The Amsterdam Deysselbuurt, part of Nieuw-West, is undergoing major renovations and demolition/rebuild for the coming 10 years. Together with Rochdale, de Gemeente Amsterdam and other partners, the Robot Lab works on a case study to work towards (temporarily) urban structures, created from wood from the renovations, together with tenants. In Spring 2023, students and teachers from the Minor 'Robotic Production and Circular Materials' worked on the design and build of a first 'conversation piece'. This prototype construction was made from waste wood, harvested by wood industry partner Helwig during window replacements.
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Objective: To systematically describe changes in pain and functioning in patients with osteoarthritis (OA) awaiting total joint replacement (TJR), and to assess determinants of this change. Methods: MEDLINE®, EMBASE, CINAHL® and Cochrane Database were searched through June 2008. The reference lists of eligible publications were reviewed. Studies that monitored pain and functioning in patients with hip or knee OA during the waiting list for TJR were analyzed. Data were collected with a pre-specified collection tool. Methodological quality was assessed and a best-evidence analysis was performed to summarize results. Results: Fifteen studies, of which two were of high quality, were included and involved 788 hip and 858 knee patients (mean age 59-72 and main wait 42-399 days). There was strong evidence that pain (in hip and knee OA) and self-reported functioning (in hip OA) do not deteriorate during a
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Objective: To explore the nature and extent of possible residual complaints among Dutch hypothyroid patients using thyroid replacement therapy, we initiated a comprehensive study measuring health-related quality of life (QoL), daily functioning, and hypothyroidism-associated symptoms in patients and control persons. Methods: An online survey measuring thyroid-specific QoL (ThyPRO), daily functioning, and hypothyroidismassociated symptoms (ThySHI) was distributed among treated hypothyroid patients and control individuals. The advertising text was formulated in an open-ended manner. Patients also provided their most recent thyroid blood values and their thyroid medication. Results: There was a large-sized impairment of QoL (Cohen’s d = 1.04, +93 % ThyPRO score) in hypothyroid patients on thyroid replacement therapy (n = 1195) as compared to controls (n = 236). Daily functioning was significantly reduced i.e., general health (-38 %), problems with vigorous- (+64 %) and moderate activities (+77 %). Almost 80 % of patients reported having complaints despite thyroid medication and in-range thyroid blood values, with 75 % expressing a desire for improved treatment options for hypothyroidism (total n = 1194). Hypothyroid patients experienced 2.8 times more intense hypothyroidism-associated symptoms than controls (n = 865, n = 203 resp). Patients’ median reported serum concentrations were: TSH 0.90 mU/L, FT4 17.0 pmol/L, and FT3 2.67 pmol/L, with 52 % having low T3 levels (<3.1 pmol/L). The QoL was not found to be related to age, sex, BMI, menopausal status, stress, serum thyroid parameters, the origin and duration of hypothyroidism, the type of thyroid medication, or the LT4 dose used. Conclusions: Our study revealed major reductions in quality of life and daily functioning, and nearly three times more intense hypothyroidism-associated symptoms in treated hypothyroid patients as compared to controls, despite treatment and largely in-range serum TSH/FT4 concentrations. The QoL was not associated with serum thyroid parameters. We recommend future research into the origin of persisting complaints and the development of improved treatment modalities for hypothyroidism.
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This proposal is directed at the creation of sustainable embedding and preservation methods for biomaterials, in particular those incorporating structural colours (SCs). SCs use the interaction of light with highly ordered, nanostructured materials to generate colour. SCs are intense, angle dependent, can be polarized, non-fading and non-toxic; all characteristics with advantages over pigments. SCs can be created from bacteria, are widely found in nature and offers a route to the creation of high-performance biobased materials: i.e. ‘green’ replacements for dyes. However, naturally derived structural coloured biomaterials, particularly bacteria, require preservation or embedding – an essential step in developing durable products. The current embedding agent is an epoxy resin which is not a sustainable reagent. Indeed, there is a wider need for thermoset matrix materials and other polymers that are more environmentally friendly yet with good performance and cost. In this proposal we will develop such matrix materials using bacterial SCs as a test case and the primary application.
The Hospitality, Tourism, Innovation & Technology Experts Network (HTIT-EN) is a pivotal initiative aimed at unlocking societal impact potential. The Dutch hospitality and tourism sector, which employs over half a million individuals and annually hosts more than 40 million guests, ranks as the Netherlands’ 8th largest economic sector. However, this sector faces numerous challenges, including the uncertain impact of emerging technologies and issues such as unethical behavior, workforce attrition, and staff shortages, which have been exacerbated by the COVID-19 pandemic. The advent of emerging technologies like service robots, immersive experiences, and artificial intelligence has brought the sector to a critical juncture. These innovations pose significant disruptions, challenging the traditional concept of hospitality and questioning the positive societal impact in terms of ethical considerations, inclusivity, affordability, and data privacy.Strategically positioned to address these challenges, HTIT-EN focuses on leveraging emerging technologies to create impactful scenarios and shape the future of hospitality and tourism. Our motivation stems from the sector’s societal importance and its continuous influence on our daily lives. By harnessing technology and innovation, we aim to tackle industry-specific issues and extend the positive societal impact to related human-centered service industries.The overarching mission of HTIT-EN is to empower the Dutch Hospitality and Tourism sector to serve as a driving force for technology-enabled societal impact. The primary objective is to align research activities and promote collaboration. Key objectives include bringing together leading professors specializing in technology-driven impact within the hospitality and tourism sector, initiating research projects in line with a shared research agenda and in collaboration with local and international industry partners, and collaboratively developing expertise in emerging technologies that empower the role of hospitality and tourism as catalysts for societal impact. This endeavor contributes to the development and acceleration of the Knowledge and Innovation Agenda (KIA) ‘Key technologies’ & ‘Digitalization’. The aim is to foster an excellent reputation for Dutch hospitality and tourism as a global leader in technology-driven societal impact.We have strong support from CELTH, the Centre of Expertise within the domain of leisure, tourism and hospitality for the overall ambitions of the research project.Societal issueThe HTIT-EN project bridges societal importance and cross-cutting issues in the tourism and hospitality sectors. It’s fueled by the ambition to leverage emerging technologies to tackle industry-specific challenges, including knowledge and skills gaps, labor shortages and replacements, and evolving consumer expectations.Benefit to societyThe platform brings together professors and researchers from MBO, HBO and WO knowledge institutes as well as diverse set of professional partners to stimulate collaboration, align research lines and establish joint a joint research agenda on how technology-driven impact may become a catalyst within hospitality and tourism.
