In the fall of 1999, an international integrated product development pilot project based on collaborative engineering was started with team members in two international teams from the United States, The Netherlands and Germany. Team members interacted using various Internet capabilities, including, but not limited to, ICQ (means: I SEEK YOU, an internet feature which immediately detects when somebody comes "on line"), web phones, file servers, chat rooms and Email along with video conferencing. For this study a control group with all members located in the USA only also worked on the same project.
In the current discourses on sustainable development, one can discern two main intellectual cultures: an analytic one focusing on measuring problems and prioritizing measures, (Life Cycle Analysis (LCA), Mass Flow Analysis (MFA), etc.) and; a policy/management one, focusing on long term change, change incentives, and stakeholder management (Transitions/niches, Environmental economy, Cleaner production). These cultures do not often interact and interactions are often negative. However, both cultures are required to work towards sustainability solutions: problems should be thoroughly identified and quantified, options for large change should be guideposts for action, and incentives should be created, stakeholders should be enabled to participate and their values and interests should be included in the change process. The paper deals especially with engineering education. Successful technological change processes should be supported by engineers who have acquired strategic competences. An important barrier towards training academics with these competences is the strong disciplinarism of higher education. Raising engineering students in strong disciplinary paradigms is probably responsible for their diminishing public engagement over the course of their studies. Strategic competences are crucial to keep students engaged and train them to implement long term sustainable solutions.
This paper extends the use of a framework identifying four types of barriers to lifelong learning (LLL): institutional, situational, dispositional, and informational. Initially applied to Nordic universities, the framework is now used to interview global stakeholders about LLL provisioning. The study explores commonalities and differences across regions, and the frameworkandapos;s potential to highlight key barriers and enablers, informing strategic and policy changes. The countries involved are Denmark, Norway, Finland, Holland, and Singapore. Following the description from each country, it identifies institutional, situational, dispositional, and informational barriers, which are interrelated and influence LLL in a more global context. Challenges include funding, balancing job and family commitments, and the need for a learnercentric approach. The study reveals that LLL plays a minor role in universities, with insufficient encouragement despite being included in strategies. Major obstacles include restrictive legislation, bureaucratic boundaries, and unstable funding models. Overcoming these could enable nationwide or transnational platforms for LLL.
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Due to the existing pressure for a more rational use of the water, many public managers and industries have to re-think/adapt their processes towards a more circular approach. Such pressure is even more critical in the Rio Doce region, Minas Gerais, due to the large environmental accident occurred in 2015. Cenibra (pulp mill) is an example of such industries due to the fact that it is situated in the river basin and that it has a water demanding process. The current proposal is meant as an academic and engineering study to propose possible solutions to decrease the total water consumption of the mill and, thus, decrease the total stress on the Rio Doce basin. The work will be divided in three working packages, namely: (i) evaluation (modelling) of the mill process and water balance (ii) application and operation of a pilot scale wastewater treatment plant (iii) analysis of the impacts caused by the improvement of the process. The second work package will also be conducted (in parallel) with a lab scale setup in The Netherlands to allow fast adjustments and broaden evaluation of the setup/process performance. The actions will focus on reducing the mill total water consumption in 20%.
In the context of global efforts to increase sustainability and reduce CO2 emissions in the chemical industry, bio-based materials are receiving increasing attention as renewable alternatives to petroleum-based polymers. In this regard, Visolis has developed a bio-based platform centered around the efficient conversion of plant-derived sugars to mevalonolactone (MVL) via microbial fermentation. Subsequently, MVL is thermochemically converted to bio-monomers such as isoprene and 3-methyl-1,5-pentane diol, which are ultimately used in the production of polymer materials. Currently, the Visolis process has been optimized to use high-purity, industrial dextrose (glucose) as feedstock for their fermentation process. Dutch Sustainable Development (DSD) has developed a direct processing technology in which sugar beets are used for fermentation without first having to go through sugar extraction and refinery. The main exponent of this technology is their patented Betaprocess, in which the sugar beet is essentially exposed to heat and a mild vacuum explosion, opening the cell walls and releasing the sugar content. This Betaprocess has the potential to speed up current fermentation processes and lower feedstock-related costs. The aim of this project is to combine aforementioned technologies to enable the production of mevalonolactone using sucrose, present in crude sugar beet bray after Betaprocessing. To this end, Zuyd University of Applied Sciences (Zuyd) intends to collaborate with Visolis and DSD. Zuyd will utilize its experience in both (bio)chemical engineering and fermentation to optimize the process from sugar beet (pre)treatment to product recovery. Visolis and DSD will contribute their expertise in microbial engineering and low-cost sugar production. During this collaboration, students and professionals will work together at the Chemelot Innovation and Learning Labs (CHILL) on the Brightlands campus in Geleen. This collaboration will not only stimulate innovation and sustainable chemistry, but also provides starting professionals with valuable experience in this expanding field.
The global market for the industrial manufacturing of recombinant proteins (RPS) is steadily increasing and demand will keep rising in years to come. Currently, RPs are already an integral part of disease therapeutics, agriculture and the chemical industry and RP manufacturing methods rely heavily on host systems such as prokaryotes and, to a lesser extent, mammalian, yeast and plant cells. When comparing these host systems, all have their specific strengths and weaknesses and numerous challenges remain to improve protein manufacturing on an industrial scale. In this project, GLO Biotics proposes an innovative plant-based RP expression platform with the potential of significantly reducing costs and process requirements compared to the current state-of-the-art systems. Specifically, this novel concept is based on the use of coconut water as a natural, cell-free ‘protein production factory’. Coconut water in nuts aged 4-6 months is composed of free-floating cell nuclei devoid of cell walls, and it has been demonstrated these nuclei can express foreign proteins. Compared to existing platforms, the relative ease of delivering foreign protein-coding genes into this system, as well as the ease of recovery of the produced protein, potentially offers an innovative platform with great commercial attractiveness. In summary, the aim of this project is to provide a proof-of-concept for coconut water as a novel and competitive RP production platform by demonstrating the production and recovery of several commercially available RPs. To this end, GLO Biotics intends to collaborate with Zuyd University of Applied Sciences (Zuyd) and the Aachen Maastricht Institute for Biobased Materials (AMIBM) in demonstrating the potential of the ‘GLO-Conuts’ expression system. As a consortium, Zuyd and GLO Biotics will utilize their shared experience in molecular engineering and DNA vector technology and AMIBM will bring their expertise in plant-based RP production and recovery.
