http://dx.doi.org/10.14261/postit/2B827A9F-E9C0-4A75-B45C19B59DD1E5AAIn 2015 and 2016, Saxion University of Applied Sciences organized the 2nd and 3rd edition of the Regional Innovation and Entrepreneurship Conference (RIEC).The term entrepreneurialism doesn’t exist. In this paper it is coined to distinguish entrepreneurship from entrepreneurial behaviour by employees. In an serious gaming experiment among Physical Therapy students, we tried to design a learning intervention to advance entrepreneurial behaviour in a non-business setting.