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Products 1.459

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Responsiveness of exercise parameters in children with inflammatory myositis

OBJECTIVE: Juvenile dermatomyositis (DM) is an inflammatory myopathy in which the immune system targets the microvasculature of the skeletal muscle and skin, leading to significant muscle weakness and exercise intolerance, although the precise etiology is unknown. The goal of this study was to investigate the changes in exercise capacity in children with myositis during active and inactive disease periods and to study the responsiveness of exercise parameters.METHODS: Thirteen children with juvenile DM (mean+/-SD age 11.2+/-2.6 years) participated in this study. Patients performed a maximal exercise test using an electronically braked cycle ergometer and respiratory gas analysis system. Exercise parameters were analyzed, including peak oxygen uptake (VO2peak), peak work rate (Wpeak), and ventilatory anaerobic threshold (VAT). All children were tested during an active period of the disease and during a remission period. From these data, 4 different response statistics were calculated.RESULTS: The children performed significantly better during a remission period compared with a period of active disease. Most exercise parameters showed a very large response. The 5 most responsive parameters were Wpeak, Wpeak (percent predicted), oxygen pulse, VO2peak, and power at the VAT.CONCLUSION: We found in our longitudinal study that children with active juvenile DM had significantly reduced exercise parameters compared with a remission period. Moreover, we found that several parameters had very good responsiveness. With previously established validity and reliability, exercise testing has been demonstrated to be an excellent noninvasive instrument for the longitudinal followup of children with myositis.

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Responsiveness of exercise parameters in children with inflammatory myositis

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Exercise capacity in non-specific chronic low back pain patients

OBJECTIVE: Measurement of exercise capacity is essential in patients with non-specific chronic low back pain (CLBP). However, the conventional Astrand bicycle test is not feasible in patients with a very poor aerobic capacity. Therefore the Astrand bicycles test for non-specific CLBP patients based on lean body mass (LBM) was developed as an alternative. The aim of this study was to evaluate reliability and validity of the LBM-based Astrand test.SUBJECTS: Twenty patients with non-specific CLBP and 20 healthy subjects were included for the reliability evaluation, and 19 healthy subjects for the validity evaluation.METHOD: Patients and healthy subjects were assessed twice. Intra class correlation (ICC), repeatability coefficient (RC) and the limits of agreement (LOA) were calculated as a measure of test re-tests reliability. An ICC >or= 0.75 was considered acceptable. Validity was tested by calculating ICC between the LBM-based Astrand test and a maximal bicycle test.RESULTS: The LBM-based Astrand test shows good reliability, reflected by an ICC >or= 0.91 and 95% of the 20 patients could perform the test. However, differences with the estimated true value reflected by the RC and natural variation reflected by the LOA were substantial in patients. Validity was good, reflected by ICC >or= 0.88.CONCLUSION: The present study shows that the LBM-based Astrand test is a reliable, valid, and feasible method for patients with non-specific CLBP. However, a substantial amount of variation should be taken into account in patients when interpreting the test results clinically.

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Effect of training intensity on insulin sensitivity evaluated by insulin tolerance test

This research article shows that a high intensity exercise program compared to a low intensity exercise program of the same session duration and frequency, increases insulin sensitivity to a larger extend in healthy subjects. It also shows that the short insulin tolerance test can be used to detect differences in insulin sensitivity in intervention studies.

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People 1

person

Johan de Jong

Professor

Projects 12

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Erasmus+ sport - Motor Activity Training Program for persons with severe or profound intellectual and multiple disabilities

The central aim of this project is to increase the participation of people (all ages) with severe multiple disabilities (PIMD) in the field of sport, exercise and physical activity, by expanding the number of coaches and organizations who offer a Motor Activity Training Program in a professional and custom way. This aim will be achieved by the following activities:- Creating a more appropriate and varied offer of sport, exercise, and physical activity to increase the choice of the PIMD target group. - To develop a curriculum for MATP Coaches and Trainers (PE Teachers, Physical Therapists, etc). - To implement, test and contextualize a PIMD offer in 3 EU countries, this will be done with local stakeholders. - Strengthening the connection between sport, education and health care organizations to enable participation of the PIMD people in the field of sport, exercise, and physical activity. - Consortium members create a European network and exchange knowledge, including through best practices

Ongoing

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HAN x PWXR x Active Esports Arena

