BACKGROUND: Since the placenta also has a sex, fetal sex-specific differences in the occurrence of placenta-mediated complications could exist.OBJECTIVE: To determine the association of fetal sex with multiple maternal pregnancy complications.SEARCH STRATEGY: Six electronic databases Ovid MEDLINE, EMBASE, Cochrane Central, Web-of-Science, PubMed, and Google Scholar were systematically searched to identify eligible studies. Reference lists of the included studies and contact with experts were also used for identification of studies.SELECTION CRITERIA: Observational studies that assessed fetal sex and the presence of maternal pregnancy complications within singleton pregnancies.DATA COLLECTION AND ANALYSES: Data were extracted by 2 independent reviewers using a predesigned data collection form.MAIN RESULTS: From 6522 original references, 74 studies were selected, including over 12,5 million women. Male fetal sex was associated with term pre-eclampsia (pooled OR 1.07 [95%CI 1.06 to 1.09]) and gestational diabetes (pooled OR 1.04 [1.02 to 1.07]). All other pregnancy complications (i.e., gestational hypertension, total pre-eclampsia, eclampsia, placental abruption, and post-partum hemorrhage) tended to be associated with male fetal sex, except for preterm pre-eclampsia, which was more associated with female fetal sex. Overall quality of the included studies was good. Between-study heterogeneity was high due to differences in study population and outcome definition.CONCLUSION: This meta-analysis suggests that the occurrence of pregnancy complications differ according to fetal sex with a higher cardiovascular and metabolic load for the mother in the presence of a male fetus.FUNDING: None.
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Youths in Bolgatanga municipality in the Upper East Region in the rural north of Ghana suffer health and social problems that are caused by their premarital and unsafe sexual behaviour. This study provides more knowledge of and insight into the youths’ conceptions, motives and practices concerning premarital sex in the specific cultural and social context of Bolgatanga municipality. The results of this study can contribute to the development of more effective sexual and reproductive health (SRH) programmes. Interviews with 33 youths and 27 key respondents were carried out. Four repertoires were constructed to present the dynamics wherein the youths’ premarital sexual behaviour takes place. The dominant ideology of abstaining from premarital sex contrasts with the counter ideology of allowing premarital sex, influenced by increasing modernization. SRH programmes should take into account the increasing influence of modernity, gender differences and the compelling influence of peer groups, all of which contribute to youths engaging in premarital sex, with health and social problems as possible consequences. (Afr J Reprod Health 2013; 17[4]: 93-106).
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Background: A positive association between obesity based on body mass index (BMI) and periodontitis has been reported. Fat tissue-related systemic inflammation acts as the link to periodontal comorbidities of obesity. However, the BMI is unable to distinguish fat and fat-free tissues. More precise measures are required to evaluate body composition, including fat and fat-free tissues. This study aimed to determine the sex differences in the association between dual-energy x-ray absorptiometry (DXA)-measured body composition (i.e., fat mass and muscle mass) and phenotypes with periodontitis. Methods: Cross-sectional data of 3892 participants from the National Health and Nutrition Examination Survey (NHANES) study 2011‒2014 were analyzed. Adiposity indices (fat mass index [FMI] and percentage body fat [%BF]) and muscle mass index (MMI) were calculated. The participants were categorized by the quintiles of FMI, MMI, and %BF. Body composition phenotypes were categorized as: low adiposity-low muscle (LA-LM), low adiposity-high muscle (LA-HM), high adiposity-low muscle (HA-LM), or high adiposity-high muscle (HA-HM), respectively. Periodontitis was defined by the CDC/AAP (Centers for Disease Control and Prevention/American Academy of Periodontology) criteria. Multivariable logistic regression analysis was conducted, stratified by sex. We further adjusted for white blood cell (WBC) counts in the sensitivity analysis. Results: Restricted cubic splines revealed non-linear associations between body composition indices and periodontitis risk. Women with a higher FMI (odds ratio for Q5 vs. Q1 [ORQ5vs1] = 1.787, 95% confidence interval: 1.209–2.640) or %BF (ORQ5vs1 = 2.221, 1.509–3.268) had increased odds of periodontitis. In addition, women with HA-LM phenotype were more likely to develop periodontitis (OR = 1.528, 1.037–2.252). Interestingly, the WBC count, a systemic inflammatory biomarker, attenuated these associations. No statistically significant associations were found in men. Conclusions: The association between DXA-measured body composition and phenotypes with periodontitis differs per sex. Only in women higher adiposity indices and HA-LM phenotype were associated with an increased risk of periodontitis.
