Design and development practitioners such as those in game development often have difficulty comprehending and adhering to the European General Data Protection Regulation (GDPR), especially when designing in a private sensitive way. Inadequate understanding of how to apply the GDPR in the game development process can lead to one of two consequences: 1. inadvertently violating the GDPR with sizeable fines as potential penalties; or 2. avoiding the use of user data entirely. In this paper, we present our work on designing and evaluating the “GDPR Pitstop tool”, a gamified questionnaire developed to empower game developers and designers to increase legal awareness of GDPR laws in a relatable and accessible manner. The GDPR Pitstop tool was developed with a user-centered approach and in close contact with stakeholders, including practitioners from game development, legal experts and communication and design experts. Three design choices worked for this target group: 1. Careful crafting of the language of the questions; 2. a flexible structure; and 3. a playful design. By combining these three elements into the GDPR Pitstop tool, GDPR awareness within the gaming industry can be improved upon and game developers and designers can be empowered to use user data in a GDPR compliant manner. Additionally, this approach can be scaled to confront other tricky issues faced by design professionals such as privacy by design.
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Knowledge of child development influences parental expectations of, and interactions with, children. Studies have shown that maternal knowledge supports cognitive and social–emotional development of young children and can have long-lasting benefits. Level of developmental knowledge of parents and grandparents has seldom been investigated on a population level. Our aim was to compare Canadian and Dutch samples of urban parents and grandparents in terms of normative knowledge of children’s cognitive and social–emotional development. Urban parents (n = 379) and grandparents (n = 174) from the province of Alberta, Canada (N = 553) and parents (n = 634) and grandparents (n = 96) of the city of The Hague in the Netherlands (N = 730) answered questions related to knowledge of cognitive and social–emotional development of young children, including topics such as “do children have stronger bonds with parents who stay at home instead of working outside the home?” and “do children learn more from hearing someone in the same room talk than hearing someone on TV?” Overall, the Canadian respondents were more likely to answer these questions correctly. In both samples, women were more likely than men to answer correctly. No significant relationship between age or role (parent or grandparent) and knowledge was identified, but there was a positive correlation between knowledge and level of education. Little is known about international differences in caregivers’ knowledge about normative child development. This study suggests that differences exist. Understanding differences between countries in parental knowledge may provide insight into cross-cultural variability in child behavioral and developmental outcomes. https://doi.org/10.1177/2158244018777027
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Let op het is Open Access maar met speciale Elsevier user rights, zie https://www.elsevier.com/about/policies/open-access-licenses/elsevier-user-license Background The presence of a comorbid borderline personality disorder (BPD) may be associated with an increase of suicidal behaviors in patients with depressive and anxiety disorders. The aim of this study is to examine the role of borderline personality traits on recurrent suicide attempts. Methods The Netherlands Study on Depression and Anxiety included 1838 respondents with lifetime depressive and/or anxiety disorders, of whom 309 reported at least one previous suicide attempt. A univariable negative binomial regression analysis was performed to examine the association between comorbid borderline personality traits and suicide attempts. Univariable and multivariable negative binomial regression analyses were performed to identify risk factors for the number of recurrent suicide attempts in four clusters (type and severity of axis-I disorders, BPD traits, determinants of suicide attempts and socio-demographics). Results In the total sample the suicide attempt rate ratio increased with 33% for every unit increase in BPD traits. A lifetime diagnosis of dysthymia and comorbid BPD traits, especially the symptoms anger and fights, were independently and significantly associated with recurrent suicide attempts in the final model (n=309). Limitations The screening of personality disorders was added to the NESDA assessments at the 4-year follow-up for the first time. Therefore we were not able to examine the influence of comorbid BPD traits on suicide attempts over time. Conclusions Persons with a lifetime diagnosis of dysthymia combined with borderline personality traits especially difficulties in coping with anger seemed to be at high risk for recurrent suicide attempts. For clinical practice, it is recommended to screen for comorbid borderline personality traits and to strengthen the patient's coping skills with regard to anger.
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Digital transformation has been recognized for its potential to contribute to sustainability goals. It requires companies to develop their Data Analytic Capability (DAC), defined as their ability to collect, manage and analyze data effectively. Despite the governmental efforts to promote digitalization, there seems to be a knowledge gap on how to proceed, with 37% of Dutch SMEs reporting a lack of knowledge, and 33% reporting a lack of support in developing DAC. Participants in the interviews that we organized preparing this proposal indicated a need for guidance on how to develop DAC within their organization given their unique context (e.g. age and experience of the workforce, presence of legacy systems, high daily workload, lack of knowledge of digitalization). While a lot of attention has been given to the technological aspects of DAC, the people, process, and organizational culture aspects are as important, requiring a comprehensive approach and thus a bundling of knowledge from different expertise. Therefore, the objective of this KIEM proposal is to identify organizational enablers and inhibitors of DAC through a series of interviews and case studies, and use these to formulate a preliminary roadmap to DAC. From a structure perspective, the objective of the KIEM proposal will be to explore and solidify the partnership between Breda University of Applied Sciences (BUas), Avans University of Applied Sciences (Avans), Logistics Community Brabant (LCB), van Berkel Logistics BV, Smink Group BV, and iValueImprovement BV. This partnership will be used to develop the preliminary roadmap and pre-test it using action methodology. The action research protocol and preliminary roadmap thereby developed in this KIEM project will form the basis for a subsequent RAAK proposal.
