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Final market system maps - assessments of barriers to WATERMINING technologies and how to clear these

The WATERMINING project aims to bring solutions to improve the circularity of water treatment and the resulting by-products of these processes. Achieving a deep understanding of the barriers potentially hindering the development of circular water solutions is crucial to design policies that enable the deployment of these techniques. To do this, the WATERMINING project organizes Communities of Practice (CoPs), where stakeholders from the WATERMINING case study projects analysed these market barriers and proposal (policy) measures to clear these.CoPs in the case studies of Lampedusa in Italy and Almería in Spain focused on sea water desalination. The case studies of Faro-Olhão in Portugal, Larnaca in Cyprus and La Llagosta in Spain have been discussed by CoP stakeholders in terms of barriers in circular urban wastewater treatment. The CoP in the Netherlands focused on circular industrial waste water treatment at the Westlake plant at Rotterdam. The barriers defined by the stakeholders in the CoPs were discussed by the WATERMINING partners at the consortium meeting in Palermo (Italy, September 2022), and presented at the WATERMINING Market and Policy workshop in Brussels (Belgium, February 2023).Addressing the three above-mentioned categories of circular water solutions, common barriers identified across all WATERMINING’s case studies are the following. First, stakeholders report a lack of incentives to implement circular solutions, as mainstream linear practices are generally cheaper.This could be addressed by de-encouraging linear techniques by making the disposal of their byproducts (such as brine) more expensive. Another solution could be to provide added value to circular solutions through the monetization of their additional products and services. Subsidies can support in lowering production costs or prices of materials recovered from sea- and wastewater treatment to level the playing field with conventionaly derived material.Another commonly mentioned barrier is the difficulty to introduce products obtained from circular water treatment in the market, both because of a lack of public acceptance and legal constraints stemming from products being regarded as waste. Information campaigns and the revision of current regulatory frameworks to allow these products entering the market would expand the revenue sources from these techniques and improve the circularity of the system. Standardising the circular water treatment technologies in the market could support this, whereby best available techniques reference documents of the EU (BREFs) could be an effective instrument, especially when tapping into an ongoing BREF writing or updating process.Across the case studies and replication studies it has been mentioned that current legislation in case study countries exclude ‘watermined’ products from food and/or other applications. Criteria for endof-waste status of ‘watermined’ products, which would determine whether a product, such as Kaumera which is produced from urban wastewater treatment, is eligible as a fertiliser in agriculture, are usually determined at the level of the EU, but Member States could interpret these more stringently (Member State-level criteria cannot be weaker than the EU-level ones). In this respect it has been recommended to enhance knowledge exchange across Member States, e.g., by creating anEU-based unit (or competencies within an existing unit) to promote cooperation among EU Member States and regional authorities concerning the production, sale and use of products recovered from wastewater treatment.Another common perception stakeholders report is the widespread conservatism in the water sector. Water treatment actors traditionally have a focus on purifying water and supplying this to the market. Generating products from waste streams is often something that market actors are less familiar with. Among other solutions, the ‘Dutch model’ has been recommended as a way to create national centres for the development of knowledge and technology for water management, which would serve as an R&D accelerator.

Regulation in Europe after the financial crisis: patterns of up-loading and down-loading of regulatory solutions

Improved Efficacy of Oral Immunotherapy Using Non-Digestible Oligosaccharides in a Murine Cow's Milk Allergy Model

From teh UU repository: "Background: Oral immunotherapy (OIT) is a promising therapeutic approach to treat food allergic patients. However, there are some concerns regarding its safety and long-term efficacy. The use of non-digestible oligosaccharides might improve OIT efficacy since they are known to directly modulate intestinal epithelial and immune cells in addition to acting as prebiotics. Aim: To investigate whether a diet supplemented with plant-derived fructo-oligosaccharides (FOS) supports the efficacy of OIT in a murine cow's milk allergy model and to elucidate the potential mechanisms involved. Methods: After oral sensitization to the cow's milk protein whey, female C3H/HeOuJ mice were fed either a control diet or a diet supplemented with FOS (1% w/w) and received OIT (10 mg whey) 5 days a week for 3 weeks by gavage. Intradermal (i.d.) and intragastric (i.g.) challenges were performed to measure acute allergic symptoms and mast cell degranulation. Blood and organs were collected to measure antibody levels and T cell and dendritic cell populations. Spleen-derived T cell fractions (whole spleen-and CD25-depleted) were transferred to naive recipient mice to confirm the involvement of regulatory T cells (Tregs) in allergy protection induced by OIT + FOS. Results: OIT + FOS decreased acute allergic symptoms and mast cell degranulation upon challenge and prevented the challenge-induced increase in whey-specific IgE as observed in sensitized mice. Early induction of Tregs in the mesenteric lymph nodes (MLN) of OIT + FOS mice coincided with reduced T cell responsiveness in splenocyte cultures. CD25 depletion in OIT + FOS-derived splenocyte suspensions prior to transfer abolished protection against signs of anaphylaxis in recipients. OIT + FOS increased serum galectin-9 levels. No differences in short-chain fatty acid (SCFA) levels in the cecum were observed between the treatment groups. Concisely, FOS supplementation significantly improved OIT in the acute allergic skin response, %Foxp3+ Tregs and %LAP+ Th3 cells in MLN, and serum galectin-9 levels. Conclusion: FOS supplementation improved the efficacy of OIT in cow's milk allergic mice. Increased levels of Tregs in the MLN and abolished protection against signs of anaphylaxis upon transfer of CD25-depleted cell fractions, suggest a role for Foxp3+ Tregs in the protective effect of OIT + FOS. "

