Abstract Background: Patients with glioma often suffer from cognitive deficits. Physical exercise has been effective in ameliorating cognitive deficits in older adults and neurological patients. This pilot randomized controlled trial (RCT) explored the possible impact of an exercise intervention, designed to improve cognitive functioning in glioma patients, regarding cognitive test performance and patient-reported outcomes (PROs). Methods: Thirty-four clinically stable patients with World Health Organization grades II/III glioma were randomized to a home-based remotely coached exercise group or an active control group. Patients exercised 3 times per week for 20-45 minutes, with moderate to vigorous intensity, during 6 months. At baseline and immediate follow-up, cognitive performance and PROs were assessed with neuropsychological tests and questionnaires, respectively. Linear regression analyses were used to estimate effect sizes of potential between-group differences in cognitive performance and PROs at 6 months. Results: The exercise group (n = 21) had small- to medium-sized better follow-up scores than the control group (n = 11) on several measures of attention and information processing speed, verbal memory, and executive function, whereas the control group showed a slightly better score on a measure of sustained selective attention. The exercise group also demonstrated small- to medium-sized better outcomes on measures of self-reported cognitive symptoms, fatigue, sleep, mood, and mental health-related quality of life. Conclusions: This small exploratory RCT in glioma patients provides a proof of concept with respect to improvement of cognitive functioning and PROs after aerobic exercise, and warrants larger exercise trials in brain tumor patients.
Purpose: This paper aims to define the influence of the physical and social dimensions of the work environment on knowledge productivity of academics in Dutch Universities of Applied Sciences.Design/methodology/approach: Literature review; a multiple case study based on literature review (6 cases); a survey (n=188).Findings: Knowledge workers share two basic needs: their productivity requires isolation (internalization of knowledge) and interaction (externalization of knowledge), supported by different spatial concepts. None of the work environments involved in the study adequately support all of the phases in the knowledge development process adequately. Collective productivity is primarily determined by the physical dimension of the workplace; whereas the social dimension is crucial for personal productivity. Social interaction has a stronger effect than distraction; and the layout has a stronger effect than comfort.Conclusions - A high performance workplace supports both externalization and internalization of knowledge, allowing group members to collaborate and communicate according to need. More traditional work environments support internalization; innovative workplace designs (the office as meeting place) are more suited to support interaction and collaboration. Discover why freedom of choice is the key.Recommendations - Academics should be allowed to choose as to how, where and when they work and involved during the development of new concepts.Paper type: Research paper
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Robots are increasingly used in a variety of work environments, but surprisingly little attention has been paid to how robots change work. In this comparative case study, we explore how robotization changed the work design of order pickers and order packers in eight logistic warehouses. We found that all warehouses robotized tasks based on technological functionality to increase efficiency, which sometimes created jobs consisting of ‘left-over tasks’. Only two warehouses used a bottom-up approach, where employees were involved in the implementation and quality of work was considered important. Although the other warehouses did not, sometimes their work design still benefitted from robotization. The positive effects we identified are reduced physical and cognitive demands and opportunities for upskilling. Warehouses that lack attention to the quality of work may risk ending up with the negative effects for employees, such as simplification and intensification of work, and reduced autonomy. We propose that understanding the consequences of robots on work design supports HR professionals to help managing this transition by both giving relevant input on a strategic level about the importance of work design and advocating for employees and their involvement.