Sinds 2020 voldoen steeds minder Nederlanders aan de beweegrichtlijnen opgesteld door de Gezondheidsraad (van den Berg & Schurink-van ’t Klooster, 2023). Hierbij komt duidelijk naar voren dat vooral jongvolwassenen minder vaak voldoen aan deze richtlijnen (Rijksinstituut voor Volksgezondheid, 2023). Verschillende factoren liggen ten grondslag aan de reden voor vermindering in fysieke activiteit. Een van deze factoren is de toename in sedentaire schermtijd (Benzing & Schmidt, 2018). Deze toename in schermtijd is deels te verklaren door de toename van beeldschermwerk maar ook door de toename van gaming, oftewel het recreatief spelen van videogames door wereldwijd bijna 3,4 miljard mensen (Newzoo, 2023). Het is hierbij interessant om verder te onderzoeken of de motiverende kracht van videogames kan bijdragen aan het stimuleren van positief gedrag, in dit geval meer sporten en positief bewegen (Bogost, 2007). Om dit te kunnen bewerkstelligen is ‘Exergaming’ uitermate geschikt. Het is namelijk een samensmelting van ‘exercise’ en ‘gaming’. Bij deze vorm van gaming is fysieke activiteit essentieel om het spel te kunnen spelen (Gao, Jung, Pope, & Zhang, 2016). Exergaming is een opkomende trend binnen de fitness sector, onderwijs en gezondheidszorg (Benzing & Schmidt, 2018). Het wordt al breed ingezet bij bijvoorbeeld preventie van obesitas(Gao & Chen, 2014), behandeling van Parkinson (Barry, Galna, & Rochester, 2014) maar ook herstel na kanker (Benzing, et al., 2018). Denk hierbij aan populaire games in Virtual Reality. maar ook aan digitale varianten van traditionele sporten gespeeld in Augmented Reality (AR). Naast VR & AR wordt ook gebruik gemaakt van Extended reality (XR) wat een verzameling is van VR, AR & MR (Mixed Reality).Hierin worden alle zintuigen aangesproken waardoor men als het ware ondergedompeld wordt in een ervaring. Men spreekt hier vaak over immersieve technologie. Onze testcase, de Active Esports Arena van het bedrijf: PWXR, is een perfect voorbeeld van zo een ervaring.

Finished

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LIFELINE; eheaLth to InForm Exercise after criticaL IllNEss

HET 'POST INTENSIVE CARE SYNDROOM'; LANGDURIGE GEVOLGEN VAN EEN INTENSIVE CARE OPNAME Dankzij verbeteringen in de zorg overleven steeds meer patiënten de behandeling op een intensive care (IC). Keerzijde hiervan zijn de lichamelijke en mentale klachten (Post Intensive Care Syndroom - PICS) waarvoor patiënten vaak langdurige revalidatie nodig hebben i.v.m. verminderde belastbaarheid en vermoeidheid. Tijdens de Covid-19 pandemie blijkt dat relatief veel IC-patiënten een migratieachtergrond en/of lage sociaaleconomische status hebben en dat een grote groep geen nazorg ontvangt. E-HEALTH ALS ONDERSTEUNING VAN DE ZORGVERLENER: HOE ZET JE HET IN? Om de Juiste Zorg op de Juiste Plek te geven wordt eHealth met coaching en telemonitoring steeds vaker ingezet bij revalidatie in de thuissituatie. Atris is een voorbeeld van een toepassing waarbij via sensoren het activiteitenniveau en hartslag gemeten worden. Atris is een veelbelovende toepassing voor patiënten met PICS maar fysiotherapeuten hebben nog beperkt ervaring met het integreren van eHealth in de behandelaanpak en beschikken over onvoldoende kennis en vaardigheden om de applicaties optimaal in te zetten en zorg op afstand te verlenen. E-HEALTH ALS ONDERSTEUNING VAN DE PATIËNT: JUISTE ZORG OP DE JUISTE PLEK VOOR IEDEREEN? eHealth applicaties dienen de zelfredzaamheid, zelfstandigheid en eigen regie van patiënten te bevorderen. Bij patiënten die thuis herstellen na een IC opname kan eHealth door gebruik van continue monitoring van vitale parameters, patiënten ondersteunen door het gevoel van veiligheid te vergroten en inzicht te verschaffen in belasting en belastbaarheid. Echter, bestaande applicaties zijn momenteel niet voor iedereen toegankelijk zoals mensen met een migratieachtergrond of beperkte gezondheidsvaardigheden. Het doel van het Lifeline project is om, in een consortium met professionals vanuit de technologie, revalidatie en maatschappelijke organisaties, de bestaande Atris applicatie door te ontwikkelen richting een slimme, gebruiksvriendelijke en toegankelijke app en toe te passen in de fysiotherapeutische behandeling van patiënten met PICS.

