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Background: Different surgical approaches for total hip arthroplasty (THA) exist, without predisposition when it comes to dislocation risk. The direct anterior approach (DAA) is thought to have reduced risk since soft tissue trauma is minimalized. Therefore, we assessed the dislocation risk for different surgical approaches, and the relative dislocation risk of DAA compared to other approaches. Methods: Six electronic databases were systematically searched for prospective studies reporting dislocation following THA. Proportion meta-analyses were performed to assess the dislocation rate for subgroups of the surgical approach. Meta-analysis for binary outcomes was performed to determine the relative risk of dislocation for the DAA compared to other approaches. Results: Eleven studies with 2025 patients were included (mean age 64.6 years, 44% male, mean follow-up 10.5 months), of which four studies were also used in the risk ratio meta-analysis. Overall dislocation rate was 0.79% (95% CI 0.37–1.69). Subgroup analyses showed that most dislocations occurred in the posterior approaches group (1.38%), however non-significant. Furthermore, the DAA emerged with a non-significant lower risk of dislocation (RR 0.37, 95% CI 0.05–2.46) compared to other surgical approaches. Conclusion: Current literature shows non-significant predisposition for a surgical approach to THA regarding dislocation risk. To what extent patient characteristics influence the risk of dislocation could not be determined. Future research should focus on this, as well as on the influence of a surgeon's experience with a specific approach.
Integrating physical therapy sessions and an online application (e-Exercise) might support people with hip osteoarthritis (OA), knee OA, or both (hip/knee OA) in taking an active role in the management of their chronic condition and may reduce the number of physical therapy sessions. The objective of this study was to investigate the short- and long-term effectiveness of e-Exercise compared to usual physical therapy in people with hip/knee OA. The design was a prospective, single-blind, multicenter, superiority, cluster-randomized controlled trial. e-Exercise is a 3-month intervention in which about 5 face-to-face physical therapy sessions were integrated with an online application consisting of graded activity, exercise, and information modules. Usual physical therapy was conducted according to the Dutch physical therapy guidelines on hip and knee OA. Primary outcomes, measured at baseline after 3 and 12 months, were physical functioning and free-living physical activity. Secondary outcome measures were pain, tiredness, quality of life, self-efficacy, and the number of physical therapy sessions.
MUSE supports the CIVITAS Community to increase its impact on urban mobility policy making and advance it to a higher level of knowledge, exchange, and sustainability.As the current Coordination and Support Action for the CIVITAS Initiative, MUSE primarily engages in support activities to boost the impact of CIVITAS Community activities on sustainable urban mobility policy. Its main objectives are to:- Act as a destination for knowledge developed by the CIVITAS Community over the past twenty years.- Expand and strengthen relationships between cities and stakeholders at all levels.- Support the enrichment of the wider urban mobility community by providing learning opportunities.Through these goals, the CIVITAS Initiative strives to support the mobility and transport goals of the European Commission, and in turn those in the European Green Deal.Breda University of Applied Sciences is the task leader of Task 7.3: Exploitation of the Mobility Educational Network and Task 7.4: Mobility Powered by Youth Facilitation.
Aanleiding: De belangstelling voor gezonde en veilige voeding is groot. Bij de gezondheidseffecten van voeding spelen de darmen een cruciale rol. Verschillende soorten bedrijven hebben behoefte aan natuurgetrouwe testmodellen om de effecten van voeding op de darmen te bestuderen. Ze zijn vooral op zoek naar modellen waarvan de uitkomsten direct vertaalbaar zijn naar het doelorganisme (de mens of bijvoorbeeld het varken) en die niet gebruikmaken van kostbare en maatschappelijke beladen dierproeven. Doelstelling Het project 2-REAL-GUTS heeft als doel om twee innovatieve dierproefvrije darmmodellen geschikt te maken voor onderzoek naar voedingsconcepten en -ingrediënten. De twee darmmodellen die worden toegepast zijn darmorganoïden, minidarmorgaantjes bestaande uit stamcellen, en darmexplants bestaande uit hele stukjes darm verkregen uit relevante organismen. Beide modellen hebben potentieel heel uitgebreide toepassingsmogelijkheden en hebben ook grote voordelen ten opzichte van de huidige veelgebruikte cellijnen, omdat ze meerdere in de darm aanwezige celtypen bevatten en uit verschillende specifieke darmregio's te verkrijgen zijn. Gezamenlijk gaan de partners werken aan: 1) het aanpassen van de kweekomstandigheden zodat darmmodellen geschikt worden om de vragen van partners te beantwoorden; 2) het vaststellen van de toepassingsmogelijkheden van de darmmodellen door verschillende stoffen en producten te testen. Beoogde resultaten Kennisconferenties, publicaties en exploitatie van de modellen zullen zorgen voor het verspreiden van de opgedane kennis. Omdat het project gebruikmaakt van moderne, op de toekomst gerichte laboratoriumtechnieken (kweekmethoden met stamcellen en vitaal weefsel, moleculaire analyses en microscopie), leent het zich uitstekend om geïmplementeerd te worden in het hbo-onderwijs. Als spin-off zal het project dan ook voorzien in een specifieke, voor Nederland unieke hbo-minor op het gebied van stamcel- en aanverwante technologie (zoals organ-on-a-chiptechnologie).
Students in Higher Music Education (HME) are not facilitated to develop both their artistic and academic musical competences. Conservatoires (professional education, or ‘HBO’) traditionally foster the development of musical craftsmanship, while university musicology departments (academic education, or ‘WO’) promote broader perspectives on music’s place in society. All the while, music professionals are increasingly required to combine musical and scholarly knowledge. Indeed, musicianship is more than performance, and musicology more than reflection—a robust musical practice requires people who are versed in both domains. It’s time our education mirrors this blended profession. This proposal entails collaborative projects between a conservatory and a university in two cities where musical performance and musicology equally thrive: Amsterdam (Conservatory and University of Amsterdam) and Utrecht (HKU Utrechts Conservatorium and Utrecht University). Each project will pilot a joint program of study, combining existing modules with newly developed ones. The feasibility of joint degrees will be explored: a combined bachelor’s degree in Amsterdam; and a combined master’s degree in Utrecht. The full innovation process will be translated to a transferable infrastructural model. For 125 students it will fuse praxis-based musical knowledge and skills, practice-led research and academic training. Beyond this, the partners will also use the Comenius funds as a springboard for collaboration between the two cities to enrich their respective BA and MA programs. In the end, the programme will diversify the educational possibilities for students of music in the Netherlands, and thereby increase their professional opportunities in today’s job market.
