STUDY DESIGN: Meta-analysis.OBJECTIVES: To define the accuracy of clinical tests for assessing anterior cruciate ligament (ACL) ruptures.BACKGROUND: The cruciate ligaments, and especially the ACL, are among the most commonly injured structures of the knee. Given the increasing injury prevalence, there is undoubtedly a growing need for clinical decision making of health care providers. We reviewed the literature to analyze the diagnostic accuracy of the clinical examination for assessing ACL ruptures.METHODS AND MEASURES: MEDLINE (1966 to April 2005), EMBASE (1989 to April 2005), and CINAHL (1982 to April 2005) searches were performed. Also reference lists of the included studies were reviewed. Studies selected for data extraction were those that addressed the accuracy of at least 1 physical diagnostic test for ACL rupture and compared the performance of the clinical examination of the knee with a reference standard, such as arthroscopy, arthrotomy, or MRI. Searching was limited to English, German, and Dutch languages.RESULTS: Twenty-eight studies that assessed the accuracy of clinical tests for diagnosing ACL ruptures met the inclusion criteria. Study results were, however, heterogeneous. The Lachman test is the most valid test to determine ACL tears, showing a pooled sensitivity of 85% (95% confidence interval [CI], 83-87) and a pooled specificity of 94% (95% CI, 92-95). The pivot shift test is very specific, namely 98% (95% CI, 96-99), but has a poor sensitivity of 24% (95% CI, 21-27). The anterior drawer test shows good sensitivity and specificity in chronic conditions, respectively 92% (95% CI, 88-95) and 91% (95% CI, 87-94), but not in acute conditions.CONCLUSION: In case of suspected ACL injury it is recommended to perform the Lachman test. Because the pivot shift test is very specific both in acute as well as in chronic conditions, it is recommended to perform the pivot shift test as well.
DOCUMENT
In this review article, the authors contextualize the contemporary practice of medical tourism in terms of the concept of worldmaking, which was introduced (in this journal) with two articles a year or two ago by Hollinshead. Here, the authors first contextualize medical tourism in terms of "worldmaking" per medium of the observations of the corporeal realms identified by Alexis de Tocqueville almost 200 years ago. In 1835, de Tocqueville wrote with enthusiasm tinged with nostalgic regret about the new world of American democracy that he then saw as the world of the future. A serious rupture in history took place of which he became a most relevant critic. But there have been (according to Mainil, Platenkamp, and Meulemans) many ruptures since then: that is, there have been short periods of "in-between worlds" that became ever more anchored in the timeline of Western history. Today, they argue that tourism as a field of expertise, practice, and knowledge is intertwined with several other networks of expertise. It is responsible (itself) for many small "ruptures" in these modern times. Mass tourism can be seen as such a shift. Sustainable tourism and the attention paid to climate change would be another such shift. And the authors of this review argue that an interesting and deep-seated case in this regard is medical tourism. They argue here that medical tourism has a great deal of worldmaking capacity, especially by means of the Internet and international marketing tools. It arises in the interstices of the interacting networks of a global world. It crosses borders in line with emerging power structures in a global network, but it also meets local resistance or regional obstacles that are related to other networks. In between these worlds of human experience, various interactions of perspectives on the concept of health itself come to the surface. Within the field of medical tourism different stakeholders play a role in a worldmaking process. Our reviewers from the Low Countries thereby argue that medical tourism itself is responsible for a Tocquevillean rupture within and across our global network society. In their view, medical tourism also constitutes a new hybrid-that is, as a hybrid medical paradigm that seems to be appearing within the performative and productive world of tourism.
MULTIFILE
Objective Primary to provide an overview of diagnostic accuracy for clinical tests for common elbow (sport) injuries, secondary accompanied by reproducible instructions to perform these tests. Design A systematic literature review according to the PRISMA statement. Data sources A comprehensive literature search was performed in MEDLINE via PubMed and EMBASE. Eligibility criteria We included studies reporting diagnostic accuracy and a description on the performance for elbow tests, targeting the following conditions: distal biceps rupture, triceps rupture, posteromedial impingement, medial collateral ligament (MCL) insufficiency, posterolateral rotatory instability (PLRI), lateral epicondylitis and medial epicondylitis. After identifying the articles, the methodological quality was assessed using the QUADAS-2 checklist. Results Our primary literature search yielded 1144 hits. After assessment 10 articles were included: six for distal biceps rupture, one for MCL insufficiency, two for PLRI and one for lateral epicondylitis. No articles were selected for triceps rupture, posteromedial impingement and medial epicondylitis. Quality assessment showed high or unclear risk of bias in nine studies. We described 24 test procedures of which 14 tests contained data on diagnostic accuracy. Conclusions Numerous clinical tests for the elbow were described in literature, seldom accompanied with data on diagnostic accuracy. None of the described tests can provide adequate certainty to rule in or rule out a disease based on sufficient diagnostic accuracy.
