Due to considerable occupational challenges and stressors, classical musicians might face increased risk for mental health issues, compared to the general population. As such, scholars have highlighted the importance of developing psychological resilience in musicians. Nevertheless, this important psychological characteristic has remained understudied within music psychology. The present study therefore examined the relationship between mental health issues and resilience. Using a cross-sectional survey design, a total of 64 musicians (including both music students and professionals) participated in this study. Results highlight that symptoms of depression/anxiety were relatively high within the current population. Moreover, music students experienced significantly more symptoms compared to professional musicians. Both resilience and general physical health were found to be negatively associated with mental health issues. The results highlight the need for further research into mental health issues in music students and provide preliminary evidence for the importance of psychological resilience in classical musicians.