Het platform voor open praktijkgericht onderzoek

Producten 11

product

Onderzoek dat ertoe doet!

Boven titel staat vermeld: De symbiose van biologie en technologie. Zowel vanuit het Applied Science onderwijs als vanuit het werkveld kwam er meer vraag om biologische expertise toe te voegen aan het bestaande lectoraat Thin Films & Functional Materials.

PDF

product

Micro-organismen als regisseurs van de duurzame eiwittransitie

In een tijd waarin de wereld geconfronteerd wordt met een toenemende bevolking en de daaruit voortvloeiende behoefte aan voedsel, staat het lectoraat Eiwittransitie voor een uiterst relevante uitdaging. De groeiende vraag naar eiwitten en de noodzaak om onze consumptiegewoonten in balans te krijgen met natuur en onze gezondheid vormen de kern van de missie van dit lectoraat.

MULTIFILE

Micro-organismen als regisseurs van de duurzame eiwittransitie

product

Emissiefactoren voor vakanties. Update voor accommodaties, activiteiten, vaartuigen en vakantietypes www⁠.klimaatwijsopreis.nl. Actualisatie mei 2024.

PDF

product

Power to methane.

Wind and solar power generation will continue to grow in the energy supply of the future, but its inherent variability (intermittency) requires appropriate energy systems for storing and using power. Storage of possibly temporary excess of power as methane from hydrogen gas and carbon dioxide is a promising option. With electrolysis hydrogen gas can be generated from (renewable) power. The combination of such hydrogen with carbon dioxide results in the energy carrier methane that can be handled well and may may serve as carbon feedstock of the future. Biogas from biomass delivers both methane and carbon dioxide. Anaerobic microorganisms can make additional methane from hydrogen and carbon dioxide in a biomethanation process that compares favourably with its chemical counterpart. Biomethanation for renewable power storage and use makes appropriate use of the existing infrastructure and knowledge base for natural gas. Addition of hydrogen to a dedicated biogas reactor after fermentation optimizes the biomethanation conditions and gives maximum flexibility. The low water solubility of hydrogen gas limits the methane production rate. The use of hollow fibers, nano-bubbles or better-tailored methane-forming microorganisms may overcome this bottleneck. Analyses of patent applications on biomethanation suggest a lot of freedom to operate. Assessment of biomethanation for economic feasibility and environmental value is extremely challenging and will require future data and experiences. Currently biomethanation is not yet economically feasible, but this may be different in the energy systems of the near future.

PDF

product

Increasing the pandemic resilience of healthcare facilities through efficient ventilation, a review of 60 healthcare buildings in the Netherlands

Clima2025 paper

MULTIFILE

Increasing the pandemic resilience of healthcare facilities through efficient ventilation, a review of 60 healthcare buildings in the Netherlands

product

Polyhydroxyalkanoate (PHA) production by thermophilic Caldimonas thermodepolymerans comb. nov. from xylan

For the future circular economy, renewable carbon feedstocks manifest considerable promise for synthesizing sustainable and biodegradable polyhydroxyalkanoate (PHA). In this study, 16 wt% and 30 wt% PHA (cell dry weight) are respectively produced by thermophilic Caldimonas thermodepolymerans from beechwood xylan and wheat arabinoxylan as the sole carbon source. Moreover, an in silico study of the potential xylan-degrading proteins was conducted using proteome sequencing and CAZyme specialized bioinformatic tools. This study demonstrates the feasibility of utilizing complex polysaccharide substrates for PHA biosynthesis, thereby potentially eliminate additional processing steps and reducing overall production costs for sustainable plastic.

MULTIFILE

product

Over energietransitie en zoveel meer

Lectorale redeboekje van dr. Klaas Jan Noorman naar aanleiding van zijn intrede in het lectoraat Energietransitie.

PDF

product

Alternative primer sets for PCR detection of genotypes involved in bacterial aerobic BTEX degradation

Eight new primer sets were designed for PCR detection of (i) mono-oxygenase and dioxygenase gene sequences involved in initial attack of bacterial aerobic BTEX degradation and of (ii) catechol 2,3-dioxygenase gene sequences responsible for meta-cleavage of the aromatic ring. The new primer sets allowed detection of the corresponding genotypes in soil with a detection limit of 10(3)-10(4) or 10(5)-10(6) gene copies g(-1) soil, assuming one copy of the gene per cell. The primer sets were used in PCR to assess the distribution of the catabolic genes in BTEX degrading bacterial strains and DNA extracts isolated from soils sampled from different locations and depths (vadose, capillary fringe and saturated zone) within a BTEX contaminated site. In both soil DNA and the isolates, tmoA-, xylM- and xylE1-like genes were the most frequently recovered BTEX catabolic genes. xylM and xylE1 were only recovered from material from the contaminated samples while tmoA was detected in material from both the contaminated and non-contaminated samples. The isolates, mainly obtained from the contaminated locations, belonged to the Actinobacteria or Proteobacteria (mainly Pseudomonas). The ability to degrade benzene was the most common BTEX degradation phenotype among them and its distribution was largely congruent with the distribution of the tmoA-like genotype. The presence of tmoA and xylM genes in phylogenetically distant strains indicated the occurrence of horizontal transfer of BTEX catabolic genes in the aquifer. Overall, these results show spatial variation in the composition of the BTEX degradation genes and hence in the type of BTEX degradation activity and pathway, at the examined site. They indicate that bacteria carrying specific pathways and primarily carrying tmoA/xylM/xylE1 genotypes, are being selected upon BTEX contamination.

