role of protein propionylation in muscle differentiation, by mimicking a pathophysiological situation with high extracellular propionate which increases propionyl-CoA and protein propionylation, rendering it a model to study increased protein propionylation. Exposure to extracellular propionate, but not acetate, impaired myogenic differentiation in C2C12 cells and propionate exposure impaired myogenic differentiation in primary human muscle cells. Impaired differentiation was accompanied by an increase in histone propionylation as well as histone acetylation. Furthermore, chromatin immunoprecipitation showed increased histone propionylation at specific regulatory myogenic differentiation sites of the Myod gene. Intramuscular propionylcarnitine levels are higher in old compared to young males and females, possibly indicating increased propionyl-CoA levels with age. The findings suggest a role for propionylation and propionyl-CoA in regulation of muscle cell differentiation and ageing, possibly via alterations in histone acylation.
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This article argues for an updated theoretical framework in fashion studies. It proposes that perspectives emphasizing the social role and the technological nature of dress should be considered complementary, and that their joint application can contribute to new understandings of fashion history. Employing ethnographic methods, this stance is explored through a comparative analysis of the sartorial practices of two groups of women living or working in Amsterdam during the 1950s and the 2010s. A theoretical framework integrating theories of identity (mainly based on the writings of Georg Simmel and Gabriel Tarde) and the philosophy of technology (in this case the device paradigm of Albert Borgmann) allows us to uncover a paradoxical history of fashion in which clothing shifts roles, transforming from “things of imitation” into “devices of differentiation.”
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Existing observation instruments to measure differentiated instruction often lack insight into the degree to which teachers’ decisions match the actual needs of their students, and neglect the importance of preparation and evaluation. This article describes the psychometric evaluation of a comprehensive instrument (Assessing Differentiation in All Phases of Teaching; ADAPT) that does not suffer from these shortcomings. To assess its quality, 41 raters used it to score videos of lessons and interviews of 86 primary school teachers. A 5-dimensional item-response model showed good fit and high internal consistency, and a decision study was conducted to determine the reliability and agreement coefficients for different numbers of raters. For the intended low-stakes use, a single rater would be enough to provide a reliable estimate of a teacher’s overall score. Finally, rater experiences showed that ADAPT has high practical value due to the comprehensive manual and detailed score descriptions and examples. The instrument can therefore not only be used for research purposes, but can also serve as a valuable resource for teachers and teacher educators in practice.
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Vaak zien we dat (sport-) bedrijven hun productaanbod differentiëren: ze bieden verschillende varianten van een product aan die voor verschillende groepen afnemers aantrekkelijk kunnen zijn. Dit noemen we productdifferentiatie. Dit kan gerealiseerd worden door het aanbieden van productvormen van eenzelfde kwaliteit of door productvormen met een verschillend kwaliteitsniveau. Wanneer organisaties in de sportbusiness producten (en diensten) in de markt zetten die zich onderscheiden van concurrenten doordat ethische aspecten een relatief grote rol spelen in het product, de dienst, het personeel of het imago, spreken we van ethische productdiffentiatie in de sport. Veelal zien we dat het om producten gaat met een relatief hoge kwaliteit. Ethische productdifferentiatie is een marketingstrategie die zeer geschikt is voor sportbedrijven die zich bewegen in markten met veel concurrentie. Case: O'Neill.
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Background: The aim of this study is to validate a newly developed nurses' self-efficacy sources inventory. We test the validity of a five-dimensional model of sources of self-efficacy, which we contrast with the traditional four-dimensional model based on Bandura's theoretical concepts. Methods: Confirmatory factor analysis was used in the development of the newly developed self-efficacy measure. Model fit was evaluated based upon commonly recommended goodness-of-fit indices, including the χ2 of the model fit, the Root Mean Square Error of approximation (RMSEA), the Tucker-Lewis Index (TLI), the Standardized Root Mean Square Residual (SRMR), and the Bayesian Information Criterion (BIC). Results: All 22 items of the newly developed five-factor sources of self-efficacy have high factor loadings (range .40-.80). Structural equation modeling showed that a five-factor model is favoured over the four-factor model. Conclusions and implications: Results of this study show that differentiation of the vicarious experience source into a peer- and expert based source reflects better how nursing students develop self-efficacy beliefs. This has implications for clinical learning environments: a better and differentiated use of self-efficacy sources can stimulate the professional development of nursing students.
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Five methods were compared to determine the best technique for accurate identification of coagulase-negative staphylococci (CoNS) (n=142 strains). MALDI-TOF MS showed the best results for rapid and accurate CoNS differentiation (correct identity in 99.3%). An alternative to this approach could be Vitek2 combined with partial tuf gene sequencing.
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In this article, the outcomes of a survey aimed to investigate how aware of and how capable coaches in higher vocational Dutch education perceive themselves to assist students displaying mental health and well-being issues are presented. Additionally, the article explores coaches’ perceptions regarding the frequency, form of help offered, topics to be tackled and the preferred form in which this help should be provided. The author conducted a survey that gathered qualitative and quantitative data from coaches (N 5 82) at a Dutch University of Applied Sciences in the north of the Netherlands. A differentiation in coaches’ number of years of teaching and coaching experience was considered.
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Whitepaper: The use of AI is on the rise in the financial sector. Utilizing machine learning algorithms to make decisions and predictions based on the available data can be highly valuable. AI offers benefits to both financial service providers and its customers by improving service and reducing costs. Examples of AI use cases in the financial sector are: identity verification in client onboarding, transaction data analysis, fraud detection in claims management, anti-money laundering monitoring, price differentiation in car insurance, automated analysis of legal documents, and the processing of loan applications.
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The semantic differential is a widely applied measurement technique in the information systems field. As wedemonstrate in this study, however, there is evidence that many of the applications of the semantic differentialseem to be subject to common shortcomings. In this study, we address these shortcomings by creatingawareness of the requirements underlying semantic differentiation. We discuss the requirements of semanticdifferentiation and use them as a foundation to introduce a framework to assist researchers in applying thesemantic differential more adequately. The framework puts renewed emphasis on bipolar scale selection anddimensionality testing, introduces semantic bipolarity as new criterion, and proposes distinct stages for thetesting of wording and contextual contamination. We exemplify the framework using an illustration exercise,which centers on the assessment of the meaning of the concept “electronic marketplace quality”. Using amixture of qualitative and quantitative methods, the illustration exercise clarifies the prerequisites for semantic differentiation and provides suggestions for researchers. The paper concludes with a discussion of several methodological implications.
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