With the increasing number of proton therapy centers worldwide, particularly in Europe, proton therapy is becoming a more established treatment option. However, education and guidelines, specifically tailored to radiation therapists (RTTs) and dosimetrists, are lacking. Through the “Towards a Sustainable RTT Network” (TaSeRnet) project, efforts are underway to harmonize proton therapy practices among RTTs and dosimetrists across Europe. This scoping review aims to identify and summarize existing guidelines relevant to RTTs and dosimetrists working in proton therapy, providing a necessary first step toward the future development of specific guidelines and education for these professions. Ten articles were identified that include guidelines covering certain aspects of proton therapy workflows in several clinical indications. However, significant gaps remain regarding the specific tasks performed by RTTs and dosimetrists. In particular, no guidelines were found addressing treatment execution, a workflow typically performed by RTTs. Moreover, the limited involvement of RTTs and dosimetrists in the development of existing guidelines may result in the exclusion of essential practical knowledge and expertise. As they play a critical role in the daily delivery of proton therapy, their input is vital to ensure comprehensive and applicable guidelines. In conclusion, this review underscores the need for developing guidelines specifically for RTTs and dosimetrists in collaboration with the broader multidisciplinary team. Developing such guidelines will support the standardization of clinical practice and contribute to improved quality of care.
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Abstract Background: We studied the relationship between trismus (maximum interincisor opening [MIO] ≤35 mm) and the dose to the ipsilateral masseter muscle (iMM) and ipsilateral medial pterygoid muscle (iMPM). Methods: Pretreatment and post-treatment measurement of MIO at 13 weeks revealed 17% of trismus cases in 83 patients treated with chemoradiation and intensity-modulated radiation therapy. Logistic regression models were fitted with dose parameters of the iMM and iMPM and baseline MIO (bMIO). A risk classification tree was generated to obtain optimal cut-off values and risk groups. Results: Dose levels of iMM and iMPM were highly correlated due to proximity. Both iMPM and iMM dose parameters were predictive for trismus, especially mean dose and intermediate dose volume parameters. Adding bMIO, significantly improved Normal Tissue Complication Probability (NTCP) models. Optimal cutoffs were 58 Gy (mean dose iMPM), 22 Gy (mean dose iMM) and 46 mm (bMIO). Conclusions: Both iMPM and iMM doses, as well as bMIO, are clinically relevant parameters for trismus prediction.
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OBJECTIVE: The objective was to assess swallowing, mouth opening and speech function during the first year after radiation-based treatment (RT(+)) after introduction of a dedicated preventive rehabilitation program for stage III-IV oropharyngeal carcinoma (OPC).METHODS: Swallowing, mouth opening and speech function were collected before and at six- and twelve-month follow-up after RT(+) for OPC as part of ongoing prospective assessments by speech-language pathologists .RESULTS: Objective and patient-perceived function deteriorated until 6 months and improved until 12 months after treatment, but did not return to baseline levels with 25%, 20% and 58% of the patients with objective dysphagia, trismus and speech problems, respectively. Feeding tube dependency and pneumonia prevalence was low.CONCLUSION: Despite successful implementation, a substantial proportion of patients still experience functional limitations after RT(+) for OPC, suggesting room for improvement of the current rehabilitation program. Pretreatment sarcopenia seems associated with worse functional outcomes and might be a relevant new target for rehabilitation strategies.
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