Deze presentatie is ontwikkeld op verzoek van Delphy voor een workshop tijdens de landelijke informatiebijeenkomst pioenroos. In deze presentatie schets ik op basis van literatuuronderzoek een beeld van de problemen met Phytophthora cactorum in de pioenrozenteelt. Na een kort historisch overzicht worden de kenmerken en omstandigheden van deze oömyceet toegelicht. Vervolgens worden de levenswijze en de symptomen toegelicht en de mogelijkheid om zede ziekten met andere problemen te verwarren. Aan het eind van de presentatie verken ik de mogelijkheden om via een weerbaar teeltsysteem de problemen emt Phytophthora te verminderen.
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Aim: The aim of this study was to describe the experience with commercially available activity trackers embedded in the physiotherapy treatment of patients with a chronic disease. Methods: In a qualitative study, 29 participants with a chronic disease participated. They wore an activity tracker for two to eight weeks. Data were collected using 23 interviews and discussion with 6 participants. A framework analysis was used to analyze the data. Results: The framework analysis resulted in seven categories: purchase, instruction, characteristics, correct functioning, sharing data, privacy, use, and interest in feedback. The standard goal of the activity trackers was experienced as too high, however the tracker still motivated them to be more active. Participants would have liked more guidance from their physiotherapists because they experienced the trackers as complex. Participants experienced some technical failures, are willing to share data with their physiotherapist and, want to spend a maximum of e50,-. Conclusion: The developed framework gives insight into all important concepts from the experiences reported by patients with a chronic disease and can be used to guide further research and practice. Patients with a chronic disease were positive regarding activity trackers in general. When embedded in physiotherapy, more attention should be paid to the integration in treatment.
Aim: The aim of this study was to describe the experience with commercially available activity trackers embedded in the physiotherapy treatment of patients with a chronic disease. Methods: In a qualitative study, 29 participants with a chronic disease participated. They wore an activity tracker for two to eight weeks. Data were collected using 23 interviews and discussion with 6 participants. A framework analysis was used to analyze the data. Results: The framework analysis resulted in seven categories: purchase, instruction, characteristics, correct functioning, sharing data, privacy, use, and interest in feedback. The standard goal of the activity trackers was experienced as too high, however the tracker still motivated them to be more active. Participants would have liked more guidance from their physiotherapists because they experienced the trackers as complex. Participants experienced some technical failures, are willing to share data with their physiotherapist and, want to spend a maximum of €50,-. Conclusion: The developed framework gives insight into all important concepts from the experiences reported by patients with a chronic disease and can be used to guide further research and practice. Patients with a chronic disease were positive regarding activity trackers in general. When embedded in physiotherapy, more attention should be paid to the integration in treatment.
Aanleiding: De belangstelling voor gezonde en veilige voeding is groot. Bij de gezondheidseffecten van voeding spelen de darmen een cruciale rol. Verschillende soorten bedrijven hebben behoefte aan natuurgetrouwe testmodellen om de effecten van voeding op de darmen te bestuderen. Ze zijn vooral op zoek naar modellen waarvan de uitkomsten direct vertaalbaar zijn naar het doelorganisme (de mens of bijvoorbeeld het varken) en die niet gebruikmaken van kostbare en maatschappelijke beladen dierproeven. Doelstelling Het project 2-REAL-GUTS heeft als doel om twee innovatieve dierproefvrije darmmodellen geschikt te maken voor onderzoek naar voedingsconcepten en -ingrediënten. De twee darmmodellen die worden toegepast zijn darmorganoïden, minidarmorgaantjes bestaande uit stamcellen, en darmexplants bestaande uit hele stukjes darm verkregen uit relevante organismen. Beide modellen hebben potentieel heel uitgebreide toepassingsmogelijkheden en hebben ook grote voordelen ten opzichte van de huidige veelgebruikte cellijnen, omdat ze meerdere in de darm aanwezige celtypen bevatten en uit verschillende specifieke darmregio's te verkrijgen zijn. Gezamenlijk gaan de partners werken aan: 1) het aanpassen van de kweekomstandigheden zodat darmmodellen geschikt worden om de vragen van partners te beantwoorden; 2) het vaststellen van de toepassingsmogelijkheden van de darmmodellen door verschillende stoffen en producten te testen. Beoogde resultaten Kennisconferenties, publicaties en exploitatie van de modellen zullen zorgen voor het verspreiden van de opgedane kennis. Omdat het project gebruikmaakt van moderne, op de toekomst gerichte laboratoriumtechnieken (kweekmethoden met stamcellen en vitaal weefsel, moleculaire analyses en microscopie), leent het zich uitstekend om geïmplementeerd te worden in het hbo-onderwijs. Als spin-off zal het project dan ook voorzien in een specifieke, voor Nederland unieke hbo-minor op het gebied van stamcel- en aanverwante technologie (zoals organ-on-a-chiptechnologie).