LINK
The anterior cruciate ligament (ACL) is a strong rope-like tissue which connects the femur to the tibia in the knee joint. Its function is to provide structural stability to the knee while preventing unnatural forward movement of the tibia relative to the femur. Acute complete ACL ruptures during movements like knee hyperextension or sudden changes of direction (pivoting) damage two entities: the ligament itself and its nerve connections to the posterior tibial nerve (PTN). PTN innervation in the ACL is essential for: a) proprioception (e.g. perception of position and movement/acceleration experienced by the ligament), and b) stability of the knee joint. Upon ACL rupture, the orthopedic surgeon reconstructs the ACL with a graft from the hamstring, patellar or quadriceps tendon. After the surgery, the goal is to regain neuromuscular control and dynamic stabilization during rehabilitation as soon as possible for a quick return to sports and daily activities. However, surgeons are not able to reconstruct the nerve gap between the PTN and the grafted ligament due to the microscopic size of the innervation in the ACL. Not linking the PTN to the graft creates a disconnection between the knee joint and the spinal cord. To mitigate these disadvantages in ACL surgery, this study focuses on activating the growth of proprioception nerve endings using a ligament loaded with growth factors (neurotrophins). We hypothesize that neurotrophins will activate proprioceptive fibers of neurons close to the ACL. We describe graft fabrication steps and in vitro experiments to expand on the regeneration capacity of a commercially available ACL-like synthetic ligament called LARS. The results will bring the ACL regeneration field closer to having a graft that can aid patients in regaining mobility and stability during locomotion and running, confidence in the strength of the knee joint, and quick return to sports.
Bij veel (sport)blessures en orthopedische aandoeningen, zoals voorste kruisband (VKB-) rupturen en enkelfracturen, moeten patiënten na een operatieve ingreep een lang revalidatietraject ondergaan. Fysiotherapeuten, (mentale) coaches, inspanningsfysiologen en orthopedisch chirurgen constateren dat patiënten ondanks goede begeleiding veelal hun fysieke niveau van voor de blessure niet meer bereiken. Om kwalitatief betere zorg te kunnen bieden, willen deze professionals meer inzicht krijgen in het individuele herstel. Door een combinatie van lichamelijke en psychologische parameters intensief te monitoren, denken zij namelijk eerder de therapie aan te kunnen passen op (on)gewenste veranderingen in het beloop van herstel. De zorgprofessionals hebben echter onvoldoende tijd en mogelijkheden om patiënten intensief te monitoren. Bovendien denken zij het herstel verder te kunnen ondersteunen door patiënten zelf te laten meten omdat patiënten meer verantwoordelijkheid voor hun gezondheid nemen indien zij toegang krijgen tot hun eigen data. De zorgprofessionals vragen zich daarom af hoe zij een zelf-monitoringsysteem voor orthopedische patiënten kunnen inrichten, dat hen in staat stelt therapie op maat te geven gedurende het totale revalidatieproces (casus VKB-reconstructies). Centrale onderzoeksvraag is: Welke kennis en vaardigheden hebben zorgprofessionals en patiënten na een VKB-reconstructie nodig om een zelf-monitoringsysteem slim toe te kunnen passen in de zorgpraktijk? Deze onderzoeksvraag kent de volgende deelvragen: A. Hoe moet een zelf-monitoringsysteem volgens zorgprofessionals, technici/ontwerpers en patiënten worden ingericht en gebruikers getraind om de patiënten na een VKB-reconstructie in staat te stellen een kernset van lichamelijke en psychologische parameters zelfstandig te verzamelen en te delen? B. Hoe wordt het zelf-monitoringsysteem door zorgprofessionals en patiënten na een VKB-reconstructie in de praktijk gebruikt en hoe staat het gebruik in relatie tot herstel? C. Wat zijn de ervaringen van zowel de zorgprofessionals als patiënten na een VKB-reconstructie met het zelf-monitoringsysteem en wat zijn de belemmerende en/of bevorderende factoren bij het gebruik van het zelf-monitoringsysteem voor het revalidatietraject?