In de geestelijke gezondheidszorg wordt in toenemende mate wetenschappelijk onderzoek gedaan, vooral in het kader van opleidingen. Er is onbekendheid met de regelgeving en ethiek bij beginnend onderzoekers. Zorgvuldige overwegingen - conform de richtlijnen voor good clinical practice (gcp) en medisch-ethische toetsing, worden daardoor lang niet altijd gemaakt. DOEL Beschrijven van praktische handvatten en stimuleren van het medisch-ethische denken bij patiëntgebonden onderzoek in de geestelijke gezondheidszorg. METHODE In dit artikel wordt een op de praktijkbehoefte gebaseerd overzicht van praktische handvatten en ethische overwegingen gegeven. RESULTATEN Dit artikel benadrukt dat onderzoekers reeds vóór de start van het onderzoek belangrijke afwegingen dienen te maken. Instructies daarvoor en richtlijnen voor medisch-ethische toetsing zijn te vinden in: het richtsnoer voor good clinical practice, het stroomschema van de Centrale Commissie Mensgebonden Onderzoek (ccmo) met de bijbehorende e-learningmodule en in de basiscursus ‘Regelgeving en organisatie voor klinisch onderzoekers’(brok). Praktische tips, geïllustreerd met voorbeelden, schetsen een kader om het medisch-ethisch denken te stimuleren. Tot slot is het van belang om de organisatorische inbedding van onderzoek in het kader van opleidingen te verbeteren. CONCLUSIE Basisinformatie over gcp en medisch-ethische toetsing bij patiëntgebonden onderzoek is via diverse kanalen beschikbaar. De uitdaging zit vooral in de inbedding van gcp in patiëntgebonden onderzoek door beginnend onderzoekers in de ggz.
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We read the invited review on sustainable medicines use in clinicalpractice by Adeyeye et al.1and would like to congratulate the authorswith the captivating way in which they used scientific facts combinedwith very practical solutions to convey their call to action. This call isprimarily addressed to the NHS, which the authors suspect will reso-nate with other health systems. While we fully agree with necessityof this top-down approach, we additionally believe that there is muchto be gained by making future prescribers more knowledgeable andaware about the impact they have on planetary health. The articleremains very brief about next generation of healthcare professionalsby quoting the General Medical Council's statement that“newly quali-fied doctors must be able to apply the principles, methods and knowl-edge of population health and the improvement of health andsustainable healthcare to medical practice.”2However, the underlyingquestion—how we effectively train future healthcare professionals inthese attitudes underpinned by knowledge—is not addressed...........
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Purpose Worry is an intuitive sense that goes beyond logical reasoning and is valuable in situations where patients’ conditions are rapidly changing or when objective data may not fully capture the complexity of a patient’s situation. Nurse anesthetists’ subjective reasons for worry are quite vague as they are valued inconsistently and not accurately expressed. This study aimed to identify factors playing a role in the emergence of worry during anesthesia practice to clarify its concept. Design Mixed-methods design consisting of quantitative online surveys followed by qualitative focus group interviews including Dutch nurse anesthetists. Methods Both quantitative and qualitative thematic analyses were performed, followed by data and methodological triangulation to enhance the validity and credibility of findings and mitigate the presence of bias. Findings Surveys (N = 102) were analyzed, and 14 nurse anesthetists participated in the focus group interviews. A total of 89% of the survey respondents reported that at least once have had the feeling of worry, of which 92% use worry during clinical anesthesia practice. Worry was mentioned to be a vital element during anesthesia practice that makes it possible to take precautionary actions to change the anesthetic care plan in a changing situation or patient deterioration. Conclusions While a clear definition of worry could not be given, it is a valuable element of anesthesia practice as it serves as a catalyst for critical thinking, problem-solving, clinical reasoning, and decision-making. Use of the feeling of worry alongside technological systems to make an informed decision is crucial. Technology has significantly improved the ability of health care providers to detect and respond to patient deterioration promptly, but it is crucial for nurse anesthetists to use their feeling of worry or intuition alongside technological systems and evidence-based practice to ensure quick assessments or judgments based on experience, knowledge, and observations in clinical practice.
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The main objective is to write a scientific paper in a peer-reviewed Open Access journal on the results of our feasibility study on increasing physical activity in home dwelling adults with chronic stroke. We feel this is important as this article aims to close a gap in the existing literature on behavioral interventions in physical therapy practice. Though our main target audience are other researchers, we feel clinical practice and current education on patients with stroke will benefit as well.
Youth care is under increasing pressure, with rising demand, longer waiting lists, and growing staff shortages. In the Netherlands, one in seven children and adolescents is currently receiving youth care. At the same time, professionals face high workloads, burnout risks, and significant administrative burdens. This combination threatens both the accessibility and quality of care, leading to escalating problems for young people and families. Artificial intelligence (AI) offers promising opportunities to relieve these pressures by supporting professionals in their daily work. However, many AI initiatives in youth care fail to move beyond pilot stages, due to barriers such as lack of user acceptance, ethical concerns, limited professional ownership, and insufficient integration into daily practice. Empirical research on how AI can be responsibly and sustainably embedded in youth care is still scarce. This PD project aims to develop practice-based insights and strategies that strengthen the acceptance and long-term adoption of AI in youth care, in ways that support professional practice and contribute to appropriate care. The focus lies not on the technology itself, but on how professionals can work with AI within complex, high-pressure contexts. The research follows a cyclical, participatory approach, combining three complementary implementation frameworks: the Implementation Guide (Kaptein), the CFIR model (Damschroder), and the NASSS-CAT framework (Greenhalgh). Three case studies serve as core learning environments: (1) a speech-to-text AI tool to support clinical documentation, (2) Microsoft Copilot 365 for organization-wide adoption in support teams, and (3) an AI chatbot for parents in high-conflict divorces. Throughout the project, professionals, clients, ethical experts, and organizational stakeholders collaborate to explore the practical, ethical, and organizational conditions under which AI can responsibly strengthen youth care services.
Over a million people in the Netherlands have type 2 diabetes (T2D), which is strongly related to overweight, and many more people are at-risk. A carbohydrate-rich diet and insufficient physical activity play a crucial role in these developments. It is essential to prevent T2D, because this condition is associated with a reduced quality of life, high healthcare costs and premature death due to cardiovascular diseases. The hormone insulin plays a major role in this. This hormone lowers the blood glucose concentration through uptake in body cells. If an excess of glucose is constantly offered, initially the body maintains blood glucose concentration within normal range by releasing higher concentrations of insulin into the blood, a condition that is described as “prediabetes”. In a process of several years, this compensating mechanism will eventually fail: the blood glucose concentration increases resulting in T2D. In the current healthcare practice, T2D is actually diagnosed by recognizing only elevated blood glucose concentrations, being insufficient for identification of people who have prediabetes and are at-risk to develop T2D. Although the increased insulin concentrations at normal glucose concentrations offer an opportunity for early identification/screening of people with prediabetes, there is a lack of effective and reliable methods/devices to adequately measure insulin concentrations. An integrated approach has been chosen for identification of people at-risk by using a prediabetes screening method based on insulin detection. Users and other stakeholders will be involved in the development and implementation process from the start of the project. A portable and easy-to-use demonstrator will be realised, based on rapid lateral flow tests (LFTs), which is able to measure insulin in clinically relevant samples (serum/blood) quickly and reliably. Furthermore, in collaboration with healthcare professionals, we will investigate how this screening method can be implemented in practice to contribute to a healthier lifestyle and prevent T2D.
