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Factsheet Bezorgeconomie : de effecten op mobiliteit, milieu en leefomgeving

Factsheet Parlement en Wetenschap: Deze factsheet is tot stand gekomen in het kader van de samenwerking tussen de Tweede Kamer, de KNAW, NWO, VSNU en de jonge Akademie

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A randomized study of the effect of carbonated water prior to myocardial SPECT

Objective: In myocardial perfusion single-photon emission computed tomography (SPECT), abdominal activity often interferes with the evaluation of perfusion in the inferior wall, especially after pharmacological stress. In this randomized study, we examined the effect of carbonated water intake versus still water intake on the quality of images obtained during myocardial perfusion images (MPI) studies. Methods: A total of 467 MIBI studies were randomized into a carbonated water group and a water group. The presence of intestinal activity adjacent to the inferior wall was evaluated by two observers. Furthermore, a semiquantitative analysis was performed in the adenosine subgroup,using a count ratio of the inferior myocardial wall and adjacent abdominal activity. Results: The need for repeated SPECT in the adenosine studies was 5.3 % in the carbonated water group versus 19.4 % in the still water group (p = 0.019). The inferior wall-to-abdomen count ratio was significantly higher in the carbonated water group compared to the still water group (2.11 ± 1.00 vs. 1.72 ± 0.73, p\0.001). The effect of carbonated water during rest and after exercise was not significant. Conclusions: This randomized study showed that carbonated water significantly reduced the interference of extra-cardiac activity in adenosine SPECT MPI. Keywords: Extra-cardiac radioactivity, Myocardial SPECT, Image quality enhancement, Carbonated water

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A randomized study of the effect of carbonated water prior to myocardial SPECT

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Thermoharders: kort & bondig

Het boekje ‘Thermoharders: kort & bondig’ van het Saxion Kenniscentrum Design en Technologie beschrijft de onderzoeksresultaten van het project Materialen in Ontwerp 1, deelproject Thermoharder. Het boekje is geschreven om meer informatie te geven over thermoharders. Het produceren van thermoharder producten is een arbeidsintensief proces. Daarom wordt het steeds lastiger om te kunnen concurreren met thermoplasten. De thermoharderindustrie richt zich steeds meer op niche markten. Hier kunnen de specifieke eigenschappen van thermoharders goed benut worden. Helaas is kennis over thermoharders geen algemeen goed meer. Vaak weet men te vertellen dat de thermoharders over het algemeen beter tegen hitte kunnen dan thermoplasten, maar daar houdt het vaak op. Door het gebrek aan kennis over thermoharders wordt het materiaal vaak niet als productmateriaal in overwegingen meegenomen, terwijl het materiaal uitstekend aansluit bij sommige specificaties van nichemarktproducten. Om deze kans te benutten, geeft dit boekje een uiteenzetting van typische materiaaleigenschappen, thermoharders in composieten, verschillende productietechnieken en verschillende toepassingen.

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Polyhydroxyalkanoate (PHA) production by thermophilic Caldimonas thermodepolymerans comb. nov. from xylan

For the future circular economy, renewable carbon feedstocks manifest considerable promise for synthesizing sustainable and biodegradable polyhydroxyalkanoate (PHA). In this study, 16 wt% and 30 wt% PHA (cell dry weight) are respectively produced by thermophilic Caldimonas thermodepolymerans from beechwood xylan and wheat arabinoxylan as the sole carbon source. Moreover, an in silico study of the potential xylan-degrading proteins was conducted using proteome sequencing and CAZyme specialized bioinformatic tools. This study demonstrates the feasibility of utilizing complex polysaccharide substrates for PHA biosynthesis, thereby potentially eliminate additional processing steps and reducing overall production costs for sustainable plastic.

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Numerical Simulation as a Precedence Method

CC-BYNatural ventilation has been used widely in buildings to deliver a healthy and comfortable indoor environment for occupants. It also reduces the consumption of energy in the built environment and dilutes the concentration of carbon dioxide. Various methods and techniques have been used to evaluate and predict indoor airspeed and patterns in buildings. However, few studies have been implemented to investigate the relevant methods and tools for the evaluation of ventilation performance in indoor and outdoor spaces. The current study aims to review available methods, identifying reliable ones to apply in future research. This study investigates scientific databases and compares the advantages and drawbacks of methods including analytical models, empirical models, zonal models, and CFD models. wind-driven ventilation; analytical models; experimental models; zonal models; computational fluid dynamics (CFD) models; numerical discretization methods https://www.mdpi.com/2071-1050/13/22/12721Sustainability 2021, 13(22), 12721

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Comparing the Effectiveness of the Blended Delivery Mode With the Face-to-Face Delivery Mode of Smoking Cessation Treatment

