How can university and city administration co-create the city? Where do their interests meet and diverge, and what is needed to exploit synergies? This report explores the potential for co-creation in five domains: urban economic development, internationalisation, urban attractiveness & city branding, science & society, and student life. We provide numerous examples from the 10 medium-sized European cities that participated in the EUniverCities project (URBACT). But also we discuss pitfalls and dilemmas. This publication is the final report of the project, synthesizing the main results and findings.