Although there is some evidence that total dietary antioxidant capacity (TDAC) is inversely associated with the presence of obesity, no longitudinal studies have been performed investigating the effect of TDAC on comprehensive measures of body composition over time. In this study, we included 4595 middle-aged and elderly participants from the Rotterdam Study, a population-based cohort. We estimated TDAC among these individuals by calculating a ferric reducing ability of plasma (FRAP) score based on data from food-frequency questionnaires. Body composition was assessed by means of dual X-ray absorptiometry at baseline and every subsequent 3-5 years. From these data, we calculated fat mass index (FMI), fat-free mass index (FFMI), android-to-gynoid fat ratio (AGR), body fat percentage (BF%) and body mass index (BMI). We also assessed hand grip strength at two time points and prevalence of sarcopenia at one time point in a subset of participants. Data were analyzed using linear mixed models or multinomial logistic regression models with multivariable adjustment. We found that higher FRAP score was associated with higher FFMI (0.091 kg/m2 per standard deviation (SD) higher FRAP score, 95% CI 0.031; 0.150), lower AGR (-0.028, 95% CI -0.053; -0.003), higher BMI (0.115, 95% CI 0.020; 0.209) and lower BF% (-0.223, 95% CI -0.383; -0.064) across follow-up after multivariable adjustment. FRAP score was not associated with hand grip strength or sarcopenia. Additional adjustment for adherence to dietary guidelines and exclusion of individuals with comorbid disease at baseline did not change our results. In conclusion, dietary intake of antioxidants may positively affect the amount of lean mass and overall body composition among the middle-aged and elderly.
Aim of the researchAim of this study is to understand which approach (expert or process orientated) sport club consultants use in succesfully raising the organizational capacity of voluntary sport clubs in the northern part of the Netherlands. Around 130 professional sport club consultants are active in the northern part of the Netherlands, but it is not clear which approach they use in raising the organizational capacity of the clubs within a specific context and if this approach is effective. Theoretical backgroundA sport club with great organizational capacity has the ability to offer their sport, now and in the future, in a sustainable and socially responsible way to (potential) members. Dutch voluntary sport clubs (VSCs) are facing several challenges in perceived consumerist behavior by members (Van der Roest, 2015), demands by the government to attribute to the social policy agenda (Coalter, 2007) and declining number of members in complex contexts (Wollebæk, 2009). Between 300-500 sport club consultants, mostly funded by local governments or sport associations, are tasked to raise the organizational capacity of these VSCs in the Netherlands Most consultants play an expert role delivering generic interventions on specific topics as recruiting volunteers, sponsorships or positive behavior support. The other consultants play a process consultation role in which a holistic strategic change approach is used for more sustainable organizational development (Schein, 1999). The context of the organizations (VSC’s) is determining which approach is the best in developing the organizational capacity. But most of the time consultants use the same, mostly expert role, in consulting the organizations (Boonstra & Elving, 2009). Therefore it is not clear which approach (expert or process orientated) sport club consultants in the Netherlands use in raising the organizational capacity of VSC’s in different contexts. Methodology, research design, and data analysisThe study will be conducted from March 2017 till the end of July 2017 in the northern part of the Netherlands. In March we have started .with identifying successful sport club consultants in three steps: these steps show a qualitative description of the current competences, approaches and interventions (repertoire) as seen by the sport club consultants in our target group:1) A group of experts have been gathered to formulate criteria for the competences, approaches and interventions of a successful process orientated sport club consultant. 2) The criteria from step 1 are validated by theory about organizational development and consulting of organizations. Thereafter the criteria are processed into a digital survey 3) The survey has been send to n=130 sport club consultants in the northern part of the Netherlands. 4) Based on the output of the survey, profiles will be developed of different types sport club consultants (process orientated, mediator, supporter, coach, expert) and the approaches per type of consultant. For each profile a ranking will be made based on which criteria (from step 1) the consultants meet. This ranking will be used to make a selection of successful sport club consultants to conduct research in five multiple case studies. From June on multiple case studies will be conducted in which five process consultants are working with a VSC. A case study protocol will be developed that observe the consultant in three sessions at the club In addition interviews will be conducted with the consultant, the board of the club, and other relevant stakeholders. With a cross-case synthesis patterns will be developed in the way the consultants worked and how these approaches were interpreted and valued by the various stakeholders. Results, discussion, and implications/conclusionsIn the expected results both approaches and interventions (repertoire) of the consultant as their competences and qualities are analyzed which will result in the profiling of the active sport club consultants. We also gain insights in which approach of the sport club consultants is the most effective in raising the organizational capacity of a VSC in a given context. New insights on how consultants can successfully contribute to the sustainable organizational development of VSCs will be presented.
