No clinical characteristics, particularly not sputum characteristics, can guide antibiotic prescription in patients with mild to severe COPD exacerbations
Background: Patients with chronic obstructive pulmonary disease (COPD) demonstrate reduced levels of daily physical activity (DPA) compared to healthy controls. This results in a higher risk of hospital admission and shorter survival. Performing regular DPA reduces these risks. Objective: To develop an eHealth intervention that will support patients with COPD to improve or maintain their DPA after pulmonary rehabilitation. Methods: The design process consisted of literature research and the iterative developing and piloting phases of the Medical Research Council (MRC) model for complex clinical interventions and the involvement of end users. Participants were healthy adults and persons with COPD. Results: The mobile phone interface met all the set requirements. Participants found that the app was stimulating and that reaching their DPA goals was rewarding. The mean (SD) scores on a 7-point scale for usability, ease of use, ease of learning, and contentment were 3.8 (1.8), 5.1 (1.1), 6.0 (1.6), and 4.8 (1.3), respectively. The mean (SD) correlation between the mobile phone and a validated accelerometer was 0.88 (0.12) in the final test. The idea of providing their health care professional with their DPA data caused no privacy issues in the participants. Battery life lasted for an entire day with the final version, and readability and comprehensibility of text and colors were favorable. Conclusions: By employing a user-centered design approach, a mobile phone was found to be an adequate and feasible interface for an eHealth intervention. The mobile phone and app are easy to learn and use by patients with COPD. In the final test, the accuracy of the DPA measurement was good. The final version of the eHealth intervention is presently being tested by our group for efficacy in a randomized controlled trial in COPD patients.
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In 2019, The Global Initiative for Chronic Obstructive Lung Disease (GOLD) modified the grading system for patients with COPD, creating 16 subgroups (1A–4D). As part of the COPD Cohorts Collaborative International Assessment (3CIA) initiative, we aim to compare the mortality prediction of the 2015 and 2019 COPD GOLD staging systems. We studied 17 139 COPD patients from the 3CIA study, selecting those with complete data. Patients were classified by the 2015 and 2019 GOLD ABCD systems, and we compared the predictive ability for 5-year mortality of both classifications. In total, 17139 patients with COPD were enrolled in 22 cohorts from 11 countries between 2003 and 2017; 8823 of them had complete data and were analysed. Mean±SD age was 63.9±9.8 years and 62.9% were male. GOLD 2019 classified the patients in milder degrees of COPD. For both classifications, group D had higher mortality. 5-year mortality did not differ between groups B and C in GOLD 2015; in GOLD 2019, mortality was greater for group B than C. Patients classified as group A and B had better sensitivity and positive predictive value with the GOLD 2019 classification than GOLD 2015. GOLD 2015 had better sensitivity for group C and D than GOLD 2019. The area under the curve values for 5-year mortality were only 0.67 (95% CI 0.66–0.68) for GOLD 2015 and 0.65 (95% CI 0.63–0.66) for GOLD 2019. The new GOLD 2019 classification does not predict mortality better than the previous GOLD 2015 system.
AANLEIDING Mensen met Chronic Obstructive Pulmonary Disease (COPD) hebben vaak langdurig fysiotherapie nodig. Symptomen zoals kortademigheid en vermoeidheid, veelal in combinatie met beperkte gezondheidsvaardigheden (46%), beïnvloeden hun leven sterk. Persoonsgerichte zorg is afgestemd op iemands persoonlijke behoeften, wensen en voorkeuren. Dit vereist dat fysiotherapeuten zinvol gebruik maken van meetresultaten. Zinvol betekent meetresultaten integreren in het zorgproces, deze communiceren op een begrijpelijke manier voor de patiënt, om samen te beslissen en zodoende tot persoonsgerichte zorg te komen. Echter, fysiotherapeuten vinden het lastig om meetresultaten zinvol te gebruiken in het zorgproces en de ervaren meerwaarde van gebruik van meetresultaten is beperkt. In de dagelijkse praktijk ontbreekt het fysiotherapeuten aan praktische handvatten om meetresultaten zinvoller te gebruiken ten behoeve van verdere personalisatie van fysiotherapeutische zorg. DOEL Het bevorderen van inzicht, kennis, vaardigheden en attitude van fysiotherapeuten in het zinvol gebruiken van meetresultaten voor patiënten met COPD. Dit willen we bereiken door: • Praktische handvatten voor zinvol gebruik van meetresultaten, wat leidt tot een transparanter, efficiënter en effectiever zorgproces. • Een verschuiving naar meer persoonsgerichte zorg, waarbij patiënten actief betrokken worden bij hun zorgproces en ongelijkheid in zorg wordt verminderd. CONSORTIUM Zuyd Hogeschool, Hogeschool Utrecht, Amsterdam UMC, LUMC, Nivel, Chronisch ZorgNet, KNGF, Longfonds, Mens Achter de Patiënt, 7 eerstelijns fysiotherapiepraktijken. ONDERZOEKSPLAN De doelstellingen worden gerealiseerd met een mixed methods design met vier, onderling samenhangende, werkpakketten (WP) met elk een specifieke focus. WP1: Verdiepend inzicht (maand 1-12) WP2: Handvatten selecteren en (door)ontwikkelen met de praktijk (maand 1-13) WP3: Handvatten testen met de praktijk (maand 13-20) WP4: Disseminatie (maand 13-24) RELEVANTIE Dit project is relevant omdat eerstelijns fysiotherapeuten beter toegerust worden om meetresultaten zinvol te kunnen gebruiken voor persoonsgerichte zorg bij patiënten met COPD. In het verlengde daarvan dragen ze bij aan het verminderen van ongelijkheid in zorg, betere gezondheidsuitkomsten en meer patiënttevredenheid.
