Every healthcare professional (HCP) in the Netherlands is expected to provide palliative care based on their initial education. This requires national consensus and clarity on the quality and goals of palliative care education and accessible education opportunities nationwide. These requirements were not met in the Netherlands, posing a major obstacle to improving the organization and delivery of palliative care. Therefore, a program, Optimizing Education and Training in Palliative Care (O2PZ), was established to improve palliative care education on a national level.
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Het doel van deze studie was het testen van een dertigtal familieleden op Charcot-Marie-Tooth type 1A met behulp van een real time kwantitatieve polymerase kettingreactie. Duplicatie van het gen werd bij 50 % van de familieleden gevonden, overeenkomend met Mendeliaanse overerving.
Standard SARS-CoV-2 testing protocols using nasopharyngeal/throat (NP/T) swabs are invasive and require trained medical staff for reliable sampling. In addition, it has been shown that PCR is more sensitive as compared to antigen-based tests. Here we describe the analytical and clinical evaluation of our in-house RNA extraction-free saliva-based molecular assay for the detection of SARS-CoV-2. Analytical sensitivity of the test was equal to the sensitivity obtained in other Dutch diagnostic laboratories that process NP/T swabs. In this study, 955 individuals participated and provided NP/T swabs for routine molecular analysis (with RNA extraction) and saliva for comparison. Our RT-qPCR resulted in a sensitivity of 82,86% and a specificity of 98,94% compared to the gold standard. A false-negative ratio of 1,9% was found. The SARS-CoV-2 detection workflow described here enables easy, economical, and reliable saliva processing, useful for repeated testing of individuals.
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The denim industry faces many complex sustainability challenges and has been especially criticized for its polluting and hazardous production practices. Reducing resource use of water, chemicals and energy and changing denim production practices calls for collaboration between various stakeholders, including competing denim brands. There is great benefit in combining denim brands’ resources and knowledge so that commonly defined standards and benchmarks are developed and realized on a scale that matters. Collaboration however, and especially between competitors, is highly complex and prone to fail. This project brings leading denim brands together to collectively take initial steps towards improving the ecological sustainability impact of denim production, particularly by establishing measurements, benchmarks and standards for resource use (e.g. chemicals, water, energy) and creating best practices for effective collaboration. The central research question of our project is: How do denim brands effectively collaborate together to create common, industry standards on resource use and benchmarks for improved ecological sustainability in denim production? To answer this question, we will use a mixed-method, action research approach. The project’s research setting is the Amsterdam Metropolitan Area (MRA), which has a strong denim cluster and is home to many international denim brands and start-ups.
De recente toename in het aantal bedwantsen in de Westerse wereld leidt ertoe dat steeds meer mensen in contact komen met deze insecten. Vroege detectie is cruciaal voor een snelle bestrijding. Dit is echter lastig door de cryptische leefwijze van de bedwants, en vereist vaak destructieve maatregelen. In dit project onderzoeken HAS Hogeschool en BioMon of het haalbaar is om een bedwantsdetectiekit te ontwikkelen waarmee de aanwezigheid van bedwants DNA in ruimten bepaald kan worden door het nemen van een swab of stofzuigersample. Bovendien wordt onderzocht hoe dit product en deze dienst efficiënt op de markt gezet kan worden.
Met dit project ‘Bouwstenen voor avontuurlijk spelen’ onderzoeken we hoe avontuurlijke speelplekken effectief (her)ingericht kunnen worden om daarmee het speel- en beweeggedrag van kinderen te bevorderen. Dit doen we door het gedrag van spelende kinderen op recent ingerichte avontuurlijke speelplekken in kaart te brengen en daarmee succes- en faalfactoren en ontwerpcriteria voor avontuurlijke speelplekken te bepalen. Zo ondersteunen we de gemeenten bij het vormgeven van toekomstige interventies.
