Phantom limb pain following amputation is highly prevalent as it affects up to 80% of amputees. Many amputees suffer from phantom limb pain for many years and experience major limitations in daily routines and quality of life. Conventional pharmacological interventions often have negative side-effects and evidence regarding their long-term efficacy is low. Central malplasticity such as the invasion of areas neighbouring the cortical representation of the amputated limb contributes to the occurrence and maintenance of phantom limb pain. In this context, alternative, non-pharmacological interventions such as mirror therapy that are thought to target these central mechanisms have gained increasing attention in the treatment of phantom limb pain. However, a standardized evidence-based treatment protocol for mirror therapy in patients with phantom limb pain is lacking, and evidence for its effectiveness is still low. Furthermore, given the chronic nature of phantom limb pain and suggested central malplasticity, published studies proposed that patients should self-deliver mirror therapy over several weeks to months to achieve sustainable effects. To achieve this training intensity, patients need to perform self-delivered exercises on a regular basis, which could be facilitated though the use of information and communication technology such as telerehabilitation. However, little is known about potential benefits of using telerehabilitation in patients with phantom limb pain, and controlled clinical trials investigating effects are lacking. The present thesis presents the findings from the ‘PAtient Centered Telerehabilitation’ (PACT) project, which was conducted in three consecutive phases: 1) creating a theoretical foundation; 2) modelling the intervention; and 3) evaluating the intervention in clinical practice. The objectives formulated for the three phases of the PACT project were: 1) to conduct a systematic review of the literature regarding important clinical aspects of mirror therapy. It focused on the evidence of applying mirror therapy in patients with stroke, complex regional pain syndrome and phantom limb pain. 2) to design and develop a clinical framework and a user-centred telerehabilitation for mirror therapy in patients with phantom limb pain following lower limb amputation. 3) to evaluate the effects of the clinical framework for mirror therapy and the additional effects of the teletreatment in patients with phantom limb pain. It also investigated whether the interventions were delivered by patients and therapists as intended.
BACKGROUND: The Quebec Back Pain Disability Scale (QBPDS) has been translated into different languages, and several studies on its measurement properties have been done. PURPOSE: The purpose of this review was to critically appraise and compare the measurement properties, when possible, of all language versions of the QBPDS by systematically reviewing the methodological quality and results of the available studies. METHOD: Bibliographic databases (PubMed, Embase, CINAHL, and PsycINFO) were searched for articles with the key words "Quebec," "back," "pain," and "disability" in combination with a methodological search filter for finding studies on measurement properties concerning the development or evaluation of the measurement properties of the QBPDS in patients with nonspecific low back pain. Assessment of the methodological quality was carried out by the reviewers using the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist for both the original language version of the QBPDS in English and French and all translated versions. The results of the measurement properties were rated based on criteria proposed by Terwee et al. RESULTS: The search strategy resulted in identification of 1,436 publications, and 27 articles were included in the systematic review. There was limited-to-moderate evidence of good reliability, validity, and responsiveness of the QBPDS for the different language versions, but for no language version was evidence available for all measurement properties. CONCLUSION: For research and clinical practice, caution is advised when using the QBPDS to measure disability in patients with nonspecific low back pain. Strong evidence is lacking on all measurement properties for each language version of the QBPDS.
