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Can Smart Charging Balance the Urban Energy Grid?

Smart charging protocols for electric vehicles can help avoid overload and instability in the electrical distribution network and can increase the proportion of locally generated solar energy used for charging. Our results show that the impact of smart charging depends heavily on the technical charging characteristics of the target vehicle.

Exploring Characteristics of Regenerative Business Models through a Delphi-Inspired Approach

Amidst escalating environmental and social challenges, this study explores regenerative business models’ definition and characteristics. While sustainable models have made considerable strides in research, policy, and practice, the advent of regenerative business models offers a progressive leap forward. Regenerative business models aspire to contribute to ecological restoration and societal well-being. The regenerative business model concept is, however, still in its infancy and lacks a comprehensive definition. Our study aims to expand this knowledge, using a Delphi-inspired approach that builds on the knowledge of academic and business experts. Our approach includes three rounds of surveys: an open-ended survey, a survey for rating and ranking the earlier responses of all participants, and a final survey to select key characteristics. We investigate patterns and distinctions among regenerative, regenerative business, and regenerative business models, and analyze their positioning vis-a-vis circular and net-positive models. Findings underscore that organizations adopting regenerative business models focus on planetary health and societal well-being. They generate value across multiple stakeholder levels, including nature, societies, customers, suppliers, shareholders, and employees. Despite overlapping with circular and net-positive models, regenerative business models also emphasize interdependencies between humans and nature, and provide a more holistic approach, centered on restoration rather than mere mitigation.

The cost-effectiveness of the Dutch In Balance fall prevention intervention compared to exercise recommendations among community-dwelling older adults with an increased risk of falls: a randomized controlled trial

The overview effect

Inaugural address of Frederike Praasterink, Professor Future Food Systems 22 February 2018. Three important principles contribute to the transformation of food systems: - Redesign food systems from ‘less bad’ to ‘net positive’ - Reconnect consumers, producers, youth - Revalue food through true cost accounting and new business models

Personalising add-on treatment with inhaled corticosteroids in patients with chronic obstructive pulmonary disease: a benefit-harm modelling study

BACKGROUND: Since the benefit-harm balance of adding inhaled corticosteroids to long-acting β2-agonists (LABA) and long-acting muscarinic antagonists (LAMA) for patients with chronic obstructive pulmonary disease is unclear, we evaluated this addition for a range of patient profiles. METHODS: Analyses considered the effects of low-to-moderate doses of inhaled corticosteroids, LABA, and LAMA compared with LABA and LAMA alone, outcome incidences, and preference weights assigned to averted moderate-to-severe exacerbations (benefit) and severe pneumonia, candidiasis, and dysphonia (harm). Using exponential models, we estimated the preference weight-adjusted 2-year net clinical benefit (ie, benefits outweighing harms) indices. Exacerbation risk thresholds for triggering inhaled corticosteroids, LABA, and LAMA were established when the probability of a 2-year net clinical benefit reached 60%. We estimated the proportion of patients benefiting from added inhaled corticosteroids using an externally validated prediction model for acute exacerbations in primary care. FINDINGS: Adding low-to-moderate dose inhaled corticosteroids to LABA and LAMA provided a net clinical benefit in patients with a 2-year baseline exacerbation risk of 54-83%. Low-dose inhaled corticosteroids showed a net clinical benefit if the baseline risk was 40-91%, but not at higher doses. The benefit was modified by blood eosinophil count (BEC) and age. Although no net benefit was associated with a BEC of less than 150 cells per μL, patients with a BEC of 150 cells per μL or more had a net benefit from low-dose inhaled corticosteroids with a 2-year exacerbation risk of 32-95% in those aged 40-79 years and 41-93% in those older than 80 years. A moderate dose of inhaled corticosteroids showed a net benefit in patients younger than 80 years with a BEC of 150 cells per μL or more at 52-86% 2-year exacerbation risk. Depending on the subgroups, the proportion of patients with a net benefit from added inhaled corticosteroids ranged from 0 to 68%. INTERPRETATION: The net clinical benefit of adding different inhaled corticosteroid doses to LABA and LAMA varies greatly with exacerbation risk, BEC, and age. Personalised treatment decisions based on these factors and predicted exacerbation risks might reduce overtreatment and undertreatment with inhaled corticosteroids.None.

Towards a carbon credit & blue credit scheme for peatlands

The aim of this document is to outline the preliminary requirements and steps needed to fully establish frameworks for certification systems across Europe, specifically to support and incentivize the restoration of peatlands and to provide a framework for reducing GHG emissions from degraded and mismanaged peatlands on a large scale. This will ensure that peatlands across Europe fulfil their potential to become a net carbon sink by 2050, while optimizing ecosystem service provision in a way that is fully consistent with all the relevant European policies. This report covers the following topics: - Analysis of current Carbon Credit systems and other incentives to support wet peatlands. - Economic land use analysis relating to peatlands. - Outline of a framework to support rewetting and peatland restoration. - Recommendations for an Eco-Credit system across Europe.