Lessons learned on the progress towards 4th generation district heating (4DHC) are presented from 6 pilot implementation projects in the UK, Ireland, Belgium, France, and the Netherlands (HeatNet project). The pilots have implemented the infrastructure for district heating from various (waste) heat and renewable sources to reduce CO2 emissions. With the development of long term road maps, progress is made towards the role out of 4DHC in the regions. The pilots have a different level of experience with district heating and transnational learning is specifically addressed. Purpose of the evaluation of the pilots is to give local authorities insight into barriers and solutions and the way they are closely linked to stakeholders in their geographical, politicaland cultural context in NWE. To do this, the financial, regulatory and organisational barriers the pilots face and possible solutions that were shared between the pilots are analysed in the context of system innovation. Differences in national and regional contexts have been analysed to be able to generalise solutions to a level they can be used in a different context. We will confront the pilot’s development with best and worst practice from literature and score Key Success Factors.
MULTIFILE
Out-of-plane (OOP) collapse is one of the most observed damage types in masonry structures during strong earthquakes. OOP strength of a masonry wall depends on several parameters such as the dimensions of the wall, vertical restoring force, boundary conditions and material properties, which are parameters creating complex kinematics during an earthquake. Testing of OOP response of a masonry wall is thus a challenging task, also because additional to the complexities mentioned, the seismic forces triggering OOP are caused by inertia of the wall itself, a phenomenon that needs dynamic testing. All these facts make shake table tests of masonry walls for capturing the OOP response extremely relevant. This paper presents shake table tests on a total of four wall specimens, two of which were reference walls and the other two were strengthened solid masonry walls. The tested walls built to represent the characteristics of Groningen houses built before the Second World War and also the historical masonry structures in the region. The strengthening methods applied are the deep-mounted carbon strips embedded in flexible epoxy and helical bars applied in mortar beds. The shake table tests presented here show that OOP specimens not including the additional masses imposed by the floors may oversee important kinematic response characteristics of the walls. Furthermore, tests have also shown that even serious cracks caused by OOP response close when the shaking stops, which causes damage on the walls and significant decrease in the stiffness, but they are extremely difficult to be caught by human inspection. This has consequences in terms of ongoing damage inspection and compensation efforts taking place in the Groningen gas field. The strengthening methods applied to the two specimens have shown clear improvement in strength, and a partial improvement in progression of damage.
Although poor reading and spelling skills have been associated with weak skills of executive functioning (EF), its role in literacy is not undisputed. Because EF has different theoretical underpinnings, methods of analysis and of assessing EF, it has led to varying and often contrasting results in its effects in children with dyslexia. The present study has two goals. The first goal is to establish the relationship between a large number of EF tasks and reading and spelling skills in a large number of Dutch dyslexic children (n = 229). More interesting, however, is the second aim. To what extent do EF skills predict progress in reading and spelling in dyslexic children who attend a remediation program? The results reveal small, but significant relationships between EF and reading and spelling skills, but no relationships between EF and progress in reading and spelling. It is concluded that training EF skills is unlikely to enhance reading and spelling skills.
