To understand how transition across different thermal zones in a building impacts the thermal perception of occupants, the current work examines occupant feedback in two work environments — nursing staff in hospital wards and the workers in an office. Both studies used a mix of subjective surveys and objective measurements. A total of 96 responses were collected from the hospital wards while 142 were collected from the office. The thermal environment in the hospital wards was perceived as slightly warm on the ASHRAE thermal sensation scale (mean TSV = 1.2), while the office workers rated their environment on the cool side (mean TSV = 0.15). The results also show that when the transitions were across temperature differences within 2 °C, the thermal perception was not impacted by the magnitude of the temperature difference — as reflected in occupant thermal sensation and thermal comfort/thermal acceptability vote. This would imply that the effect of temperature steps on thermal perception, if any, within these boundaries, was extremely short lived. These findings go towards establishing the feasibility of heterogeneous indoor thermal environments and thermal zoning of workspaces for human comfort.
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Activity-based work environments are widely adopted; however, research shows mixed findings regarding privacy issues, satisfaction with the work environment, and task performance. To further our understanding, two complementary studies drawing on Person-Environment fit theory were conducted: (1) A field study using experience sampling, and (2) A lab study in a virtual reality studio. The results from both studies confirm that perceived fit is a function of activity, work setting, and personal need for privacy, with indirect effects on satisfaction with the work environment (Studies 1 and 2) and task performance (Study 2). Across both studies, a misfit was perceived particularly among workers high in personal need for privacy when performing high-complexity tasks in an open office work setting. Hence, we recommend that organizations facilitate and stimulate their workers to create better fits between activities, work settings, and personal characteristics.
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This research paper looks at a selection of science-fiction films and its connection with the progression of the use of television, telephone and print media. It also analyzes statistical data obtained from a questionnaire conducted by the research group regarding the use of communication media.
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This paper explores the impact of the physical and social dimensions of the work environment on satisfaction and perceived productivity of knowledge workers in Dutch universities of applied sciences. The approach took the form of a literature review, multiple case study of six research centres using interviews and logbook analysis, and web-based survey (N = 188). Optimally facilitating knowledge production requires both space for concentration (to support internalisation of knowledge) and space for interaction (to support externalisation of knowledge). None of the work environments involved in the study adequately supported all the phases of knowledge development adequately. Cellular offices with personal desks are preferred for solo work and, whereas new workplace designs with a focus on the office as a meeting place support interaction and collaboration. Spatial layout and interaction have a stronger impact than comfort and absence of distraction. The spatial layout should support both in-depth concentration and communication, fit the internalisation/externalisation ratio of activities, and accommodate the proximity essential for collaborative knowledge development. Being able to choose is the key to success. In terms of research limitations, knowledge workers’ productivity was measured by self-assessment, but only a limited number of diaries were collected. The lessons learned can be used as inputs to decision-making processes regarding the design, implementation and management of working environments in higher education settings. Few studies have been conducted concerning the spatial preferences and needs of knowledge workers in universities of applied sciences. The results show that the physical dimension (comfort and layout) is more important for collective productivity, whereas individual productivity is more strongly influenced by the social dimension (interaction and distraction).
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This paper explores the impact of the physical and social dimensions of the work environment on satisfaction and perceived productivity of knowledge workers in Dutch universities of applied sciences. The approach took the form of a literature review, multiple case study of six research centres using interviews and logbook analysis, and web-based survey (N = 188). Optimally facilitating knowledge production requires both space for concentration (to support internalisation of knowledge) and space for interaction (to support externalisation of knowledge). None of the work environments involved in the study adequately supported all the phases of knowledge development adequately. Cellular offices with personal desks are preferred for solo work and, whereas new workplace designs with a focus on the office as a meeting place support interaction and collaboration. Spatial layout and interaction have a stronger impact than comfort and absence of distraction. The spatial layout should support both in-depth concentration and communication, fit the internalisation/externalization ratio of activities, and accommodate the proximity essential for collaborative knowledge development. Being able to choose is the key to success. In terms of research limitations, knowledge workers’ productivity was measured by self-assessment, but only a limited number of diaries were collected. The lessons learned can be used as inputs to decision-making processes regarding the design, implementation and management of workingenvironments in higher education settings. Few studies have been conducted concerning the spatial preferences and needs of knowledge workers in universities of applied sciences. The results show that the physical dimension (comfort and layout) is more important for collective productivity, whereas individual productivity is more strongly influenced by the social dimension (interaction and distraction).