From the article: Many organizations are striving for a structural and professional approach toward business information management (BIM). With help of BiSL they can shape the BIM responsibilities and processes, but they struggle with the required capacity for the BIM activities necessary for their particular situation. Therefore, research was started to develop an instrument to determine the required capacity of the BIM activities in an organization. In this paper the construction of the instrument will be described. A limited set of factors may be of importance to identify the required capacity of BIM activities that is needed: complexity of business processes, complexity of IS/IT, dynamics of the organization and its environment and the size of the organization are examples of relevant factors. However, factors that appear relevant may prove useless in practice due to the fact that organizations have no data on these indicators available. Furthermore, the relationships between the present and desired quality of information and information services are part of the instrument. The instrument was tested in practice to determine the usefulness. The results show that the instrument has the potential to determine the required capacity of BIM.
MULTIFILE
The anterior cruciate ligament (ACL) is a strong rope-like tissue which connects the femur to the tibia in the knee joint. Its function is to provide structural stability to the knee while preventing unnatural forward movement of the tibia relative to the femur. Acute complete ACL ruptures during movements like knee hyperextension or sudden changes of direction (pivoting) damage two entities: the ligament itself and its nerve connections to the posterior tibial nerve (PTN). PTN innervation in the ACL is essential for: a) proprioception (e.g. perception of position and movement/acceleration experienced by the ligament), and b) stability of the knee joint. Upon ACL rupture, the orthopedic surgeon reconstructs the ACL with a graft from the hamstring, patellar or quadriceps tendon. After the surgery, the goal is to regain neuromuscular control and dynamic stabilization during rehabilitation as soon as possible for a quick return to sports and daily activities. However, surgeons are not able to reconstruct the nerve gap between the PTN and the grafted ligament due to the microscopic size of the innervation in the ACL. Not linking the PTN to the graft creates a disconnection between the knee joint and the spinal cord. To mitigate these disadvantages in ACL surgery, this study focuses on activating the growth of proprioception nerve endings using a ligament loaded with growth factors (neurotrophins). We hypothesize that neurotrophins will activate proprioceptive fibers of neurons close to the ACL. We describe graft fabrication steps and in vitro experiments to expand on the regeneration capacity of a commercially available ACL-like synthetic ligament called LARS. The results will bring the ACL regeneration field closer to having a graft that can aid patients in regaining mobility and stability during locomotion and running, confidence in the strength of the knee joint, and quick return to sports.
The maximum capacity of the road infrastructure is being reached due to the number of vehicles that are being introduced on Dutch roads each day. One of the plausible solutions to tackle congestion could be efficient and effective use of road infrastructure using modern technologies such as cooperative mobility. Cooperative mobility relies majorly on big data that is generated potentially by millions of vehicles that are travelling on the road. But how can this data be generated? Modern vehicles already contain a host of sensors that are required for its operation. This data is typically circulated within an automobile via the CAN bus and can in-principle be shared with the outside world considering the privacy aspects of data sharing. The main problem is, however, the difficulty in interpreting this data. This is mainly because the configuration of this data varies between manufacturers and vehicle models and have not been standardized by the manufacturers. Signals from the CAN bus could be manually reverse engineered, but this process is extremely labour-intensive and time-consuming. In this project we investigate if an intelligent tool or specific test procedures could be developed to extract CAN messages and their composition efficiently irrespective of vehicle brand and type. This would lay the foundations that are required to generate big data-sets from in-vehicle data efficiently.
This project develops a European network for transdisciplinary innovation in artistic engagement as a catalyst for societal transformation, focusing on immersive art. It responds to the professionals in the field’s call for research into immersive art’s unique capacity to ‘move’ people through its multisensory, technosocial qualities towards collective change. The project brings together experts leading state-of-the-art research and practice in related fields with an aim to develop trajectories for artistic, methodological, and conceptual innovation for societal transformation. The nascent field of immersive art, including its potential impact on society, has been identified as a priority research area on all local-to-EU levels, but often suffers from the common (mis)perception as being technological spectacle prioritising entertainment values. Many practitioners create immersive art to enable novel forms of creative engagement to address societal issues and enact change, but have difficulty gaining recognition and support for this endeavour. A critical challenge is the lack of knowledge about how their predominantly sensuous and aesthetic experience actually lead to collective change, which remains unrecognised in the current systems of impact evaluation predicated on quantitative analysis. Recent psychological insights on awe as a profoundly transformative emotion signals a possibility to address this challenge, offering a new way to make sense of the transformational effect of directly interacting with such affective qualities of immersive art. In parallel, there is a renewed interest in the practice of cultural mediation, which brings together different stakeholders to facilitate negotiation towards collective change in diverse domains of civic life, often through creative engagements. Our project forms strategic grounds for transdisciplinary research at the intersection between these two developments. We bring together experts in immersive art, psychology, cultural mediation, digital humanities, and design across Europe to explore: How can awe-experiences be enacted in immersive art and be extended towards societal transformation?