Neighborhood image processing operations on Field Programmable Gate Array (FPGA) are considered as memory intensive operations. A large memory bandwidth is required to transfer the required pixel data from external memory to the processing unit. On-chip image buffers are employed to reduce this data transfer rate. Conventional image buffers, implemented either by using FPGA logic resources or embedded memories are resource inefficient. They exhaust the limited FPGA resources quickly. Consequently, hardware implementation of neighborhood operations becomes expensive, and integrating them in resource constrained devices becomes unfeasible. This paper presents a resource efficient FPGA based on-chip buffer architecture. The proposed architecture utilizes full capacity of a single Xilinx BlockRAM (BRAM36 primitive) for storing multiple rows of input image. To get multiple pixels/clock in a user defined scan order, an efficient duty-cycle based memory accessing technique is coupled with a customized addressing circuitry. This accessing technique exploits switching capabilities of BRAM to read 4 pixels in a single clock cycle without degrading system frequency. The addressing circuitry provides multiple pixels/clock in any user defined scan order to implement a wide range of neighborhood operations. With the saving of 83% BRAM resources, the buffer architecture operates at 278 MHz on Xilinx Artix-7 FPGA with an efficiency of 1.3 clock/pixel. It is thus capable to fulfill real time image processing requirements for HD image resolution (1080 × 1920) @103 fcps.
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Background: The emergence of smartphones and wearable sensor technologies enables easy and unobtrusive monitoring of physiological and psychological data related to an individual’s resilience. Heart rate variability (HRV) is a promising biomarker for resilience based on between-subject population studies, but observational studies that apply a within-subject design and use wearable sensors in order to observe HRV in a naturalistic real-life context are needed. Objective: This study aims to explore whether resting HRV and total sleep time (TST) are indicative and predictive of the within-day accumulation of the negative consequences of stress and mental exhaustion. The tested hypotheses are that demands are positively associated with stress and resting HRV buffers against this association, stress is positively associated with mental exhaustion and resting HRV buffers against this association, stress negatively impacts subsequent-night TST, and previous-evening mental exhaustion negatively impacts resting HRV, while previous-night TST buffers against this association. Methods: In total, 26 interns used consumer-available wearables (Fitbit Charge 2 and Polar H7), a consumer-available smartphone app (Elite HRV), and an ecological momentary assessment smartphone app to collect resilience-related data on resting HRV, TST, and perceived demands, stress, and mental exhaustion on a daily basis for 15 weeks. Results: Multiple linear regression analysis of within-subject standardized data collected on 2379 unique person-days showed that having a high resting HRV buffered against the positive association between demands and stress (hypothesis 1) and between stress and mental exhaustion (hypothesis 2). Stress did not affect TST (hypothesis 3). Finally, mental exhaustion negatively predicted resting HRV in the subsequent morning but TST did not buffer against this (hypothesis 4). Conclusions: To our knowledge, this study provides first evidence that having a low within-subject resting HRV may be both indicative and predictive of the short-term accumulation of the negative effects of stress and mental exhaustion, potentially forming a negative feedback loop. If these findings can be replicated and expanded upon in future studies, they may contribute to the development of automated resilience interventions that monitor daily resting HRV and aim to provide users with an early warning signal when a negative feedback loop forms, to prevent the negative impact of stress on long-term health outcomes.
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Ook met meer eigen vermogen worden verliezen bij banken uiteindelijk door 'de samenleving' gedragen.
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Hogere kapitaaleisen voor banken zijn geen garantie voor een lager operationeel risico.
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David van Overbeek (De Nieuwe Wereld) in gesprek met lector New Finance en mede-oprichter van Stichting Ons Geld Martijn Jeroen van der Linden. “Als je een veilige haven creëert voor geld dan worden banken gedwongen zich verantwoorder te financieren.” Van der Linden houdt zich bezig met de toekomst van ons geldstelsel. Daartoe heeft hij enkele jaren geleden ‘Ons Geld’ opgericht. “Ik probeer met de stichting Ons Geld al langer dit onderwerp op de politieke agenda te zetten.” Dat is van groot belang, zo stelt Van der Linden. “De inrichting van het geldstelsel is bepalend voor de inrichting van de economie, en misschien wel van de hele maatschappij.” In dit gesprek vertelt Van der Linden dat in de jaren na de financiële crisis van 2008 nauwelijks een fundamentele discussie over het systeem als geheel is gevoerd. Het ging vaak over details, zoals exorbitante beloningen en de buffers van banken, maar de fundamenten werden naar zijn smaak te weinig in vraag gesteld. “Eigenlijk zouden we het systeem zelf moeten bediscussiëren, op een niveau hoger. Wie zouden er in deze wereld geld moeten of mogen creëren? [..] Waarom is dat geen publieke taak?” Onder andere in z’n position paper dat hij afgelopen jaar schreef, zet Van der Linden de kernzaken van een nieuw systeem uiteen. Hij pleit voor geldscheppende centrale banken, digitaal geld in publieke vorm en het liberaliseren en dereguleren van banken. “Als je een veilige haven creëert voor geld dan worden banken gedwongen zich verantwoorder te financieren.” Dat is volgens Van der Linden evenwel geen eenvoudige taak. “Het moeilijkste is om het politiek te maken. Er [moet] in de Tweede Kamer en het Europarlement een debat gevoerd worden over hoe we wij ons financiële en monetaire stelsel willen inrichten in het digitale tijdperk.”
