We developed and piloted a course, called Changemakers, that supported interdisciplinary student-led action groups to identify social and environmental sustainability challenges and influence systemic change. By exposing students to dynamic and complex issues from multiple stakeholder perspectives, Changemakers aimed to empower students to find and use their voice and agency to make a difference in society. Students need knowledge and skills to navigate societal challenges, address SDGs and build confidence and creativity to change the status quo (Lozano, 2017; Raelin, 2009). Changemakers provided a playful and safe learning environment to explore societal challenges, form inclusive and sensitive judgments, and enact interventions for change. Students developed self-efficacy (Bandura, 2001) that were encouraged to be autonomous and self-directed in their learning (Morris, 2019). Through learning-by-doing, students gained a set of leadership and change management skills that can be applied to a variety of professional settings in local and global contexts.