Fingerprints are widely used in forensic science for individualization purposes. However, not every fingermark found at a crime scene is suitable for comparison, for instance due to distortion of ridge detail, or when the reference fingerprint is not in the database. To still retrieve information from these fingermarks, several studies have been initiated into the chemical composition of fingermarks, which is believed to be influenced by several donor traits. Yet, it is still unclear what donor information can be retrieved from the composition of one's fingerprint, mainly because of limited sample sizes and the focus on analytical method development. It this paper, we analyzed the chemical composition of 1852 fingerprints, donated by 463 donors during the Dutch music festival Lowlands in 2016. In a targeted approach we compared amino acid and lipid profiles obtained from different types of fingerprints. We found a large inter-variability in both amino acid and lipid content, and significant differences in L-(iso)leucine, L-phenylalanine and palmitoleic acid levels between male and female donors. In an untargeted approach we used full-scan MS data to generate classification models to predict gender (77.9% accuracy) and smoking habit (90.4% accuracy) of fingerprint donors. In the latter, putatively, nicotine and cotinine are used as predictors.
MULTIFILE
There are lots of definitions of quality, and also of quality in education. Garvin (1984)discerns five approaches: the transcendental approach, the product-oriented approach, the customeroriented approach, the manufacturing-oriented approach and the value-for-money approach. Harvey and Green (1993) give five interrelated concepts of quality as: exceptional, perfection (or consistency), fitness for purpose, value for money and transformative. A new definition of quality is needed to explain recent quality issues in higher education. This article describes a quality concept with four constituents: object, standard, subject and values. The article elaborates on the values. Four value systems derived from Beck and Cowan (1996) are transformed into four value systems on quality and quality management: control, continuous improvement, commitment and breakthrough. These value systems make it possible to explain some recent developments in quality management in higher education.
Author Supplied: In the last decades, architecture has emerged as a discipline in the domain of Information Technology (IT). A well-accepted definition of architecture is from ISO/IEC 42010: "The fundamental organization of a system, embodied in its components, their relationships to each other and the environment, and the principles governing its design and evolution." Currently, many levels and types of architecture in the domain of IT have been defined. We have scoped our work to two types of architecture: enterprise architecture and software architecture. IT architecture work is demanding and challenging and includes, inter alia, identifying architectural significant requirements (functional and non-functional), designing and selecting solutions for these requirements, and ensuring that the solutions are implemented according to the architectural design. To reflect on the quality of architecture work, we have taken ISO/IEC 8402 as a starting point. It defines quality as "the totality of characteristics of an entity that bear on its ability to satisfy stated requirements". We consider architecture work to be of high quality, when it is effective; when it answers stated requirements. Although IT Architecture has been introduced in many organizations, the elaboration does not always proceed without problems. In the domain of enterprise architecture, most practices are still in the early stages of maturity with, for example, low scores on the focus areas ‘Development of architecture’ and ‘Monitoring’ (of the implementation activities). In the domain of software architecture, problems of the same kind are observed. For instance, architecture designs are frequently poor and incomplete, while architecture compliance checking is performed in practice on a limited scale only. With our work, we intend to contribute to the advancement of architecture in the domain of IT and the effectiveness of architecture work by means of the development and improvement of supporting instruments and tools. In line with this intention, the main research question of this thesis is: How can the effectiveness of IT architecture work be evaluated and improved?
Veel van de isolatiematerialen die we momenteel gebruiken, zoals glaswol en steenwol, hebben een behoorlijke impact op het milieu en zijn niet circulair. Gelukkig zijn er alternatieven die beter zijn voor de natuur, zoals isolatie gemaakt van biobased materialen zoals houtvezels en hennepvezels. Deze materialen zijn hernieuwbaar en hebben vrijwel geen nadelige effecten op het milieu, zijn gunstig voor een gezond binnenklimaat in een woning, terwijl ze nog steeds goede isolerende eigenschappen hebben. De ambitie van de rijksoverheid is dat in 2030 minstens 30% van de nieuwbouwwoningen uit minimaal 30% van deze biobased materialen bestaan. Hetzelfde percentage geldt als doelstelling voor isolatiemaatregelen voor verduurzaming en voor de gebruikte materialen voor utiliteitsbouw. Een nieuwe ontwikkeling is het gebruik van mycelium, schimmels die zorgen voor de groei van een materiaal wat ingezet kan worden als isolatie. Mycelium heeft isolerende en akoestische eigenschappen, is waterafstotend en brandwerend. Mycelium panelen op de huidige markt worden belemmerd in hun ontwikkeling doordat ze in mallen worden gegroeid, hierdoor kunnen er geen grotere diktes bereikt worden in verband met de benodigde groeiomstandigheden van mycelium. Dit leidt tot verminderde isolerende eigenschappen. Door geavanceerde 3D-printtechnieken te gebruiken waarbij er complexe vormen geprint kunnen worden die de groei van mycelium bevorderen ook op grotere diktes, willen we in dit 1-jarige KIEM project onderzoeken hoe we een innovatief mycelium isolatiemateriaal kunnen ontwikkelen, geschikt voor 3D printers, dat nog beter past bij de behoeften vanuit de markt. De resultaten van deze studie kunnen aantonen dat de toepassing van biobased isolatiematerialen en geavanceerde productiemethoden niet alleen leiden tot een efficiëntere isolatie van gebouwen, maar ook de milieueffecten vermindert en nieuwe mogelijkheden biedt voor diverse en grootschalige toepassingen.
In the context of global efforts to increase sustainability and reduce CO2 emissions in the chemical industry, bio-based materials are receiving increasing attention as renewable alternatives to petroleum-based polymers. In this regard, Visolis has developed a bio-based platform centered around the efficient conversion of plant-derived sugars to mevalonolactone (MVL) via microbial fermentation. Subsequently, MVL is thermochemically converted to bio-monomers such as isoprene and 3-methyl-1,5-pentane diol, which are ultimately used in the production of polymer materials. Currently, the Visolis process has been optimized to use high-purity, industrial dextrose (glucose) as feedstock for their fermentation process. Dutch Sustainable Development (DSD) has developed a direct processing technology in which sugar beets are used for fermentation without first having to go through sugar extraction and refinery. The main exponent of this technology is their patented Betaprocess, in which the sugar beet is essentially exposed to heat and a mild vacuum explosion, opening the cell walls and releasing the sugar content. This Betaprocess has the potential to speed up current fermentation processes and lower feedstock-related costs. The aim of this project is to combine aforementioned technologies to enable the production of mevalonolactone using sucrose, present in crude sugar beet bray after Betaprocessing. To this end, Zuyd University of Applied Sciences (Zuyd) intends to collaborate with Visolis and DSD. Zuyd will utilize its experience in both (bio)chemical engineering and fermentation to optimize the process from sugar beet (pre)treatment to product recovery. Visolis and DSD will contribute their expertise in microbial engineering and low-cost sugar production. During this collaboration, students and professionals will work together at the Chemelot Innovation and Learning Labs (CHILL) on the Brightlands campus in Geleen. This collaboration will not only stimulate innovation and sustainable chemistry, but also provides starting professionals with valuable experience in this expanding field.
Studenten in het beroepsonderwijs leren op de werkplek om een goede beroepsuitoefenaar te worden. Beoordeling van het werkplekleren gebeurt vaak op de werkplek en door de werkplek. Dit promotieonderzoek wil in kaart brengen hoe werkplekopleiders de student beoordelen.
