The primary aims of this study were (1) to evaluate whole-body mechanical efficiency (ME) in a large group of chronic obstructive pulmonary disease (COPD) patients with a wide range of degrees of illness and (2) to examine how ME in COPD is related to absolute work rate and indices of disease severity during exercise testing. A total of 569 patients (301 male patients; GOLD stage I: 28, GOLD stage II: 166, GOLD stage III: 265, and GOLD stage IV: 110) with chronic obstructive pulmonary disease (COPD) were included in the data analysis. Individual maximal workload (watt), peak minute ventilation ((Equation is included in full-text article.)E, L/min body temperature and pressure, saturated), and peak oxygen uptake ((Equation is included in full-text article.)O2, mL/min standard temperature and pressure, dry) were determined from a maximal incremental cycle ergometer test. Ventilatory and metabolic response parameters were collected during a constant work rate test at 75% of the individual maximal workload. From the exercise responses of the constant work rate test, the gross ME was calculated. The mean whole-body gross ME was 11.0 ± 3.5% at 75% peak power. The ME declined significantly (P < .001) with increasing severity of the disease when measured at the same relative power. Log-transformed absolute work rate (r = .87, P < .001) was the strongest independent predictor of gross ME. Body mass was the single other variable that contributed significantly to the linear regression model. Gross ME in COPD was largely predicted by the absolute work rate (r = .87; P < .001) while indices of the severity of the disease did not predict ME in COPD.
Player behavioural modelling has grown from a means to improve the playing strength of computer programs that play classic games (e.g., chess), to a means for impacting the player experience and satisfaction in video games, as well as in cross-domain applications such as interactive storytelling. In this context, player behavioural modelling is concerned with two goals, namely (1) providing an interesting or effective game AI on the basis of player models and (2) creating a basis for game developers to personalise gameplay as a whole, and creating new user-driven game mechanics. In this article, we provide an overview of player behavioural modelling for video games by detailing four distinct approaches, namely (1) modelling player actions, (2) modelling player tactics, (3) modelling player strategies, and (4) player profiling. We conclude the article with an analysis on the applicability of the approaches for the domain of video games.
An important performance determinant in wheelchair sports is the power exchanged between the athletewheelchair combination and the environment, in short, mechanical power. Inertial measurement units (IMUs) might be used to estimate the exchanged mechanical power during wheelchair sports practice. However, to validly apply IMUs for mechanical power assessment in wheelchair sports, a well-founded and unambiguous theoretical framework is required that follows the dynamics of manual wheelchair propulsion. Therefore, this research has two goals. First, to present a theoretical framework that supports the use of IMUs to estimate power output via power balance equations. Second, to demonstrate the use of the IMU-based power estimates during wheelchair propulsion based on experimental data. Mechanical power during straight-line wheelchair propulsion on a treadmill was estimated using a wheel mounted IMU and was subsequently compared to optical motion capture data serving as a reference. IMU-based power was calculated from rolling resistance (estimated from drag tests) and change in kinetic energy (estimated using wheelchair velocity and wheelchair acceleration). The results reveal no significant difference between reference power values and the proposed IMU-based power (1.8% mean difference, N.S.). As the estimated rolling resistance shows a 0.9–1.7% underestimation, over time, IMU-based power will be slightly underestimated as well. To conclude, the theoretical framework and the resulting IMU model seems to provide acceptable estimates of mechanical power during straight-line wheelchair propulsion in wheelchair (sports) practice, and it is an important first step towards feasible power estimations in all wheelchair sports situations.
Introduction The research group Biobased Resources & Energy (BRE) of Avans focusses on recovery of valuable building blocks from low-value solid and liquid residual streams from agriculture, households and industries. For the valorisation of these residual streams, BRE looks into different biological, chemical and mechanical processes. One of the main issues in the utilisation of residual streams is economic feasibility and the recovery of multiple resources from one residual stream. Using membrane technologies in combination with biological, chemical and/or mechanical processes could offer great opportunities. Central Research Question What is the applicability of membrane technologies for valorisation of different residual streams and is it possible to integrate membrane technology in current and new biorefining projects of research group BRE: Set-up In order to reach the goal of this postdoc, 4 research questions will be answered using literature search, experimentation and modelling: 1) What membrane methods are currently (commercially) available to enhance the results of current projects in research group BRE? 2) What are the essential technical parameters for membrane separation and how can these be optimized? 3) What is the economic impact of using membrane technology in recovery of valuable building blocks from residual streams? 4) What are the effects of using membranes instead of or complementary to currently used methods on the sustainability of valorisation of residual streams? Cooperation The postdoc and the research group BRE want to extend the contact and research cooperation with (regional) businesses and (applied) universities and support and facilitate the introduction and further development of membrane technologies in the curriculum of different Avans study programmes. This will be done via internships, minor projects (together with businesses) and development of study material for courses and trainings.
The Ph.D. candidate will investigate the seismic response of connection details frequently used in traditional Dutch construction practice, specifically in the Groningen area. The research will focus on the experimental and numerical definition of the complete load-deflection behaviour of each considered connection; specifically, the tests will aim at identifying stiffness, strength, ductility, and dissipative behaviour of the connections. The experiments will be conducted on scaled or full-scale components that properly resemble the as-built and retrofitted as well connection details. The tests will involve monotonic and cyclic loading protocols to be able to define the load and displacement response of the connection to reversal loads, such as earthquakes, as well as the development of failure mechanisms under such loading cases. Possibly, also dynamic tests will be performed. Numerical models will be created and calibrated versus the experimental findings. Characteristic hysteretic behaviours of the examined connection types will be provided for the use of engineers and researchers.
The postdoc candidate, Sondos Saad, will strengthen connections between research groups Asset Management(AM), Data Science(DS) and Civil Engineering bachelor programme(CE) of HZ. The proposed research aims at deepening the knowledge about the complex multidisciplinary performance deterioration prediction of turbomachinery to optimize cleaning costs, decrease failure risk and promote the efficient use of water &energy resources. It targets the key challenges faced by industries, oil &gas refineries, utility companies in the adoption of circular maintenance. The study of AM is already part of CE curriculum, but the ambition of this postdoc is that also AM principles are applied and visible. Therefore, from the first year of the programme, the postdoc will develop an AM material science line and will facilitate applied research experiences for students, in collaboration with engineering companies, operation &maintenance contractors and governmental bodies. Consequently, a new generation of efficient sustainability sensitive civil engineers could be trained, as the labour market requires. The subject is broad and relevant for the future of our built environment being more sustainable with less CO2 footprint, with possible connections with other fields of study, such as Engineering, Economics &Chemistry. The project is also strongly contributing to the goals of the National Science Agenda(NWA), in themes of “Circulaire economie en grondstoffenefficiëntie”,”Meten en detecteren: altijd, alles en overall” &”Smart Industry”. The final products will be a framework for data-driven AM to determine and quantify key parameters of degradation in performance for predictive AM strategies, for the application as a diagnostic decision-support toolbox for optimizing cleaning &maintenance; a portfolio of applications &examples; and a new continuous learning line about AM within CE curriculum. The postdoc will be mentored and supervised by the Lector of AM research group and by the study programme coordinator(SPC). The personnel policy and job function series of HZ facilitates the development opportunity.
