From the article: Abstract Adjustment and testing of a combination of stochastic and nonstochastic observations is applied to the deformation analysis of a time series of 3D coordinates. Nonstochastic observations are constant values that are treated as if they were observations. They are used to formulate constraints on the unknown parameters of the adjustment problem. Thus they describe deformation patterns. If deformation is absent, the epochs of the time series are supposed to be related via affine, similarity or congruence transformations. S-basis invariant testing of deformation patterns is treated. The model is experimentally validated by showing the procedure for a point set of 3D coordinates, determined from total station measurements during five epochs. The modelling of two patterns, the movement of just one point in several epochs, and of several points, is shown. Full, rank deficient covariance matrices of the 3D coordinates, resulting from free network adjustments of the total station measurements of each epoch, are used in the analysis.
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The Utrecht School of Journalism has a long tradition in international higher education. The School’s European Culture & European Journalism (ED&EJ) programme is an example of a pedagogical practice in higher education where advanced students learn how to perform in an international context. Journalism students from Moscow to Ottawa and from Helsinki to Bilbao learn alongside Dutch students. It is not only the content of the programme and the reporting for the Web Magazine that makes the EC&EJ programme an inspirational educational experience. The programme demonstrates the importance of sharing different professional and cultural values. This sharing and confronting of professional standards contributes to an important new qualification for all higher educated professionals: awareness of cultural differences and similarities
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Evaluation of the hydrological performance of grassed swales usually needs long-term monitoring data. At present, suitable techniques for simulating the hydrological performance using limited monitoring data are not available. Therefore, current study aims to investigate the relationship between saturated hydraulic conductivity (Ks) fitting results and rainfall characteristics of various events series length. Data from a full-scale grassed swale (Enschede, the Netherlands) were utilized as long-term rainfall event series length (95 rainfall events) on the fitting outcomes. Short-term rainfall event series were extracted from these long-term series and used as input in fitting into a multivariate nonlinear model between Ks and its influencing rainfall indicators (antecedent dry days, temperature, rainfall, rainfall duration, total rainfall, and seasonal factor (spring, summer, autumn, and winter, herein refer as 1, 2, 3, and 4). Comparison of short-term and long-term rainfall event series fitting results allowed to obtain a representative short-term series that leads to similar results with those using long-term series. A cluster analysis was conducted based on the fitting results of the representative rainfall event series with their rainfall event characteristics using average values of influencing rainfall indicators. The seasonal index (average value of seasonal factors) was found to be the most representative short rainfall event series indicator. Furthermore, a Bayesian network was proposed in the current study to predict if a given short-term rainfall event series is representative. It was validated by a data series (58 rainfall events) from another full-scale grassed swale located in Utrecht, the Netherlands. Results revealed that it is quite promising and useful to evaluate the representativeness of short-term rainfall event series used for long-term hydrological performance evaluation of grassed swales.
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Completeness of data is vital for the decision making and forecasting on Building Management Systems (BMS) as missing data can result in biased decision making down the line. This study creates a guideline for imputing the gaps in BMS datasets by comparing four methods: K Nearest Neighbour algorithm (KNN), Recurrent Neural Network (RNN), Hot Deck (HD) and Last Observation Carried Forward (LOCF). The guideline contains the best method per gap size and scales of measurement. The four selected methods are from various backgrounds and are tested on a real BMS and metereological dataset. The focus of this paper is not to impute every cell as accurately as possible but to impute trends back into the missing data. The performance is characterised by a set of criteria in order to allow the user to choose the imputation method best suited for its needs. The criteria are: Variance Error (VE) and Root Mean Squared Error (RMSE). VE has been given more weight as its ability to evaluate the imputed trend is better than RMSE. From preliminary results, it was concluded that the best K‐values for KNN are 5 for the smallest gap and 100 for the larger gaps. Using a genetic algorithm the best RNN architecture for the purpose of this paper was determined to be GatedRecurrent Units (GRU). The comparison was performed using a different training dataset than the imputation dataset. The results show no consistent link between the difference in Kurtosis or Skewness and imputation performance. The results of the experiment concluded that RNN is best for interval data and HD is best for both nominal and ratio data. There was no single method that was best for all gap sizes as it was dependent on the data to be imputed.
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Reversed-phase HPLC with mass spectrometric and diode array detection as well as some literature data were used to reveal the individual types of solutes in anthocyanin complexes of tulip flower petals that are responsible for tulip flower petals coloration of the samples available in the local flower market. It has been found that the main components of the complexes are 3-rutinosides and their 2”’ and 3”’ acylated with acetic acid derivatives of the three anthocyanidins - delphinidin, cyanidin and pelargonidin in the color dependent ratios, though trace quantities of 3-glucosides were found in some cases. For the anthocyanin structure confirmation a correlation analysis of solute retentions of cyanidin or pelargonidin derivatives vs that of delphinidin was proposed based upon equivalence of structures alteration in the solute pairs for each series. The specificity of solutes retention modes was revealed by relative retention analysis, the trend parameters reflected particularities of chromatographic behavior as well as that of electron spectra of the solutes. The difference of acylated anthocyanins retentions was proposed to disclose the conformation states of solutes in the sorbent interface.
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In December of 2004 the Directorate General for Research and Technological Development (DG RTD) of the European Commission (EC) set up a High-Level Expert Group to propose a series of measures to stimulate the reporting of Intellectual Capital in research intensive Small and Medium-Sized Enterprises (SMEs). The Expert Group has focused on enterprises that either perform Research and Development (R&D), or use the results of R&D to innovate and has also considered the implications for the specialist R&D units of larger enterprises, dedicated Research & Technology Organizations and Universities. In this report the Expert Group presents its findings, leading to six recommendations to stimulate the reporting of Intellectual Capital in SMEs by raising awareness, improving reporting competencies, promoting the use of IC Reporting and facilitating standardization.
