We tested the hypothesis that in human ageing a decreased intramuscular acylcarnitine status is associated with (pre-)frailty, reduced physical performance and altered mitochondrial function. Results showed that intramuscular total carnitine levels and acetylcarnitine levels were lower in (pre-)frail old females compared to fit old females and young females, whereas no differences were observed in males. The low intramuscular acetylcarnitine levels in females correlated with low physical performance, even after correction for muscle mass (%), and were accompanied with lowered expression of genes involved in mitochondrial energy production and functionality. We concluded that in (pre-)frail old females, intramuscular total carnitine levels and acetylcarnitine levels are decreased, and this decrease is associated with reduced physical performance and low expression of a wide range of genes critical for mitochondrial function. The results stress the importance of taking sex differences into account in ageing research.
MULTIFILE
The research examined the ways in which Student Generated Video supported the learning process on the course ‘Levensbeschouwing’ (Life Philosophy) on the third year on the teacher training course at Inholland in Amsterdam. The central question examined was: In which ways does the student generated video on the Inholland course ‘Life Philosophy’ contribute to students gaining insight, developing deeper knowledge, and achieving the course learning goals? The 30 students on the course participated in the research. During the course, they were involved in creating three video interviews per project group that examined the question of life philosophy from the perspective of personal life, life philosophy traditions and school life. Video production was segmented into four phases; pre-production, production, post-production and reflection. At each phase, students answered short open questions online, and on the final day completed a survey. A group of seven students participated in a group interview on the final day.
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The European Union is striving for a high penetration of renewable energy production in the future energy grid. Currently, the EU energy directive is aiming for 20% renewable energy production in the year 2020. In future plans the EU strives for approximately 80% renewable energy production by the year 2050. However, high penetration of wind and solar PV energy production, both centrally and de-centrally, can possibly destabilize the electricity grid. The gas grid and the flexibility of gas, which can be transformed in both electricity and heat at different levels of scale, can help integrate and balance intermittent renewable production. One possible method of assisting the electricity grid in achieving and maintaining balance is by pre-balancing local decentralized energy grids. Adopting flexible gas based decentralized energy production can help integrate intermittent renewable electricity production, short lived by-products (e.g. heat) and at the same time minimize transport of energy carriers and fuel sources. Hence, decentralized energy grids can possibly improve the overall efficiency and sustainability of the energy distribution system. The flexibility aforementioned, can potentially give gas a pivotal role in future decentralized energy grids as load balancer. However, there are a lot of potentially variables which effect a successful integration of renewable intermittent production and load balancing within decentralized energy systems. The flexibility of gas in general opens up multiple fuel sources e.g., natural gas, biogas, syngas etc. and multiple possibilities of energy transformation pathways e.g. combined heat and power, fuel cells, high efficiency boilers etc. Intermittent renewable production is already increasing exponentially on the decentralized level where load balancing is still lacking.
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An Erasmus+ funded project in which universities from Denmark, Norway, and Portugal work alongside BUas to research and develop pre-preproduction teaching materials regarding the use of Virtual Production (VP) technologies. Lecturers and students from the consortium will get hands-on experience with BUas's XR stage, with the goals of collaboration and understanding of the needs of future media professionals.