Studies about clinical pain in schizophrenia are rare. Conclusions on pain sensitivity in people with schizophrenia are primarily based on experimental pain studies. This review attempts to assess clinical pain, that is, everyday pain without experimental manipulation, in people with schizophrenia. PubMed, PsycINFO, Embase.com, and Cochrane were searched with terms related to schizophrenia and pain. Methodological quality was assessed with the Mixed Methods Appraisal Tool. Fourteen studies were included. Persons with schizophrenia appear to have a diminished prevalence of pain, as well as a lower intensity of pain when compared to persons with other psychiatric diseases. When compared to healthy controls, both prevalence and intensity of pain appear to be diminished for persons with schizophrenia. However, it was found that this effect only applies to pain with an apparent medical cause, such as headache after lumbar puncture. For less severe situations, prevalence and intensity of pain appears to be comparable between people with schizophrenia and controls. Possible underlying mechanisms are discussed. Knowledge about pain in schizophrenia is important for adequate pain treatment in clinical practice. Perspective This review presents a valuable insight into clinical pain in people with schizophrenia
Even though considerable amounts of valuable wood are collected at waste collection sites, most of it remains unused and is burned: it is too labor-intensive to sort, process and upcycle useable parts. Valuable wood thus becomes worthless waste, against circular economy principles. In MoBot-Wood, waste collection organizations HVC and the municipality of Amsterdam, together with Rolan Robotics, Metabolic and AUAS investigate how waste wood can be sorted and processed at waste collection sites, using an easy-to-deploy robotic solution. In various preceding and on-going projects, AUAS and partners are exploring circular wood intake, sorting and processing using industrial robots, including processes like machine vision, 3D scanning, sawing, and milling. These projects show that harvesting waste wood is a challenging matter. Generally, the wood is only partially useable due to the presence of metal, excessive paint, deterioration by fungi and water, or other contamination and damages. To harvest useable wood thus requires intensive sorting and processing. The solution of transporting all the waste wood from collection sites to a central processing station might be too expensive and have a negative environmental impact. Considering that much of collected wood will need to be discarded, often no wood is harvested at all, due to the costs for collection and shipping. Speaking with several partners in related projects, the idea emerged to develop a mobile robotic station, which can be (temporarily) deployed at waste collection sites, to intake, sort and process wood for upcycling. In MoBot-Wood, research entails the design of such station, its deployment conditions, and a general assessment of its potential impact. The project investigates robotic sorting and processing on location as a new approach to increase the amount of valuable, useable wood harvested at waste collection sites, by avoiding material transport and reducing the volume of remaining waste.
Niet specifieke nekpijn (NSNP) vormt een groot probleem binnen de volwassen westerse bevolking. Deze aandoening is complex, invaliderend en kent een heterogene presentatie, waardoor NSNP moeilijk te behandelen is. Een brede beoordeling van de (complexe) klacht waarbij medische en psychosociale prognostische factoren een centrale rol spelen is essentieel om te kunnen beoordelen welke zorg het meest passend is. Dit verhoogd de doelmatigheid van zorg en verminderd de kans op onnodige zorg. Meer inzicht in heterogene patiëntengroepen door het bepalen van verschillende fenotypen kan nuttig zijn bij het ontwikkelen van gerichte interventies om het behandelresultaat te verbeteren. Psychologische en sociale factoren spelen een belangrijke rol bij het in standhouden van de ervaren pijn. De nieuwste wetenschappelijke inzichten en praktijkrichtlijnen adviseren dan ook met nadruk een biopsychosociale benadering bij patiënten met NSNP. Hoewel fysiotherapeuten hierin geschoold worden, ervaren zij nog wel regelmatig ongemak en uitdagingen bij het integreren van psychologische en sociale factoren in de diagnostiek en behandeling van deze patiëntengroep. Daarom rijst de vraag uit het werkveld: Hoe kunnen fysiotherapeuten in de eerstelijn beter in staat gesteld worden om bij mensen met nekpijn de complexiteit van de klachten in te schatten en behandelingen op maat aan te bieden en waar nodig samen te werken met een gespecialiseerde fysiotherapeut? Of is een andere discipline in de eerstelijnszorg noodzakelijk om multidisciplinair mee samen te werken? Om deze vraag te beantwoorden hebben wij een breed consortium samengesteld uit eerdere en nieuwe (MKB) partners. Het doel van dit onderzoek is om fysiotherapeuten handvatten te bieden voor het op maat (gepersonaliseerd) behandelen van patiënten met NSNP. Het onderzoek bestaat uit drie delen; (1)het fenotyperen op het gebied van psychosociale factoren in patiënten met (sub)acute NSNP, (2)het maken van een screeningstool om de fenotypen te identificeren en (3)het evalueren van een passende behandeling bij de verschillende fenotypen.