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The purpose of this study is to investigate the impact that unevenly allocating buffer capacity has on throughput and average buffer level regarding unreliable lines to better understand the relevant factors in supply chain design. Results show that the best patterns for unreliable merging lines in terms of generating higher throughput rates (TR), as compared to a balanced merging line counterpart, are those where total available buffer capacity is allocated between workstations in either an inverted bowl pattern (i.e. concentrating buffer capacity towards the centre of the line), or a balanced line pattern. In contrast, when considering the trade-off between generating revenue resulting from TR and reducing cost created by average buffer levels (ABL), we found that the balanced pattern was not the best pattern. The best pattern was dependent on the length of the line and on the total buffer capacity as shorter lines with very constrained buffers were best served with an inverted bowl pattern while longer lines had the best results when applying an ascending buffer allocation pattern. Longer lines, in contrast, had the best results regarding the trade-off between TR and ABL, on average, by allocating buffer capacity evenly in one of the parallel lines while applying any other pattern in the remaining parallel line.
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Background: The purpose of this study is to increase our understanding of environmental correlates that are associated with route choice during active transportation to school (ATS) by comparing characteristics of actual walking and cycling routes between home and school with the shortest possible route to school. Methods: Children (n = 184; 86 boys, 98 girls; age range: 8–12 years) from seven schools in suburban municipalities in the Netherlands participated in the study. Actual walking and cycling routes to school were measured with a GPS-device that children wore during an entire school week. Measurements were conducted in the period April–June 2014. Route characteristics for both actual and shortest routes between home and school were determined for a buffer of 25 m from the routes and divided into four categories: Land use (residential, commercial, recreational, traffic areas), Aesthetics (presence of greenery/natural water ways along route), Traffic (safety measures such as traffic lights, zebra crossings, speed bumps) and Type of street (pedestrian, cycling, residential streets, arterial roads). Comparison of characteristics of shortest and actual routes was performed with conditional logistic regression models. Results: Median distance of the actual walking routes was 390.1 m, whereas median distance of actual cycling routes was 673.9 m. Actual walking and cycling routes were not significantly longer than the shortest possible routes. Children mainly traveled through residential areas on their way to school (>80 % of the route). Traffic lights were found to be positively associated with route choice during ATS. Zebra crossings were less often present along the actual routes (walking: OR = 0.17, 95 % CI = 0.05–0.58; cycling: OR = 0.31, 95 % CI = 0.14–0.67), and streets with a high occurrence of accidents were less often used during cycling to school (OR = 0.57, 95 % CI = 0.43–0.76). Moreover, percentage of visible surface water along the actual route was higher compared to the shortest routes (walking: OR = 1.04, 95 % CI = 1.01–1.07; cycling: OR = 1.03, 95 % CI = 1.01–1.05). Discussion: This study showed a novel approach to examine built environmental exposure during active transport to school. Most of the results of the study suggest that children avoid to walk or cycle along busy roads on their way to school. https://doi.org/10.1186/s12966-016-0373-y
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Met meer eigen vermogen voor banken loopt u minder risico als belastingbetaler maar meer in een andere gedaante.
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Lean Production (LP) can be regarded as a design approach in search of a theoretical foundation. In this paper we show that Lowlands’ Sociotechnical Design Theory (STSL) could function as such a foundation. To reach this goal, we first describe STSL as a system theoretical reformulation of Original Sociotechnical Theory (OSTS). Then, we introduce the Toyota Production System as the origin of LP and the challenge it poses for the academic field of organization design. This academic field should (1) assess LP’s success, (2) generalize it by embedding it in more abstract concepts and theories in order to be able to (3) re-specify it for different manufacturing and non-manufacturing contexts. Next, we give an exposition of STSL as a structural design approach based on developments in system theory. At last, we reformulate lean production in STSL terms and so show that LP is a subcase within the more general theory of STSL. We discuss the merits of both approaches and clarify some misunderstandings of lean both outside and inside the lean community. Embedding LP in the more general language of STSL should enable us to discover similarities and differences, to start a process of mutual learning, to integrate diverse design approaches in a theory of organizational design and to add content to redesign proposals of for example the health care system as proposed by Porter and Teisberg (2006) and Christensen et al. (2009). We quote extensively from the lean literature (to convince our sociotechnical friends) and embed both STSL and LP in the broader literature on organization design. We hope this adds a new perspective to the one given in the Operations Management literature on LP. Again, mutual learning is the goal.
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from the article: "Abstract: The oral mucosa is the first immune tissue that encounters allergens upon ingestion of food. We hypothesized that the bio-accessibility of allergens at this stage may be a key determinant for sensitization. Light roasted peanut flour was suspended at various pH in buffers mimicking saliva. Protein concentrations and allergens profiles were determined in the supernatants. Peanut protein solubility was poor in the pH range between 3 and 6, while at a low pH (1.5) and at moderately high pHs (>8), it increased. In the pH range of saliva, between 6.5 and 8.5, the allergens Ara h2 and Ara h6 were readily released, whereas Ara h1 and Ara h3 were poorly released. Increasing the pH from 6.5 to 8.5 slightly increased the release of Ara h1 and Ara h3, but the recovery remained low (approximately 20%) compared to that of Ara h2 and Ara h6 (approximately 100% and 65%, respectively). This remarkable difference in the extraction kinetics suggests that Ara h2 and Ara h6 are the first allergens an individual is exposed to upon ingestion of peanut-containing food. We conclude that the peanut allergens Ara h2 and Ara h6 are quickly bio-accessible in the mouth, potentially explaining their extraordinary allergenicity."
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