Re-structuring of a Dutch mono-industrial region; example of TwenteTable of contents of the chapter Introduction Geography and location of Twente Industrialization of Twente and development of the Textile Industry Decline of the Textile Industry Restructuring Twente: arguments for a regional innovation strategy Moving towards a more diversified economy Stronger co-operation between governments, universities, and industries The role of universities and the example of ‘Kennispark Twente’ Further regional and international co-operation Twente today