Background: Although research on children's motor competence is a growing field of interest, especially among young children (4-6 years), several questions remain to be answered. Differences in children’s motor competence and their determinants, must be made transparent since early childhood is a critical period for the development of fundamental movement skills, and thereby a lifelong active lifestyle and health. Objective: The purpose of this cross-sectional study was to determine differences in actual motor competence (AMC), perceived motor competence (PMC) and enjoyment of physical activity among young children with different weight status. Methods: AMC, PMC and enjoyment were measured among 1708 children (50.4% male, mean age: 5.34 ± 0.73 years) from 36 primary schools in The Netherlands. AMC was measured by using the Athletic Skills Track (AST-1). The Pictorial Scale of Perceived Movement Skill Competence for Young Children was used for determining PMC and enjoyment of physical activity was measured using a Visual Analogue Scale. The data were analyzed using a three-way ANOVA to examine the differences between AMC, PMC and enjoyment by sex (boys/girls), age (4, 5, 6 years) and weight status (normal, overweight, obesity). Results: Overall, AMC was ranked as ‘average motor gifted’. Average PMC and enjoyment scores were 3.31 (SE 0.01) (1-4 scale) and 4.41 (SE 0.02) (1-5 scale) respectively. No interaction effects were found between sex, age and weight status on AMC or PMC. However, there was a statistically significant two-way interaction effect for enjoyment between age and weight status (F (4,1454) =2.464, p =.043). Relative enjoyment scores for normal weight and overweight groups between high and low enjoyment were distributed 99% to 1%. However, in the obese group there was a distribution of 92% to 8% between high and low enjoyment. Conclusions: The results of this study suggest that there are no significant differences in AMC and PMC between children of different sex, ages (4, 5 and 6 years), and weight status in this age group. However, children with obesity more often experience less enjoyment during physical activity than children with another weight status. Targeted intervention for increasing enjoyment during physical activity in combination with reducing obesity seems advisable even at young age.
Om inzicht te krijgen in spierveroudering is genexpressie gemeten in vastus lateralis biopten van jonge en oude mannen en vrouwen. We vonden dat tijdens het ouder worden bij beide geslachten dezelfde categorieën genen in spieren worden aan- en uitgeschakeld (“gereguleerd”); de mate van deze zogenaamde differentiële expressie was echter geslachtsspecifiek. Bij mannen was oxidatieve fosforylering het meest in het oog springende proces, en bij vrouwen was dit celgroei gemedieerd door AKT-signalering. De conclusie is dat dezelfde processen zijn geassocieerd met skeletspierveroudering bij mannen en vrouwen, maar dat de differentiële expressie van die processen geslachtsspecifiek is.
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Circulating sex hormone levels have been linked to a wide range of cardiovascular risk factors in men, but studies on incident CVD have been inconclusive [1]. Recent data from meta-analyses show an increase in CVD risk with low testosterone in elderly men and no association with estradiol levels [2,3]. To clarify the role of sex hormones in male CVD risk, we examined the cross-sectional and longitudinal associations between endogenous sex hormones and subclinical atherosclerosis in a population-based cohort of middle-aged and older men.
