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3Calibration of spectral imaging instruments is a prerequisite for many applications, in particular in the field of Earth observation. In this contribution we will present a novel traceability route to celebrate spectral imaging instruments, based on tunable radiance source that is referenced to a primary detector standard.
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We have developed an SI-traceable narrow-band tunable radiance source based on an optical parametric oscillator (OPO) and an integrating sphere for the calibration of spectroradiometers. The source is calibrated with a reference detector over the ultraviolet/visible spectral range with an uncertainty of <1%. As a case study, a CubeSat spectroradiometer has been calibrated for radiance over its operating range from 370 nm to 480 nm. To validate the results, the instrument has also been calibrated with a traditional setup based on a diffuser and an FEL lamp. Both routes show good agreement within the combined measurement uncertainty. The OPO-based approach could be an interesting alternative to the traditional method, not only because of reduced measurement uncertainty, but also because it directly allows for wavelength calibration and characterization of the instrumental spectral response function and stray light effects, which could reduce calibration time and cost.
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Knowledge of the time of deposition is pivotal in forensic investigations. Recent studies show that changes in intrinsic fluorescence over time can be used to estimate the age of body fluids. These changes have been attributed to oxidative modifications caused by protein–lipid interactions. This pilot study aims to explore the impact of these modifications on body fluid fluorescence, enhancing the protein–lipid model system for age estimation. Lipid and protein oxidation markers, including protein carbonyls, dityrosine, advanced glycation end-products (AGEs), malondialdehyde (MDA), and 4-hydroxynonenal (HNE), were studied in aging semen, urine, and saliva over 21 days. Surface plasmon resonance imaging (SPRi), enzyme-linked immunosorbent assay (ELISA), and fluorescence spectroscopy were applied. Successful detection of AGE, dityrosine, MDA, and HNE occurred in semen and saliva via SPRi, while only dityrosine was detected in urine. Protein carbonyls were measured in all body fluids, but only in saliva was a significant increase observed over time. Additionally, protein fluorescence loss and fluorescent oxidation product formation were assessed, showing significant decreases in semen and saliva, but not in urine. Although optimization is needed for accurate quantification, this study reveals detectable markers for protein and lipid oxidation in aging body fluids, warranting further investigation.
MULTIFILE
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Electromagnetic articulography (EMA) is one of the instrumental phonetic research methods used for recording and assessing articulatory movements. Usually, articulographic data are analysed together with standard audio recordings. This paper, however, demonstrates how coupling the articulograph with devices providing other types of information may be used in more advanced speech research. A novel measurement system is presented that consists of the AG 500 electromagnetic articulograph, a 16-channel microphone array with a dedicated audio recorder and a video module consisting of 3 high-speed cameras. It is argued that synchronization of all these devices allows for comparative analyses of results obtained with the three components. To complement the description of the system, the article presents innovative data analysis techniques developed by the authors as well as preliminary results of the system’s accuracy.
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During image acquisition, certain topographers require the addition of sodium fluorescein (NaFl) dye to the tear film. This study investigates the effect of NaFl dye on corneal topography and tear surface quality.
MULTIFILE
Virtual Reality (VR) can bridge the gap between theoretical educative materials and complex real-life situations that ambulance nurses face in practice. The ability to simulate scenarios from a compelling caregiver perspective offers a powerful learning method. We aim to contribute to the training of ambulance nurses by utilizing new opportunities that VR offers. In this study we investigate which factors contribute to the implementation and long-term use of VR training by ambulance services for their employees. Part of project: VRAMBO. Virtual Reality voor AMBulanceverpleegkundig Onderwijs van complexe situaties
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Mirror therapy is a common therapy to help patients recover after an accident in which an arm or hand is paralyzed. It activates mirror neurons and fools the brain into perceiving the paralyzed arm or hand is still moving. This stimulates the brain which is an important aspect to improve recovery. A similar setup can now be achieved using virtual reality technologies which not only allows for the addition of gamification elements but also gives patients the opportunity to practice whenever and wherever they want. Within the project ‘Virtual Reality for Rehabilitation’ we build these virtual reality environments and study how they can improve rehabilitation therapy and complement, or change, existing rehabilitation therapy. First, we studied to what extent the effects of mirror therapy are transferable to a virtual reality environment. We are now moving into the next phase of the project to study the use of virtual reality at home. In this research we focus on the question ‘what kind of new issues and challenges are introduced when virtual reality mirror therapy is transferred to a home setting’.
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Walking is something that most of us do every day. From the moment we set our first steps we perfect this skill until it eventually becomes an automatic walking pattern. However, due to injury, illness, or disease, someone might lose control over this automated task. When this happens, physical therapy is often used to help restore a patient’s use of muscles and train a new automatic walking pattern. An important element is to reduce postural sway and increase functional reach. In some cases, this includes using a Body Weight Support system which allows patients to experience walking at an early stage of their rehabilitation. However, this also confines them to a predefined area, away from everyday situations. As continuing their rehabilitation throughout everyday life can be challenging, being able to bring these everyday situations into the rehabilitation therapy might therefore aid their transition. By transferring all of this into a virtual reality environment, it allows a therapist to do exactly that. Moreover, it allows for usage data to be collected, analyzed, and presented to provide meaningful insights. In the project ‘Virtual Reality for Rehabilitation’ we focus on the question how new technologies can facilitate natural interaction in a virtual reality environment and support, optimize and maybe even replace existing rehabilitation processes. For this we are developing a system that support both patients and therapist. A Conference object of Supporting Health by Technology 2021 at Enschede, The Netherlands.
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Infectious diseases are a severe threat to human health. We believe that smartphones may be used as a valuable non-pharmaceutical tool to fight epidemics. We designed and evaluated the capability to fight epidemics with smartphones. This is the abstract of one of the oral presentations of the International Conference Supporting Health by Technology 2021. Project : Fighting epidemics
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