Micro and macro algae are a rich source of lipids, proteins and carbohydrates, but also of secondary metabolites like phytosterols. Phytosterols have important health effects such as prevention of cardiovascular diseases. Global phytosterol market size was estimated at USD 709.7 million in 2019 and is expected to grow with a CAGR of 8.7% until 2027. Growing adoption of healthy lifestyle has bolstered demand for nutraceutical products. This is expected to be a major factor driving demand for phytosterols. Residues from algae are found in algae farming and processing, are found as beachings and are pruning residues from underwater Giant Kelp forests. Large amounts of brown seaweed beaches in the province of Zeeland and are discarded as waste. Pruning residues from Giant Kelp Forests harvests for the Namibian coast provide large amounts of biomass. ALGOL project considers all these biomass residues as raw material for added value creation. The ALGOL feasibility project will develop and evaluate green technologies for phytosterol extraction from algae biomass in a biocascading approach. Fucosterol is chosen because of its high added value, whereas lipids, protein and carbohydrates are lower in value and will hence be evaluated in follow-up projects. ALGOL will develop subcritical water, supercritical CO2 with modifiers and ethanol extraction technologies and compare these with conventional petroleum-based extractions and asses its technical, economic and environmental feasibility. Prototype nutraceutical/cosmeceutical products will be developed to demonstrate possible applications with fucosterol. A network of Dutch and African partners will supply micro and macro algae biomass, evaluate developed technologies and will prototype products with it, which are relevant to their own business interests. ALGOL project will create added value by taking a biocascading approach where first high-interest components are processed into high added value products as nutraceutical or cosmeceutical.
To treat microbial infections, antibiotics are life-saving but the increasing antimicrobial resistance is a World-wide problem. Therefore, there is a great need for novel antimicrobial substances. Fruit and flower anthocyanins have been recognized as promising alternatives to traditional antibiotics. How-ever, for future application as innovative alternative antibiotics, the full potential of anthocyanins should be further investigated. The antimicrobial potential of anthocyanin mixtures against different bacterial species has been demonstrated in literature. Preliminary experiments performed by our laboratories, using grape, rose and red cabbage anthocyanins against S. aureus and E. coli confirmed the antimicrobial potential of these substances. Hundreds of different anthocyanin entities have been described. However, which of these entities hold antimicrobial effects is currently unknown. Our preliminary data show that an-thocyanins extracted from grape, rose and red cabbage contain different collections of anthocyanin entities with differential antimicrobial efficacies. Our focus is on the extraction and characterization of anthocyanins from various crop residues. Grape peels are residues in the production of wine, while red rose and tulip leaves are residues in the production of tulip bulbs and regular horticulture. The presence of high-grade substances for pharmacological purposes in these crops may provide an innovative strategy to add value to other-wise invaluable crop residues. This project will be performed by the collaborative effort of our institute together with the Medi-cal Microbiology department of the University Medical Center Groningen (UMCG), 'Wijnstaete', a small-scale wine-producer (Lemelerveld) and Imenz Bioengineering (Groningen), a company that develops processes to improve the production of biobased chemicals from waste products. Within this project, we will focus on the antimicrobial efficacy of anthocyanin-mixtures from sources that are abundantly and locally available as a residual waste product. The project is part of a larger re-search effect to further characterize, modify and study the antimicrobial effects of specific anthocy-anin entities.
