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Wat te doen als je ouderenmishandeling vermoedt?

Ouderenmishandeling is een belangrijk maatschappelijk probleem. Het hangt samen met verschillende negatieve gezondheidsuitkomsten, waaronder verhoogde mortaliteit en morbiditeit, psychologische stress en een groter gebruik van de gezondheidszorg. 1 Toch signaleren zorgprofessionals het nog onvoldoende en is er sprake van een hoge mate van handelingsverlegenheid. Dit mede door onbekendheid met het probleem en kennistekort. Daarnaast rust er zowel onder patiënten als onder zorgprofessionals nog steeds een groot taboe op het bespreekbaar maken van dit onderwerp. 2-4 Ouderenmishandeling komt in allerlei vormen voor en betreft ‘al het handelen of het nalaten van handelen

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Wat te doen als je ouderenmishandeling vermoedt?
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International multi-stakeholder consensus statement on clinical trial integrity

Objective: To prepare a set of statements for randomised clinical trials (RCT) integrity through an international multi-stakeholder consensus. Methods: The consensus was developed via: multi-country multidisciplinary stakeholder group composition and engagement; evidence synthesis of 55 systematic reviews concerning RCT integrity; anonymised two-round modified Delphi survey with consensus threshold based on the average percentage of majority opinions; and, a final consensus development meeting. Prospective registrations: (https://osf.io/bhncy, https://osf.io/3ursn). Results: There were 30 stakeholders representing 15 countries from five continents including triallists, ethicists, methodologists, statisticians, consumer representatives, industry representatives, systematic reviewers, funding body panel members, regulatory experts, authors, journal editors, peer-reviewers and advisors for resolving integrity concerns. Delphi survey response rate was 86.7% (26/30 stakeholders). There were 111 statements (73 stakeholder-provided, 46 systematic review-generated, 8 supported by both) in the initial long list, with eight additional statements provided during the consensus rounds. Through consensus the final set consolidated 81 statements (49 stakeholder-provided, 41 systematic review-generated, 9 supported by both). The entire RCT life cycle was covered by the set of statements including general aspects (n = 6), design and approval (n = 11), conduct and monitoring (n = 19), reporting of protocols and findings (n = 20), post-publication concerns (n = 12), and future research and development (n = 13). Conclusion: Implementation of this multi-stakeholder consensus statement is expected to enhance RCT integrity.

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International multi-stakeholder consensus statement on clinical trial integrity
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Long lockdowns and rainy days: Modeling the interactive roles of weather, behavior, and restrictions in COVID-19 transmission in the Netherlands

Extant research on the role of weather in COVID-19 has produced ambiguous results and much methodological debate. Following advice emerging from this methodological debate, we take a step further in modeling effects of weather on COVID-19 spread by including interactions between weather, behavior, baseline cases, and restrictions in our model. Our model was based on secondary infection, hospitalization, restriction, weather, and mobility data per day nested with safety region in the Netherlands. Our findings show significant but inconsistent interactions. The robust effects of weather on COVID-19 spread persisted over and above these interactions, highlighting the need to account for weather with nuance and caution in public policy, communication, and forecasting

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