MULTIFILE
Mode heeft een cruciale functie in de samenleving: zij maakt diversiteit en inclusiviteit mogelijk en is een middel voor individuen om zich uit te drukken. Desalniettemin is mode ook een raadsel op het gebied van duurzaamheid, zowel aan de sociale als aan de milieukant. Er bestaan echter alternatieven voor de huidige praktijken in de mode. Dit project heeft tot doel de ontwikkeling van een van die initiatieven te ondersteunen. In samenwerking met twee Nederlandse MKB bedrijven in de mode-industrie, willen we een of meer business modellen co-designen voor het vermarkten van circulair ontworpen laser geprinte T-shirts. Door lasertechnologie te introduceren in plaats van traditionele inktopties, kunnen de T- shirts hun CO2 voetafdruk verder verkleinen en een verstandig alternatief zijn voor individuen, die op zoek zijn naar duurzame modekeuzes. Maar hoewel de technologische haalbaarheid vaststaat, vereist het vermarkten sterke, schaalbare, bedrijfsmodellen. Via een haalbaarheidsstudie willen we dergelijke businessmodellen ontwikkelen en de commercialisering van deze producten ondersteunen. Wij zijn van plan de reacties van de consument op een dergelijke innovatie te bestuderen, evenals de belemmeringen en stimulansen vanuit het oogpunt van de consument, en de inkoop-, toeleveringsketen- en financiële kwesties die kunnen voortvloeien uit de schaalbaarheid van een potentieel bedrijfsmodel. Om praktische relevantie voor de bredere industrie te verzekeren, streven we ernaar om de resultaten te presenteren op evenementen georganiseerd door een van de consortiumpartners (in 2023), als ook om een teaching case en een wetenschappelijk artikel te ontwikkelen op basis van de resultaten van het project.
Organ-on-a-chip technology holds great promise to revolutionize pharmaceutical drug discovery and development which nowadays is a tremendously expensive and inefficient process. It will enable faster, cheaper, physiologically relevant, and more reliable (standardized) assays for biomedical science and drug testing. In particular, it is anticipated that organ-on-a-chip technology can substantially replace animal drug testing with using the by far better models of true human cells. Despite this great potential and progress in the field, the technology still lacks standardized protocols and robust chip devices, which are absolutely needed for this technology to bring the abovementioned potential to fruition. Of particular interest is heart-on-a-chip for drug and cardiotoxicity screening. There is presently no preclinical test system predicting the most important features of cardiac safety accurately and cost-effectively. The main goal of this project is to fabricate standardized, robust generic heart-on-a-chip demonstrator devices that will be validated and further optimized to generate new physiologically relevant models to study cardiotoxicity in vitro. To achieve this goal various aspects will be considered, including (i) the search for alternative chip materials to replace PDMS, (ii) inner chip surface modification and treatment (chemistry and topology), (iii) achieving 2D/3D cardiomyocyte (long term) cell culture and cellular alignment within the chip device, (iv) the possibility of integrating in-line sensors in the devices and, finally, (v) the overall chip design. The achieved standardized heart-on-a-chip technology will be adopted by pharmaceutical industry. This proposed project offers a unique opportunity for the Netherlands, and Twente in particular, which has relevant expertise, potential, and future perspective in this field as it hosts world-leading companies pioneering various core aspects of the technology that are relevant for organs-on-chips, combined with two world-leading research institutes within the University of Twente.
Post-earthquake structural damage shows that wall collapse is one of the most common failure mechanisms in unreinforced masonry buildings. It is expected to be a critical issue also in Groningen, located in the northern part of the Netherlands, where human-induced seismicity has become an uprising problem in recent years. The majority of the existing buildings in that area are composed of unreinforced masonry; they were not designed to withstand earthquakes since the area has never been affected by tectonic earthquakes. They are characterised by vulnerable structural elements such as slender walls, large openings and cavity walls. Hence, the assessment of unreinforced masonry buildings in the Groningen province has become of high relevance. The abovementioned issue motivates engineering companies in the region to research seismic assessments of the existing structures. One of the biggest challenges is to be able to monitor structures during events in order to provide a quick post-earthquake assessment hence to obtain progressive damage on structures. The research published in the literature shows that crack detection can be a very powerful tool as an assessment technique. In order to ensure an adequate measurement, state-of-art technologies can be used for crack detection, such as special sensors or deep learning techniques for pixel-level crack segmentation on masonry surfaces. In this project, a new experiment will be run on an in-plane test setup to systematically propagate cracks to be able to detect cracks by new crack detection tools, namely digital crack sensor and vision-based crack detection. The validated product of the experiment will be tested on the monument of Fraeylemaborg.
