The Northern Netherlands is an unique environment for sustainably-minded (bio)chemical businesses due to the regional availability of renewable feedstock, energy and existing infrastructure as well as the proximity to excellent knowledge centers and upscaling facilities. Within the last decades, several developments unravelled in the biobased circular transition. Exploring how these developments were initiated, the article means to show the opportunities that this region has to offer today. It also makes a strong argument for the economic potential arising from the creative combination of available feedstocks in an innovative ecosystem providing necessary frame-work conditions and fostering close intersectoral collaboration.