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Circulating sex hormone levels have been linked to a wide range of cardiovascular risk factors in men, but studies on incident CVD have been inconclusive [1]. Recent data from meta-analyses show an increase in CVD risk with low testosterone in elderly men and no association with estradiol levels [2,3]. To clarify the role of sex hormones in male CVD risk, we examined the cross-sectional and longitudinal associations between endogenous sex hormones and subclinical atherosclerosis in a population-based cohort of middle-aged and older men.
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Background. Recent research has shown that the Fitkids Treadmill Test (FTT) is a valid and reproducible exercise test for the assessment of aerobic exercise capacity in children and adolescents who are healthy. Objective. The study objective was to provide sex- and age-related normative values for FTT performance in children and adolescents who were healthy, developing typically, and 6 to 18 years of age. Design. This was a cross-sectional, observational study. Methods. Three hundred fifty-six children and adolescents who were healthy (174 boys and 182 girls; mean age12.9 years, SD3.7) performed the FTT to their maximal effort to assess time to exhaustion (TTE). The least-mean-square method was used to generate sex- and age-related centile charts (P3, P10, P25, P50, P75, P90, and P97) for TTE on the FTT. Results. In boys, the reference curve (P50) showed an almost linear increase in TTE with age, from 8.8 minutes at 6 years of age to 16.1 minutes at 18 years of age. In girls, the P50 values for TTE increased from 8.8 minutes at 6 years of age to 12.5 minutes at 18 years of age, with a plateau in TTE starting at approximately 10 years of age. Limitations. Youth who were not white were underrepresented in this study. Conclusions. This study describes sex- and age-related normative values for FTT performance in children and adolescents who were healthy, developing typically, and 6 to 18 years of age. These age- and sex-related normative values will increase the usefulness of the FTT in clinical practice.
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At the request of the municipality of Rotterdam, the NGO Stichting Humanitas undertook participatory research on boys and men that do sex work in Rotterdam, the Netherlands. This demographic often goes unnoticed in interventions by public institutions or social work organizations. The research focused on discovering common characteristics and potential vulnerabilities this group faces. Furthermore, it assessed their needs in terms of support and assistance (Van den Dries, Boutsias & Van Oorschot, 2021).Participatory research uses various knowledge sources such as propositional knowledge, practical knowledge, and experiential knowledge in the form of lived experiences (Groot, Haveman & Abma, 2020). The research team employed experiential knowledge of sex work, experiential knowledge of the Rotterdam LGBTIQAP+ queer community, propositional knowledge from the discourse on sex work, and social work research supplemented by practical knowledge from the social work practice of outreach and support to sex workers.It has been known that different forms and interpretations of participatory (action) research exist, where, to a greater or lesser extent, similar principles and practices are followed (Dedding et al., 2020). In this contribution, the researchers focus on the lessons learned in this research project on inclusion and power division. They collectively reflect on the extent to which the perspective of experiential knowledge was maximized, which voices were valued and heard and how power balances were divided. Concepts from Power Literacy by Goodwill (2020) are used as a framework.
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Lichamelijke zwakte is een belangrijk onderdeel van kwetsbaarheid en komt veel voor bij oudere volwassenen. Terwijl vrouwen een hogere prevalentie en een eerder begin van kwetsbaarheid kennen zijn sekseverschillen in de ontwikkeling van lichamelijke zwakte nauwelijks bestudeerd. Daarom hebben we in spieren de veranderingen onderzocht die onderscheid maken tussen fitte en zwakke ouderen voor elk geslacht afzonderlijk. Mannen (n = 28) en vrouwen (n = 26) van 75 jaar en ouder werden gegroepeerd op basis van hun fysieke prestatiecriteria. Er werd gebruik gemaakt van spierbiopten genomen uit de vastus lateralis-spier voor genexpressie- en histologisch onderzoek. Er werden paarsgewijze vergelijkingen gemaakt tussen de sterkste en de zwakste groepen voor elk geslacht afzonderlijk, en potentiële geslachts-specifieke effecten werden beoordeeld. Zwakke vrouwen toonden een hogere expressie van ontstekingsroutes, infiltratie van NOX2-immuuncellen, samen met een hogere VCAM1-expressie. Zwakke mannen werden gekenmerkt door een kleinere diameter van type 2 (snelle) spiervezels en lagere expressie van PRKN. Zwakte-geassocieerde genexpressie-veranderingen in de spieren waren verschillend van veroudering-geassocieerde genexpressie-veranderingen, wat erop wijst dat de pathofysiologie van fysieke zwakte niet noodzakelijkerwijs afhankelijk is van veroudering. We concluderen dat zwakte-geassocieerde veranderingen in de spieren sekse-specifiek zijn. Aanbevolen wordt om bij onderzoek naar kwetsbaarheid rekening te houden met sekseverschillen, omdat deze verschillen een grote impact kunnen hebben over de ontwikkeling van (farmaceutische) interventies tegen kwetsbaarheid.