Water reuse and sustainable urban drainage systems

Antibiotics are a factor in developing antibiotic resistance in the environment. Outbreaks due to pathogens and resistant bacteria are an emerging issue in this decade. Resistance of Escherichia coli to two groups of antibiotics has been revised recently by the World Health Organization (WHO). These data showed that bacteria have already developed resistance to third and fourth group of antibiotics. The WHO report on surveillance and antibiotics consumption evaluation showed that antibiotic consumption varies in EU countries. Outbreaks have increased in parallel to these data depending on country, season, sex, and age group. This chapter revises the routes of spreading and surveillance of E. coli. There is a particular focus on water sources including hospitals, urban wastewater treatment plants (UWTPs), diffuse sources, and water reuse. Extensively revised data are given on the control techniques by biological and advanced processes. The emerging issue of gene transfer control in parallel to the control of bacteria is expressed. A detailed literature survey of emerging technologies of photocatalysis and nanoparticles is given.

Criminalization of market actor behavior as regulatory tool

Het onderzoek dat ten grondslag ligt aan dit artikel onderzoekt hoe de overheid markten reguleert voor (financiële) producten en diensten teneinde falen van de markt te voorkomen. Het behandelt specifiek EU Richtlijn 2014/57/EU betreffende strafrechtelijke sancties voor marktmisbruik en de implementatie daarvan in Nederland en opvolgend gebruik door het Openbaar Ministerie en Autoriteit Financiële Markten en hun Convenant ter voorkoming van ongeoorloofde samenloop van bestuurlijke en strafrechtelijke sancties. Het beantwoord de vraag of deze richtlijn de ontwikkeling van effectief reguleren van de financiële markt bevordert of remt. De slotsom ten aanzien van de implementatie van Richtlijn 2014/57/EU is – kort gezegd – dat “slechts” het aantal jaren gevangenisstraf voor handel met voorkennis en marktmisbruik van twee naar vier aangepast dient te worden. Het artikel concludeert tenslotte dat de huidige praktijk van het Convenant tussen OM en Autoriteit Financiële Markten kan blijven bestaan. De Autoriteit Financiële Markten kan haar inspanningen om haar toezicht verder in de geest van responsive regulation te verbeteren ongestoord door het OM voortzetten.

Is government a right supervisor of the regulatory enforcement?

ABSTRACT. It is now generally accepted that the quality of the regulatory arrangements should be appraised not only by looking at the institutional design, but also by evaluating the factual enforcement and implementation of regulations. It is therefore advised that national governments take a more active stance in supervising the regulatory enforcement by different regulatory agencies. However, in some cases, government’s activism might be an impeding factor in regulatory enforcement. That this is not so crazy idea shows the analysis of the regulatory enforcement by Lithuanian Competition Authority in the area of competition policy during the years of integration to the European Union. For example, not only political and financial independence of the Competition Authority was difficult to establish, but also functions and competences of the regulatory agency were changed a number of times, which hampered the effectiveness of the agency’s performance while enforcing the competition law. In addition to often changes of functions, also the scope of competences was changing. As a result, the variety of tasks attributed to the Lithuanian Competition Authority caused the growing overload of work, which further hindered its regulatory practice. The question is who can be blamed for that? Was it just the inexperience of the government who was seeking for the best institutional design and could not stop with redesigning the regulatory agency or was it the intentional behaviour guided by some concrete interests as a result of a regulatory capture? The analysis of the regulatory enforcement during the period of 15 years does not allow for disregarding of the second possibility.