In this chapter we elaborate a hermeneutical perspective on professionalism and professional development in the wide range of professions and vocational trainings, which fall under the concern of a University of Applied Sciences (UAS). In a joint research programme of the HU UAS and Utrecht University we aim to unveil and make visible that professionals are continuously making interpretations simply by doing their jobs. Unavoidably, with these interpretations, subjectivity and normativity comes along, setting a moral agenda in the respective professional fields. We show how the more conceptual and philosophical reflections in the humanities at the Academia, is brought in interaction with professional development, vocational education and practice-oriented research at UAS. After this we walk through a number of recently completed or still ongoing research projects in the wide range of professionals in religious education (RE) via general and vocational education to non-educational professions. We end up with six developments or ‘movements’ that are taking place and that can be useful for a better understanding of complexity in vocational education and professions as such, and the imperative for change that is given by this.