Finished

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Optimizing nutritional counseling for the disabled athlete

Along with the rapidly growing number of disabled people participating in competitive sports, there is an increased need for (para)medical support in disability sports. Disabled athletes experience differences in body composition, metabolism, training load and habitual activity patterns compared with non-disabled athletes. Moreover, it has been suggested that the well-recognized athlete triad, and low energy availability and low bone mineral density in particular, is even a greater challenge in disabled athletes. Therefore, it is not surprising that sport nutritionists of disabled athletes have expressed an urgency for increased knowledge and insights on the nutritional demands of this group. This project aims to investigate energy expenditure, dietary intake, body composition and bone health of disabled athletes, ultimately leading to nutritional guidelines that promote health and optimal sports performance for this unique population. For this purpose, we will conduct a series of studies and implementation activities that are inter-related and build on the latest insights from sports practice, technology and science. Our international consortium is highly qualified to achieve this goal. It consists of knowledge institutes including world-leading experts in sport and nutrition research, complemented with practical insights from nutritionists working with disabled athletes and the involvement of athletes and teams through the Dutch and Norwegian Olympic committees. The international collaboration, which is a clear strength of this project, is not only focused on research, but also on the optimization of professional practice and educational activities. In this regard, the outcomes of this project will be directly available for practical use by the (para)medical staff working with disabled athletes, and will be extensively communicated to sport teams to ensure that the new insights are directly embedded into daily practice. The project outcomes will also be incorporated in educational activities for dietetics and sport and exercise students, thereby increasing knowledge of future practitioners.

Finished

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Playful Data-driven Active Urban Living (PAUL)

Lack of physical activity in urban contexts is an increasing health risk in The Netherlands and Brazil. Exercise applications (apps) are seen as potential ways of increasing physical activity. However, physical activity apps in app stores commonly lack a scientific base. Consequently, it remains unknown what specific content messages should contain and how messages can be personalized to the individual. Moreover, it is unknown how their effects depend on the physical urban environment in which people live and on personal characteristics and attitudes. The current project aims to get insight in how mobile personalized technology can motivate urban residents to become physically active. More specifically, we aim to gain insight into the effectiveness of elements within an exercise app (motivational feedback, goal setting, individualized messages, gaming elements (gamification) for making people more physically active, and how the effectiveness depends on characteristics of the individual and the urban setting. This results in a flexible exercise app for inactive citizens based on theories in data mining, machine learning, exercise psychology, behavioral change and gamification. The sensors on the mobile phone, together with sensors (beacons) in public spaces, combined with sociodemographic and land use information will generate a massive amount of data. The project involves analysis in two ways. First, a unique feature of our project is that we apply machine learning/data mining techniques to optimize the app specification for each individual in a dynamic and iterative research design (Sequential Multiple Assignment Randomised Trial (SMART)), by testing the effectiveness of specific messages given personal and urban characteristics. Second, the implementation of the app in Sao Paolo and Amsterdam will provide us with (big) data on use of functionalities, physical activity, motivation etc. allowing us to investigate in detail the effects of personalized technology on lifestyle in different geographical and cultural contexts.

Finished

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Playful Data-driven Active Urban Living (PAUL) - SIA

Finished

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RI2020.RAAK.PRO03.043

Finished

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The GALM effect study: changes in physical activity, health and fitness of sedentary and underactive older adults aged 55-65.