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Completeness of data is vital for the decision making and forecasting on Building Management Systems (BMS) as missing data can result in biased decision making down the line. This study creates a guideline for imputing the gaps in BMS datasets by comparing four methods: K Nearest Neighbour algorithm (KNN), Recurrent Neural Network (RNN), Hot Deck (HD) and Last Observation Carried Forward (LOCF). The guideline contains the best method per gap size and scales of measurement. The four selected methods are from various backgrounds and are tested on a real BMS and meteorological dataset. The focus of this paper is not to impute every cell as accurately as possible but to impute trends back into the missing data. The performance is characterised by a set of criteria in order to allow the user to choose the imputation method best suited for its needs. The criteria are: Variance Error (VE) and Root Mean Squared Error (RMSE). VE has been given more weight as its ability to evaluate the imputed trend is better than RMSE. From preliminary results, it was concluded that the best K‐values for KNN are 5 for the smallest gap and 100 for the larger gaps. Using a genetic algorithm the best RNN architecture for the purpose of this paper was determined to be Gated Recurrent Units (GRU). The comparison was performed using a different training dataset than the imputation dataset. The results show no consistent link between the difference in Kurtosis or Skewness and imputation performance. The results of the experiment concluded that RNN is best for interval data and HD is best for both nominal and ratio data. There was no single method that was best for all gap sizes as it was dependent on the data to be imputed.
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Background: Follow‑up of curatively treated primary breast cancer patients consists of surveillance and aftercare and is currently mostly the same for all patients. A more personalized approach, based on patients’ individual risk of recurrence and personal needs and preferences, may reduce patient burden and reduce (healthcare) costs. The NABOR study will examine the (cost‑)effectiveness of personalized surveillance (PSP) and personalized aftercare plans (PAP) on patient‑reported cancer worry, self‑rated and overall quality of life and (cost‑)effectiveness. Methods: A prospective multicenter multiple interrupted time series (MITs) design is being used. In this design, 10 participating hospitals will be observed for a period of eighteen months, while they ‑stepwise‑ will transit from care as usual to PSPs and PAPs. The PSP contains decisions on the surveillance trajectory based on individual risks and needs, assessed with the ‘Breast Cancer Surveillance Decision Aid’ including the INFLUENCE prediction tool. The PAP contains decisions on the aftercare trajectory based on individual needs and preferences and available care resources, which decision‑making is supported by a patient decision aid. Patients are non‑metastasized female primary breast cancer patients (N= 1040) who are curatively treated and start follow‑up care. Patient reported outcomes will be measured at five points in time during two years of follow‑up care (starting about one year after treatment and every six months thereafter). In addition, data on diagnostics and hospital visits from patients’ Electronical Health Records (EHR) will be gathered. Primary outcomes are patient‑reported cancer worry (Cancer Worry Scale) and over‑all quality of life (as assessed with EQ‑VAS score). Secondary outcomes include health care costs and resource use, health‑related quality of life (as measured with EQ5D‑5L/SF‑12/EORTC‑QLQ‑C30), risk perception, shared decision‑making, patient satisfaction, societal participation, and cost‑effectiveness. Next, the uptake and appreciation of personalized plans and patients’ experiences of their decision‑making process will be evaluated. Discussion: This study will contribute to insight in the (cost‑)effectiveness of personalized follow‑up care and contributes to development of uniform evidence‑based guidelines, stimulating sustainable implementation of personalized surveillance and aftercare plans. Trial registration: Study sponsor: ZonMw. Retrospectively registered at ClinicalTrials.gov (2023), ID: NCT05975437.
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eHealth education should be integrated into vocational training and continuous professional development programmes. In this opinion article, we aim to support organisers of Continuing Professional Development (CPD) and teachers delivering medical vocational training by providing recommendations for eHealth education. First, we describe what is required to help primary care professionals and trainees learn about eHealth. Second, we elaborate on how eHealth education might be provided
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With summaries in Dutch, Esperanto and English. DOI: 10.4233/uuid:d7132920-346e-47c6-b754-00dc5672b437 "The subject of this study is deformation analysis of the earth's surface (or part of it) and spatial objects on, above or below it. Such analyses are needed in many domains of society. Geodetic deformation analysis uses various types of geodetic measurements to substantiate statements about changes in geometric positions.Professional practice, e.g. in the Netherlands, regularly applies methods for geodetic deformation analysis that have shortcomings, e.g. because the methods apply substandard analysis models or defective testing methods. These shortcomings hamper communication about the results of deformation analyses with the various parties involved. To improve communication solid analysis models and a common language have to be used, which requires standardisation.Operational demands for geodetic deformation analysis are the reason to formulate in this study seven characteristic elements that a solid analysis model needs to possess. Such a model can handle time series of several epochs. It analyses only size and form, not position and orientation of the reference system; and datum points may be under influence of deformation. The geodetic and physical models are combined in one adjustment model. Full use is made of available stochastic information. Statistical testing and computation of minimal detectable deformations is incorporated. Solution methods can handle rank deficient matrices (both model matrix and cofactor matrix). And, finally, a search for the best hypothesis/model is implemented. Because a geodetic deformation analysis model with all seven elements does not exist, this study develops such a model.For effective standardisation geodetic deformation analysis models need: practical key performance indicators; a clear procedure for using the model; and the possibility to graphically visualise the estimated deformations."
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