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When an adult claims he cannot sleep without his teddy bear, people tend to react surprised. Language interpretation is, thus, influenced by social context, such as who the speaker is. The present study reveals inter-individual differences in brain reactivity to social aspects of language. Whereas women showed brain reactivity when stereotype-based inferences about a speaker conflicted with the content of the message, men did not. This sex difference in social information processing can be explained by a specific cognitive trait, one's ability to empathize. Individuals who empathize to a greater degree revealed larger N400 effects (as well as a larger increase in γ-band power) to socially relevant information. These results indicate that individuals with high-empathizing skills are able to rapidly integrate information about the speaker with the content of the message, as they make use of voice-based inferences about the speaker to process language in a top-down manner. Alternatively, individuals with lower empathizing skills did not use information about social stereotypes in implicit sentence comprehension, but rather took a more bottom-up approach to the processing of these social pragmatic sentences.
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Although occupational influences on the wellbeing of social workers have been recognized, influences on the private sexuality or intimate relationship(s) remain unknown. This research addresses how social workers that specialize in offering support to people working in the sex industry, experience impact on their own private sexual lives. The author is a social work practitioner, working with sex workers and victims of human trafficking at NGO Stichting Humanitas in Rotterdam, the Netherlands. Furthermore, she works as a social work teacher and coach at the Amsterdam University of Applied Sciences. After having experienced sexual occupational influences herself, but at the same time having observed a taboo on the topic among colleagues within and outside of the organization, this research topic was chosen. Literature study (presented at SWSexuality16) was followed by interactive model building, an anonymous survey and a focus group. Analysis was largely inductive qualitative with quantitative elements.Results indicate a high prevalence of both positive and negative sexual occupational influences - respectively 87% and 85% - among the practitioners. Regarding positive influences at the intrapersonal level, most commonly the social workers describe that they have become more broad-minded in exploring their own sexuality or sexual behaviour. At interpersonal level the positive influence that was indicated most often was that they are communicating more easily about sexuality with their partner(s). In the area of negative influences at intrapersonal level, the most common influence is the experience that due to the work they occasionally are not in the mood for sexuality or intimacy when they would want to be. At interpersonal level, most often it is described that the social workers feel more distrust towards (the loyalty of) their (future) partner(s).Attention for the topic is considered important for maintaining and improving sustainable employability of the social worker and indirectly the quality of the offered social work services. Although self-care methods are applied, most practitioners do not experience sufficient organizational support to cope with negative sexual occupational influences. They would appreciate acknowledgement for the intensity of this particular type of work and possible sexual occupational influences. Considering the taboo nature of the topic, outreach information and compulsory periodical checks with an external specialist were recommended as possible helpful methods of care for the social worker. The existence of similar impact on the private sexual life is assumed for social workers working in other areas and with other user groups.
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Communal breeding, wherein multiple conspecifics live and reproduce together, may generate short-term benefits in terms of defence and reproduction. However, its carry-over effects remain unclear. We experimentally tested the effects of communal breeding on parental care and reproduction in burying beetles (Nicrophorus vespilloides), which use carcasses as breeding resources and provide parental care to offspring. We subjected individuals to communal or non-communal breeding (i.e. pair breeding) during their first breeding event and to non-communal breeding during their second breeding event. We measured the parental care of individuals and of groups and the reproductive success of groups during both breeding events. In communal groups, large individuals became dominant and largely monopolized the carcass, whereas small individuals (i.e. subordinates) had restricted access to the carcass. At the first breeding event, large males in communal groups spent more time providing care than large males in non-communal groups, whereas such an effect was not observed for large females and small individuals. Reproductive successes were similar in communal and non-communal groups, indicating no short-term benefits of communal breeding in terms of reproduction. Compared with males from non-communal groups, males originating from communal groups produced a larger size of brood during their second breeding event, whereas such an effect was not observed for females. Our results demonstrate the sex-specific effects of communal breeding experience on parenting performance and fitness.
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