Lupineschillen (lupine zaadhuid) zijn een reststroom van lupineverwerking. Lupineschillen vormen 25% van de totale biomassa van de lupineboon, terwijl sojaschillen slechts 5% van de totale biomassa van de sojaboon zijn. Er zijn onvoldoende rendabele toepassingen voor lupineschillen waardoor de rentabiliteit van de lupine supply chain achter blijft bij de veel competitievere soja supply chain. Lupineschillen zijn rijk aan de actieve stof lupeol waarvan recent farmaceutische en cosmetische anti-aging werkingen zijn vastgesteld, waaronder anti-tumor werking. Lupeol komt naast lupine ook in hoge concentraties voor in berkenbast. Berkenbast bevat bovendien een chemische voorloper van lupeol namelijk betuline. Recentelijk is er een chemische syntheseroute ontwikkeld voor lupeol op basis van betuline. Als deze syntheseroute kosteneffectief is, dan kan deze route de ontwikkeling van nieuwe toepassingen van lupineschillen blokkeren.Het doel van deze studie is het opstellen van een circulair ontwerp voor lupeol extractie uit twee reststromen met behulp van superkritische CO2 extractie en de kosteneffectiviteit van deze circulaire ontwerpen met elkaar vergelijken voor het selecteren van het meest optimale proces voor lupeol extractie en/of synthese. Bovendien worden mogelijke cosmetische anti-aging effecten van lupeol getest.Met behulp van superkritische CO2 extractie is het mogelijk om lupeol kosteneffectief uit lupineschillen te extraheren. De alternatieve syntheseroute van lupeol uit betuline zoals deze in de wetenschappelijke literatuur was gepubliceerd bleek niet reproduceerbaar te zijn. Patentliteratuur leverde een reproduceerbare syntheseroute. Vergelijking van de twee routes was nog niet mogelijk vanwege de lage omzetting efficiënties van de syntheseroute. Daarnaast zijn er mogelijke intellectuele eigendom issues. De effectiviteit van lupeol is in vitro en in vivo getest. Hieruit bleek dat lupeol in tegenstelling tot de literatuur minimale effecten had op huidcellen. De huidelasticiteit bij proefpersonen nam enigszins toe na gebruik van een cosmetische formulering met lupeol.Uit onze studie is gebleken dat we kosteneffectief lupeol kunnen extraheren met behulp van superkritische CO2, dat de alternatieve routes voor lupeol synthese nog niet mogelijk zijn en dat we enige anti-aging effecten van lupeol hebben kunnen vinden bij toepassing in cosmetische producten.
Lupineschillen (lupine zaadhuid) zijn een reststroom van lupineverwerking. Lupineschillen vormen 25% van de totale biomassa van de lupineboon, terwijl sojaschillen slechts 5% van de totale biomassa van de sojaboon zijn. Er zijn onvoldoende rendabele toepassingen voor lupineschillen waardoor de rentabiliteit van de lupine supply chain achter blijft bij de veel competitievere soja supply chain. Lupineschillen zijn rijk aan de botanisch actieve stof lupeol waarvan recent farmaceutische en cosmetische anti-aging werkingen zijn vastgesteld, waaronder anti-tumor werking. Lupeol komt naast lupine ook in hoge concentraties voor in berkenbast. Berkenbast bevat bovendien een chemische voorloper van lupeol namelijk betuline. Recentelijk is er een chemische synthese route ontwikkeld voor lupeol op basis van betuline. Als deze synthese route kosten effectief is, dan kan deze route de ontwikkeling van nieuwe toepassingen van lupineschillen blokkeren. Het doel van deze studie is het opstellen van een circulair ontwerp voor lupeol extractie uit twee reststromen met behulp van superkritische CO2 extractie en de kosteneffectiviteit van deze circulaire ontwerpen met elkaar vergelijken voor het selecteren van het meest optimale proces voor lupeol extractie en/of synthese. Daarnaast worden effecten van verschillende lupeol extracten (lupineschil en berkenbast) met in-vitro testen vastgesteld en met elkaar vergeleken.
