Postprandial high glucose and insulin responses after starchy food consumption, associated with an increased risk of developing several metabolic diseases, could possibly be improved by altering food structure. We investigated the influence of a compact food structure; different wheat products with a similar composition were created using different processing conditions. The postprandial glucose kinetics and metabolic response to bread with a compact structure (flat bread, FB) was compared to bread with a porous structure (control bread, CB) in a randomized, crossover study with ten healthy male volunteers. Pasta (PA), with a very compact structure, was used as the control. The rate of appearance of exogenous glucose (RaE), endogenous glucose production, and glucose clearance rate (GCR) was calculated using stable isotopes. Furthermore, postprandial plasma concentrations of glucose, insulin, several intestinal hormones and bile acids were analyzed. The structure of FB was considerably more compact compared to CB, as confirmed by microscopy, XRT analysis (porosity) and density measurements. Consumption of FB resulted in lower peak glucose, insulin and glucose-dependent insulinotropic polypeptide (ns) responses and a slower initial RaE compared to CB. These variables were similar to the PA response, except for RaE which remained slower over a longer period after PA consumption. Interestingly, the GCR after FB was higher than expected based on the insulin response, indicating increased insulin sensitivity or insulin-independent glucose disposal. These results demonstrate that the structure of wheat bread can influence the postprandial metabolic response, with a more compact structure being more beneficial for health. Bread-making technology should be further explored to create healthier products.
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The focus of my research is how Bartholomeus Guesthouse (BG), founded in 1407 by Willem van Abcoude, has organized care over more than 600 years for the elderly and elderly sick people in the Centre of Utrecht. After the reorganization of 1817 -by Royal Law- the 7 (9) Guesthouses were merged to one Board called “College van Regenten der Vereenigde Gods-en Gasthuizen” .They have had their domicile in Bartholomeus Guesthouse. This Guesthouse survived as elderly care centre on particular foundation, which has meant until today that people from different religions were welcome. The properties of the other guesthouses came under supervision of the Board of “Vereenigde Gods-en Gasthuizen”. The heritage of the other foundations was , in terms of property and land, considerable. In my paper I will present the following items: -An inventarisation of the situation after 1817 and the ‘cameren’ (vrij woningen) of the different guesthouses in Utrecht and what their (living) conditions were at that time; -the Policy of the Board supervising the Free Houses/ Cameren for Elderly during this area; the observation of the archive manager S.Muller Fz.is good illustration of the situation in 1900; -the inhabitants of the ‘vrij woningen’; the selection and the rules as part of the social housing policy; - a more general analysis: the policy of poor relief and the debate of who had to take care of the poor? - all subjects give an answer to the question whether or not poor relief can be regarded as a safety valve for the (lower) middle class, in the ninetheenth century.
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Meertalige maatschappij vraagt om onderwijs gericht op meer brontalen en doeltalen (ook minderheidstalen en immigrantentalen). Leeropbrengsten in meer talen in systeem ter vergelijking van bijvoorbeeld Fries-Nederlands-Engels. Bekwaamheid leraren betreft eigen taalvaardigheid en reflectie, toepassing differentiatie en transfer. In opleidingen extra aandacht in minor tweetaligheid en master multilingualism
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