Everyone has the right to participate in society to the best of their ability. This right also applies to people with a visual impairment, in combination with a severe or profound intellectual and possibly motor disability (VISPIMD). However, due to their limitations, for their participation these people are often highly dependent on those around them, such as family members andhealthcare professionals. They determine how people with VISPIMD participate and to what extent. To optimize this support, they must have a good understanding of what people with disabilities can still do with their remaining vision.It is currently difficult to gain insight into the visual abilities of people with disabilities, especially those with VISPIMD. As a professional said, "Everything we can think of or develop to assess the functional vision of this vulnerable group will help improve our understanding and thus our ability to support them. Now, we are more or less guessing about what they can see.Moreover, what little we know about their vision is hard to communicate to other professionals”. Therefore, there is a need for methods that can provide insight into the functional vision of people with VISPIMD, in order to predict their options in daily life situations. This is crucial knowledge to ensure that these people can participate in society to their fullest extent.What makes it so difficult to get this insight at the moment? Visual impairments can be caused by a range of eye or brain disorders and can manifest in various ways. While we understand fairly well how low vision affects a person's abilities on relatively simple visual tasks, it is much more difficult to predict this in more complex dynamic everyday situations such asfinding your way or moving around during daily activities. This is because, among other things, conventional ophthalmic tests provide little information about what people can do with their remaining vision in everyday life (i.e., their functional vision).An additional problem in assessing vision in people with intellectual disabilities is that many conventional tests are difficult to perform or are too fatiguing, resulting in either no or the wrong information. In addition to their visual impairment, there is also a very serious intellectual disability (possibly combined with a motor impairment), which makes it even more complex to assesstheir functional vision. Due to the interplay between their visual, intellectual, and motor disabilities, it is almost impossible to determine whether persons are unable to perform an activity because they do not see it, do not notice it, do not understand it, cannot communicate about it, or are not able to move their head towards the stimulus due to motor disabilities.Although an expert professional can make a reasonable estimate of the functional possibilities through long-term and careful observation, the time and correct measurement data are usually lacking to find out the required information. So far, it is insufficiently clear what people with VZEVMB provoke to see and what they see exactly.Our goal with this project is to improve the understanding of the visual capabilities of people with VISPIMD. This then makes it possible to also improve the support for participation of the target group. We want to achieve this goal by developing and, in pilot form, testing a new combination of measurement and analysis methods - primarily based on eye movement registration -to determine the functional vision of people with VISPIMD. Our goal is to systematically determine what someone is responding to (“what”), where it may be (“where”), and how much time that response will take (“when”). When developing methods, we take the possibilities and preferences of the person in question as a starting point in relation to the technological possibilities.Because existing technological methods were originally developed for a different purpose, this partly requires adaptation to the possibilities of the target group.The concrete end product of our pilot will be a manual with an overview of available technological methods (as well as the methods themselves) for assessing functional vision, linked to the specific characteristics of the target group in the cognitive, motor area: 'Given that a client has this (estimated) combination of limitations (cognitive, motor and attention, time in whichsomeone can concentrate), the order of assessments is as follows:' followed by a description of the methods. We will also report on our findings in a workshop for professionals, a Dutch-language article and at least two scientific articles. This project is executed in the line: “I am seen; with all my strengths and limitations”. During the project, we closely collaborate with relevant stakeholders, i.e. the professionals with specific expertise working with the target group, family members of the persons with VISPIMD, and persons experiencing a visual impairment (‘experience experts’).
Prompt and timely response to incoming cyber-attacks and incidents is a core requirement for business continuity and safe operations for organizations operating at all levels (commercial, governmental, military). The effectiveness of these measures is significantly limited (and oftentimes defeated altogether) by the inefficiency of the attack identification and response process which is, effectively, a show-stopper for all attack prevention and reaction activities. The cognitive-intensive, human-driven alarm analysis procedures currently employed by Security Operation Centres are made ineffective (as opposed to only inefficient) by the sheer amount of alarm data produced, and the lack of mechanisms to automatically and soundly evaluate the arriving evidence to build operable risk-based metrics for incident response. This project will build foundational technologies to achieve Security Response Centres (SRC) based on three key components: (1) risk-based systems for alarm prioritization, (2) real-time, human-centric procedures for alarm operationalization, and (3) technology integration in response operations. In doing so, SeReNity will develop new techniques, methods, and systems at the intersection of the Design and Defence domains to deliver operable and accurate procedures for efficient incident response. To achieve this, this project will develop semantically and contextually rich alarm data to inform risk-based metrics on the mounting evidence of incoming cyber-attacks (as opposed to firing an alarm for each match of an IDS signature). SeReNity will achieve this by means of advanced techniques from machine learning and information mining and extraction, to identify attack patterns in the network traffic, and automatically identify threat types. Importantly, SeReNity will develop new mechanisms and interfaces to present the gathered evidence to SRC operators dynamically, and based on the specific threat (type) identified by the underlying technology. To achieve this, this project unifies Dutch excellence in intrusion detection, threat intelligence, and human-computer interaction with an industry-leading partner operating in the market of tailored solutions for Security Monitoring.