Background:Tobacco consumption is a leading cause of death and disease, killing >8 million people each year. Smoking cessation significantly reduces the risk of developing smoking-related diseases. Although combined treatment for addiction is promising, evidence of its effectiveness is still emerging. Currently, there is no published research comparing the effectiveness of blended smoking cessation treatments (BSCTs) with face-to-face (F2F) treatments, where web-based components replace 50% of the F2F components in blended treatment.Objective:The primary objective of this 2-arm noninferiority randomized controlled trial was to determine whether a BSCT is noninferior to an F2F treatment with identical ingredients in achieving abstinence rates.Methods:This study included 344 individuals who smoke (at least 1 cigarette per day) attending an outpatient smoking cessation clinic in the Netherlands. The participants received either a blended 50% F2F and 50% web-based BSCT or only F2F treatment with similar content and intensity. The primary outcome measure was cotinine-validated abstinence rates from all smoking products at 3 and 15 months after treatment initiation. Additional measures included carbon monoxide–validated point prevalence abstinence; self-reported point prevalence abstinence; and self-reported continuous abstinence rates at 3, 6, 9, and 15 months after treatment initiation.Results:None of the 13 outcomes showed statistically confirmed noninferiority of the BSCT, whereas 4 outcomes showed significantly (P<.001) inferior abstinence rates of the BSCT: cotinine-validated point prevalence abstinence rate at 3 months (difference 12.7, 95% CI 6.2-19.4), self-reported point prevalence abstinence rate at 6 months (difference 19.3, 95% CI 11.5-27.0) and at 15 months (difference 11.7, 95% CI 5.8-17.9), and self-reported continuous abstinence rate at 6 months (difference 13.8, 95% CI 6.8-20.8). The remaining 9 outcomes, including the cotinine-validated point prevalence abstinence rate at 15 months, were inconclusive.Conclusions:In this high-intensity outpatient smoking cessation trial, the blended mode was predominantly less effective than the traditional F2F mode. The results contradict the widely assumed potential benefits of blended treatment and suggest that further research is needed to identify the critical factors in the design of blended interventions.Trial Registration:Netherlands Trial Register 27150; https://onderzoekmetmensen.nl/nl/trial/27150

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Comparing the Effectiveness of the Blended Delivery Mode With the Face-to-Face Delivery Mode of Smoking Cessation Treatment

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Differences in acetate recovery factor between groups may interfere with tracer estimates of fat oxidation (letter to the editor)

This letter to the editor argues that the assumption of a single value for the acetate recovery factor in carbon-13 stable isotope research for different individuals, can lead to significant errors in the outcomes of substrate utilization measurements.

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Differences in acetate recovery factor between groups may interfere with tracer estimates of fat oxidation (letter to the editor)

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Implementing Product-Service System Business Models in the Building and Construction Sector

The building and construction industry, which is responsible for 39% of global carbon emissions, is far off track in achieving its net-zero emission targets. Product-service system (PSS) business models are one of the instruments used by the industry in the transition toward reaching these targets. A PSS business model is designed around an end-of-life solution that minimizes material usage and maximizes energy efficiency. It is provided to customers as a marketable set of products and services, jointly capable of fulfilling a customer’s needs. There are signals from practice however, that suggest that the implementation of this type of business model is falling behind. This study investigates this and seeks to identify key challenges and opportunities for sustainable PSS business models in the built environment. Using a grounded theory approach, data from 13 semi-structured interviews across five companies is used to identify challenges and opportunities that suppliers are facing in selling their products through PSS business models. Our preliminary data analysis points to nine challenges and opportunities for PSS business models. We discuss these in the context of the current economic transition toward a sustainable and circular built environment and provide suggestions for further research that could help to overcome resistance toward the implementation of PSS business models. The contribution of this research to researchers and practitioners is that it provides insights into the adoption of new business models in fragmented and competitive business environments.

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Reduced oxidation rates of ingested glucose during prolonged exercise with low endogenous CHO availability

This paper descibes a study that shows that glycogen-lowering exercise, performed the evening before an exercise bout in combination with glycogen restriction leads to a reduction of the oxidation rate of ingested glucose during moderate-intensity exercise

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Producten 755

Factsheet Bezorgeconomie : de effecten op mobiliteit, milieu en leefomgeving

A randomized study of the effect of carbonated water prior to myocardial SPECT

Thermoharders: kort & bondig

Polyhydroxyalkanoate (PHA) production by thermophilic Caldimonas thermodepolymerans comb. nov. from xylan

Numerical Simulation as a Precedence Method

Comparing the Effectiveness of the Blended Delivery Mode With the Face-to-Face Delivery Mode of Smoking Cessation Treatment

Differences in acetate recovery factor between groups may interfere with tracer estimates of fat oxidation (letter to the editor)

Implementing Product-Service System Business Models in the Building and Construction Sector

Reduced oxidation rates of ingested glucose during prolonged exercise with low endogenous CHO availability

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Producten 755

Factsheet Bezorgeconomie : de effecten op mobiliteit, milieu en leefomgeving

A randomized study of the effect of carbonated water prior to myocardial SPECT

Thermoharders: kort & bondig

Polyhydroxyalkanoate (PHA) production by thermophilic Caldimonas thermodepolymerans comb. nov. from xylan

Numerical Simulation as a Precedence Method

Comparing the Effectiveness of the Blended Delivery Mode With the Face-to-Face Delivery Mode of Smoking Cessation Treatment

Differences in acetate recovery factor between groups may interfere with tracer estimates of fat oxidation (letter to the editor)

Implementing Product-Service System Business Models in the Building and Construction Sector

Reduced oxidation rates of ingested glucose during prolonged exercise with low endogenous CHO availability