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In BOP ventures the notion of “selling to the poor” has steadily been replaced by business approaches that suggest sustainable value creation. This has certain implications, in particular the development of strategies that serve triple bottom-line goals. These include economic, social and environmental benefits, in other words, the well known goals of people-planet-profit. However to optimise value-creation one ideally needs to follow a strategy that is based on some form of conceptual model that can serve as a frame of reference. This paper proposes such a conceptual model. The research was undertaken in 8 BOP projects involving multinational information and communication technology companies in Africa. ICT is relevant here because of frequently high expectations that it contributes positively to development goals. A study of the BOP literature reveals that several elements need consideration when trying to create value in developing areas. In addition it emerges that these elements are somehow interdependent. Using information found in the literature as guide a study of 8 cases was undertaken. The research approach was the case study method and the data was analysed for emerging patterns. Primary and secondary data was collected through interviews as well as a close study of archival and other sources. The analysis revealed three high level factors that may need to be aligned in order to ensure optimised value creation of BOP ventures. These three factors are BOP strategy, partnerships, and products & services development. It is also confirmed that neither BOP strategy nor partnerships nor products/service development can be synthesised independently from the rest. There is a delicate balance and interaction between the three where all three are interdependent and mutually influence each other.
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From teh UU repository: "Background: Oral immunotherapy (OIT) is a promising therapeutic approach to treat food allergic patients. However, there are some concerns regarding its safety and long-term efficacy. The use of non-digestible oligosaccharides might improve OIT efficacy since they are known to directly modulate intestinal epithelial and immune cells in addition to acting as prebiotics. Aim: To investigate whether a diet supplemented with plant-derived fructo-oligosaccharides (FOS) supports the efficacy of OIT in a murine cow's milk allergy model and to elucidate the potential mechanisms involved. Methods: After oral sensitization to the cow's milk protein whey, female C3H/HeOuJ mice were fed either a control diet or a diet supplemented with FOS (1% w/w) and received OIT (10 mg whey) 5 days a week for 3 weeks by gavage. Intradermal (i.d.) and intragastric (i.g.) challenges were performed to measure acute allergic symptoms and mast cell degranulation. Blood and organs were collected to measure antibody levels and T cell and dendritic cell populations. Spleen-derived T cell fractions (whole spleen-and CD25-depleted) were transferred to naive recipient mice to confirm the involvement of regulatory T cells (Tregs) in allergy protection induced by OIT + FOS. Results: OIT + FOS decreased acute allergic symptoms and mast cell degranulation upon challenge and prevented the challenge-induced increase in whey-specific IgE as observed in sensitized mice. Early induction of Tregs in the mesenteric lymph nodes (MLN) of OIT + FOS mice coincided with reduced T cell responsiveness in splenocyte cultures. CD25 depletion in OIT + FOS-derived splenocyte suspensions prior to transfer abolished protection against signs of anaphylaxis in recipients. OIT + FOS increased serum galectin-9 levels. No differences in short-chain fatty acid (SCFA) levels in the cecum were observed between the treatment groups. Concisely, FOS supplementation significantly improved OIT in the acute allergic skin response, %Foxp3+ Tregs and %LAP+ Th3 cells in MLN, and serum galectin-9 levels. Conclusion: FOS supplementation improved the efficacy of OIT in cow's milk allergic mice. Increased levels of Tregs in the MLN and abolished protection against signs of anaphylaxis upon transfer of CD25-depleted cell fractions, suggest a role for Foxp3+ Tregs in the protective effect of OIT + FOS. "
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Bespreking van onderzoek van Rychard Bouwens in ‘Waar wij trots op zijn. De ontdekkingen van 2011’ van de Universiteit Leiden Faculteit der Wiskunde & Natuurwetenschappen. Het valt goed te begrijpen voor iedereen met een basale kennis van klassieke fotografie: bij weinig licht neem je een lange sluitertijd. En dat is wat Rychard Bouwens deed. Om naar de zogenaamde Dark Ages van het heelal te kijken, hield hij de Hubble-ruimtetelescoop maar liefst 87 uur lang op een plek gericht.
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Bespreking van onderzoek van Todor Stefanov in ‘Waar wij trots op zijn. De ontdekkingen van 2011’ van de Universiteit Leiden Faculteit der Wiskunde & Natuurwetenschappen. De Bulgaar Todor Stefanov onderzoekt methoden en middelen voor het ontwerpen en programmeren van multiprocessorsystemen die zijn geïntegreerd in een enkele chip. Dit om de verwerking van signalen en beelden in bijvoorbeeld smartphones te verbeteren. En dat moet snel, want ieder jaar komt er wel weer een nieuwe generatie op de markt.
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Bespreking van onderzoek van Erik Danen in ‘Waar wij trots op zijn. De ontdekkingen van 2011’ van de Universiteit Leiden Faculteit der Wiskunde & Natuurwetenschappen. Celbioloog Erik Danen doet onderzoek naar de verwoestende – maar in evolutionaire termen ook wonderlijke – strategieën van de kankercel. Met welke trucs verspreiden kankercellen zich door het lichaam? Hoe overleven ze een aanval van een chemokuur? En hoe wrang is het dat de één procent cellen die de therapie overleeft vervolgens dubbelhard terugslaat.
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