Regular physical activity is considered to be an important component of a healthy lifestyle that decreases the risk of coronary heart disease, diabetes mellitus type 2, hypertension, colon and breast cancer, obesity and other debilitating conditions. Physical activity can also improve functional capacity and therefore also the quality of life in older adults. Despite all these favorable aspects, a substantial part of the Dutch older adult population is still underactive or even sedentary. To change this for the better, the Groningen Active Living Model (GALM) was developed.Aim of GALM is to stimulate recreational sports activities in sedentary and underactive older adults in the 55-65 age band. After a door-to-door visit as part of an intensive recruitment phase, a fitness test was conducted followed by the GALM recreational sports program. This program was based on principles from evolutionary-biological play theory and insights fromsocial cognitive theory. The program was versatile in nature (e.g. softball, dance, self-defense, swimming, athletics, etc.) in two main ways: a) to improve compliance with the program different sports were offered, which was reported to be more appealing for older adults; b) by aiming at more components of motor fitness (e.g. strength, flexibility, speed, endurance and coordination). Between 1997 and 2005 more than 552,000 persons were visited door-to-door, over 55,700 were tested, and 41,310 participated in the GALM recreational sports program. The aim of the present thesis is to determine the effects of participation in the GALM recreational sports program on physical activity, health and fitness outcomes.Chapter 2 describes the effectiveness of the GALM recruitment in selecting and recruiting sedentary and underactive older adults. Three municipalities in the Netherlands were selected, and in every municipality four neighborhoods were included. Two of each of the four neighborhoods were randomly assigned as intervention and the others as control neighborhoods. In total, 8,504 persons were mailed and received a home visit. During this home visit the GALM recruitment questionnaire was collected on which the selection between sedentary/underactive and physically active older adults was based. Ultimately we succeeded inincluding 12.3% (315 of the 2,551 qualifying) of the older adults, 79.4% of whom could be indeed considered sedentary or underactive. The cost of successfully recruiting an older adult was estimated at $84.To assess the effects of a physical activity intervention on health and fitness and explain the results, it is necessary to know program characteristics regarding frequency, intensity, time and content of the activities. With respect to the GALM recreational sports activity program, the only unknown characteristic was intensity. Chapter 3 describes the intensity of this program systematically. Using heart rate monitors, data of 97 persons (mean age 60.1 yr) were collected in three municipalities. The mean intensity of all 15 GALM sessions was 73.7% of the predicted maximal heart rate. Six percent of the monitored heart rate time could be classified as light, 33% as moderate and 61% as hard. In summary, the GALM recreational sports program meets the 1998 ACSM recommendations for intensity necessary to improve cardiorespiratory fitness.Chapters 4 and 5 describe the effects of 6 and 12 months of participation in the GALM recreational sports program, and 181 persons were followed over time. Results after 6 months revealed only few significant between-group differences favoring the intervention group (i.e. sleep, diastolic blood pressure, perceived fitness score and grip strength). Changes in energyexpenditure for leisure-time physical activities (EELTPA) showed an increase in both study groups. From 6 to 12 months a decrease in EELTPA occurred in the intervention group and an increase in the control group. The significant positive time effects for the health outcomes (diastolic blood pressure, BMI, percentage of body fat) that were found after 6 months were diminishedfrom 6 to 12 months. However, the energy expenditure for recreational sports activities (EERECSPORT) demonstrated a continuous increase over 12 months. Parallel to this, significant main effects for time were found in performance-based fitness outcomes (i.e. simple reaction time, leg strength, flexibility of hamstrings and lower back, and aerobic endurance). After 12 months only a significant between-group difference for flexibility of the hamstrings andlower back was found, favoring the control group. In conclusion, a short-term increase in EELTPA was found with accompanying improvements in health outcomes that more or less disappeared in 6 to 12 months. In the long term, results showed a continuous increase in EERECSPORT and performance-based fitness. This latter increase is probably a reflection of the significantimprovement over time in EERECSPORT and the fact that recreational sports activities are of a higher intensity.Aerobic endurance is regarded as the most important component of motor fitness that is relevant for older adults to function independently. In Chapter 6, the development in aerobic endurance after 18 months of participation in the GALM recreational sports program was assessed by means of changes in heart rate during fixed submaximal exercise. Since both groups were comparable regarding changes in energy expenditure for physical activity after 6 months and testing confirmed this, both groups were combined and considered as one group. Multilevel analyses were conducted and models for change were developed. A significant decrease in heart rate over time was found at all walking speeds (4, 5, 6 and 7 km/h). The average decrease in heart rate was 5.5, 6.0, 10.0 and 9.0 beats/min for the 4, 5, 6 and 7 km/h walking speeds, respectively. The relative decrease varied from 5.1 to 7.4% relative to average heart rates at baseline. These results illustrate that participation in the GALM recreational sports program has a positive significant effect on aerobic endurance, and that the participants are able to perform at submaximal intensity more easily.Based on the overall results it can be concluded that this study contributes to the field in how to effectively recruit sedentary and underactive older adults and stimulate them to become and stay active in recreational sports activities. As far as we know, this recruitment in combination with the recreational sport program is not only unique but also effective toward increasing performance-based fitness in the long term. Short-term effects were found in other leisure-time activities and health outcomes. To further stimulate other leisure-time and probably health outcomes besides the favorable effects that were already seen, additional interventions that pay more attention to behavioral change in terms of how to integrate other activities besides sports activities are recommended.

Finished

Products 1.459

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Responsiveness of exercise parameters in children with inflammatory myositis

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Exercise capacity in non-specific chronic low back pain patients

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Effect of training intensity on insulin sensitivity evaluated by insulin tolerance test

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