Data-driven condition-based maintenance (CBM) and predictive maintenance (PdM) strategies have emerged over recent years and aim at minimizing the aviation maintenance costs and environmental impact by the diagnosis and prognosis of aircraft systems. As the use of data and relevant algorithms is essential to AI-based gas turbine diagnostics, there are different technical, operational, and regulatory challenges that need to be tackled in order for the aeronautical industry to be able to exploit their full potential. In this work, the machine learning (ML) method of the generalised additive model (GAM) is used in order to predict the evolution of an aero engine’s exhaust gas temperature (EGT). Three different continuous synthetic data sets developed by NASA are employed, known as New Commercial Modular Aero-Propulsion System Simulation (N-CMAPSS), with increasing complexity in engine deterioration. The results show that the GAM can be predict the evolution of the EGT with high accuracy when using several input features that resemble the types of physical sensors installed in aero gas turbines currently in operation. As the GAM offers good interpretability, this case study is used to discuss the different data attributes a data set needs to have in order to build trust and move towards certifiable models in the future.