PDF

product

Indole-3-carbinol, a plant nutrient and AhR-Ligand precursor, supports oral tolerance against OVA and improves peanut allergy symptoms in mice

From PLoS website: In general, dietary antigens are tolerated by the gut associated immune system. Impairment of this so-called oral tolerance is a serious health risk. We have previously shown that activation of the ligand-dependent transcription factor aryl hydrocarbon receptor (AhR) by the environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) affects both oral tolerance and food allergy. In this study, we determine whether a common plant-derived, dietary AhR-ligand modulates oral tolerance as well. We therefore fed mice with indole-3-carbinole (I3C), an AhR ligand that is abundant in cruciferous plants. We show that several I3C metabolites were detectable in the serum after feeding, including the high-affinity ligand 3,3´-diindolylmethane (DIM). I3C feeding robustly induced the AhR-target gene CYP4501A1 in the intestine; I3C feeding also induced the aldh1 gene, whose product catalyzes the formation of retinoic acid (RA), an inducer of regulatory T cells. We then measured parameters indicating oral tolerance and severity of peanut-induced food allergy. In contrast to the tolerance-breaking effect of TCDD, feeding mice with chow containing 2 g/kg I3C lowered the serum anti-ovalbumin IgG1 response in an experimental oral tolerance protocol. Moreover, I3C feeding attenuated symptoms of peanut allergy. In conclusion, the dietary compound I3C can positively influence a vital immune function of the gut.

MULTIFILE

Producten 11

product

Onderzoek dat ertoe doet!

PDF

product

Micro-organismen als regisseurs van de duurzame eiwittransitie

MULTIFILE

product

Emissiefactoren voor vakanties. Update voor accommodaties, activiteiten, vaartuigen en vakantietypes www⁠.klimaatwijsopreis.nl. Actualisatie mei 2024.

PDF

product

Power to methane.

PDF

product

Increasing the pandemic resilience of healthcare facilities through efficient ventilation, a review of 60 healthcare buildings in the Netherlands

Clima2025 paper

MULTIFILE

product

Polyhydroxyalkanoate (PHA) production by thermophilic Caldimonas thermodepolymerans comb. nov. from xylan

MULTIFILE

product

Over energietransitie en zoveel meer

Lectorale redeboekje van dr. Klaas Jan Noorman naar aanleiding van zijn intrede in het lectoraat Energietransitie.

PDF

product

Alternative primer sets for PCR detection of genotypes involved in bacterial aerobic BTEX degradation

PDF

product

Indole-3-carbinol, a plant nutrient and AhR-Ligand precursor, supports oral tolerance against OVA and improves peanut allergy symptoms in mice

MULTIFILE

Zoekresultaten

Producten 11

Onderzoek dat ertoe doet!

Micro-organismen als regisseurs van de duurzame eiwittransitie

Emissiefactoren voor vakanties. Update voor accommodaties, activiteiten, vaartuigen en vakantietypes www⁠.klimaatwijsopreis.nl. Actualisatie mei 2024.

Power to methane.

Increasing the pandemic resilience of healthcare facilities through efficient ventilation, a review of 60 healthcare buildings in the Netherlands

Polyhydroxyalkanoate (PHA) production by thermophilic Caldimonas thermodepolymerans comb. nov. from xylan

Over energietransitie en zoveel meer

Alternative primer sets for PCR detection of genotypes involved in bacterial aerobic BTEX degradation

Indole-3-carbinol, a plant nutrient and AhR-Ligand precursor, supports oral tolerance against OVA and improves peanut allergy symptoms in mice

Navigeer naar

Categorieën

Filters

Producten 11

Onderzoek dat ertoe doet!

Micro-organismen als regisseurs van de duurzame eiwittransitie

Emissiefactoren voor vakanties. Update voor accommodaties, activiteiten, vaartuigen en vakantietypes www⁠.klimaatwijsopreis.nl. Actualisatie mei 2024.

Power to methane.

Increasing the pandemic resilience of healthcare facilities through efficient ventilation, a review of 60 healthcare buildings in the Netherlands

Polyhydroxyalkanoate (PHA) production by thermophilic Caldimonas thermodepolymerans comb. nov. from xylan

Over energietransitie en zoveel meer

Alternative primer sets for PCR detection of genotypes involved in bacterial aerobic BTEX degradation

Indole-3-carbinol, a plant nutrient and AhR-Ligand precursor, supports oral tolerance against OVA and improves peanut allergy symptoms in mice